Potential Link between the Sphingosine-1-Phosphate (S1P) System and Defective Alveolar Macrophage Phagocytic Function in Chronic Obstructive Pulmonary Disease (COPD)

Oxidative Stress Decreases Functional Airway Mannose Binding Lectin in COPD

(2014) Hai B. Tran et al.   PLoS One

Vitamin D-responsive SGPP2 variants associated with lung cell expression and lung function

(2013) Brian J Reardon et al.   BMC Medical Genetics

Apoptotic cells enhance sphingosine-1-phosphate receptor 1 dependent macrophage migration

(2013) Benjamin Weichand et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Lectins Offer New Perspectives in the Development of Macrophage-Targeted Therapies for COPD/Emphysema

(2013) Violet R. Mukaro et al.   PLoS One

Defective Lung Macrophage Function in Lung Cancer±Chronic Obstructive Pulmonary Disease (COPD/Emphysema)-Mediated by Cancer Cell Production of PGE2?

(2013) Francis C. Dehle et al.   PLoS One

Osteoporosis in chronic obstructive pulmonary disease

(2013) Elisabeth APM Romme et al.   Expert Review of Respiratory Medicine

S1P Regulation of Macrophage Functions in the Context of Cancer

(2012) Andreas Weigert et al.   Anti-Cancer Agents in Medicinal Chemistry

Low-dose azithromycin improves phagocytosis of bacteria by both alveolar and monocyte-derived macrophagesin chronic obstructive pulmonary disease subjects

(2012) SANDRA HODGE et al.   RESPIROLOGY

Regulation of Mammalian Physiology, Development, and Disease by the Sphingosine 1-Phosphate and Lysophosphatidic Acid Receptors

(2011) Victoria A. Blaho et al.   CHEMICAL REVIEWS

Airway Clearance of Apoptotic Cells in COPD

(2011) Violet R.S. Mukaro et al.   CURRENT DRUG TARGETS

Expression profile of the sphingosine kinase signalling system in the lung of patients with chronic obstructive pulmonary disease

(2011) Fabian Cordts et al.   LIFE SCIENCES

Role of sphingosine-1-phosphate (S1P) and S1P receptor 2 in the phagocytosis of Cryptococcus neoformans by alveolar macrophages

(2011) T. McQuiston et al.   MICROBIOLOGY-SGM

Sphingosine Kinase 1 and Sphingosine 1-Phosphate Receptor 3 Are Functionally Upregulated on Astrocytes under Pro-Inflammatory Conditions

(2011) Iris Fischer et al.   PLoS One

Vitamin D-binding protein contributes to COPD by activation of alveolar macrophages

(2011) A. M. Wood et al.   THORAX

The role of sphingolipids in respiratory disease

(2011) Yang Yang et al.   Therapeutic Advances in Respiratory Disease

Fingolimod (FTY720) Enhances Remyelination Following Demyelination of Organotypic Cerebellar Slices

(2010) Veronique E. Miron et al.   AMERICAN JOURNAL OF PATHOLOGY

Neutral Sphingomyelinase 2

(2010) Simone Filosto et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Cigarette Smoke-Induced Changes to Alveolar Macrophage Phenotype and Function Are Improved by Treatment with Procysteine

(2010) Sandra Hodge et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Sphingosine-1-Phosphate Receptor-2 Function in Myeloid Cells Regulates Vascular Inflammation and Atherosclerosis

(2010) Athanasia Skoura et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vascular Barrier Regulation by PAF, Ceramide, Caveolae, and NO - an Intricate Signaling Network with Discrepant Effects in the Pulmonary and Systemic Vasculature

(2010) Wolfgang M. Kuebler et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Role of Host Sphingosine Kinase 1 in the Lung Response against Cryptococcosis

(2010) T. McQuiston et al.   INFECTION AND IMMUNITY

Sphingolipid-mediated Inhibition of Apoptotic Cell Clearance by Alveolar Macrophages

(2010) Daniela N. Petrusca et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice

(2010) Fei Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

The vitamin D axis in the lung: a key role for vitamin D-binding protein

(2010) L. Chishimba et al.   THORAX

Differential regulation of sphingosine kinases 1 and 2 in lung injury

(2009) Raj Wadgaonkar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Cigarette Smoke Impairs Clearance of Apoptotic Cells through Oxidant-dependent Activation of RhoA

(2009) Tiffany R. Richens et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Therapeutic Role for Mannose-Binding Lectin in Cigarette Smoke–Induced Lung Inflammation?

(2009) Sandra Hodge et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Acid Sphingomyelinase Inhibitors Normalize Pulmonary Ceramide and Inflammation in Cystic Fibrosis

(2009) Katrin Anne Becker et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Defective macrophage phagocytosis of bacteria in COPD

(2009) A. E. Taylor et al.   EUROPEAN RESPIRATORY JOURNAL

Regulation of macrophage function by sphingosine-1-phosphate

(2009) Andreas Weigert et al.   IMMUNOBIOLOGY

Regulation of Dendritic Cells and Macrophages by an Anti-Apoptotic Cell Natural Antibody that Suppresses TLR Responses and Inhibits Inflammatory Arthritis

(2009) Y. Chen et al.   JOURNAL OF IMMUNOLOGY

Sphingosine kinase 1 regulates the expression of proinflammatory cytokines and nitric oxide in activated microglia

(2009) D. Nayak et al.   NEUROSCIENCE

Azithromycin Improves Macrophage Phagocytic Function and Expression of Mannose Receptor in Chronic Obstructive Pulmonary Disease

(2008) Sandra Hodge et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Sphingolipids in the Lungs

(2008) Stefan Uhlig et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cytoskeleton and apoptosis

(2008) Olivia Ndozangue-Touriguine et al.   BIOCHEMICAL PHARMACOLOGY

Lung Cancer

(2008) Roy S. Herbst et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dual and distinct roles for sphingosine kinase 1 and sphingosine 1 phosphate in the response to inflammatory stimuli in RAW macrophages

(2007) Samar M. Hammad et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS