Article
Chemistry, Applied
Verena Huber, Laurie Muller, Pierre Degot, Didier Touraud, Werner Kunz
Summary: A choline chloride + lactic acid (1:1) NADES was used to enhance the solubility and extraction power of curcumin in ethanol/triacetin mixtures. The ternary system showed significant nanostructures and a twofold increase in curcumin solubility, enabling more extraction cycles with less solvent required to achieve the same yield.
Article
Nutrition & Dietetics
Humaira Ashraf, Masood Sadiq Butt, Iahtisham-Ul-Haq, Muhammad Nadeem, Rana Muhammad Aadil, Alexandru Vasile Rusu, Monica Trif
Summary: This study demonstrates that the modulation of hypercholesterolemia can be achieved through the use of microencapsulated curcumin, resulting in reduced cholesterol and triglyceride levels and increased high-density lipoproteins.
FRONTIERS IN NUTRITION
(2022)
Article
Chemistry, Physical
Pierre Degot, Verena Huber, Asmae El Maangar, Johannes Gramueller, Lea Rohr, Didier Touraud, Thomas Zemb, Ruth M. Gschwind, Werner Kunz
Summary: The study investigated a ternary solvent system composed of water/sodium salicylate/ethyl acetate for the extraction, solubilization, and stabilization of curcumin from Curcuma longa. Good extraction yields were achieved in the area of best solubility, while the protective effect of sodium salicylate on curcumin oxidation was found to be significant.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Review
Agronomy
Adrian Bondar, Loredana Horodincu, Gheorghe Solcan, Carmen Solcan
Summary: The review article highlights the nutraceutical properties of turmeric and spirulina in the broiler chicken industry. Spirulina is rich in protein, carbohydrates, essential amino acids, and fatty acids, and it exhibits positive effects on growth performance, gut integrity, and immunity. Turmeric also positively influences growth, egg production, and overall health of chickens, with curcumin possessing additional pharmacological activities including immunostimulation and hepatoprotection.
Article
Agronomy
Kylie Tavares, Emilie Kirk, Sharon Motomura-Wages, Justin Calpito, Jon-Paul Bingham, Amjad A. Ahmad, Kevin Flanagan, Jensen Uyeda, Michael B. Kantar, Theodore J. K. Radovich
Summary: Turmeric and its constituent curcuminoid compounds have been traditionally used for their medicinal properties. Recent studies have confirmed their anti-inflammatory, antioxidant, and anticarcinogenic properties. Our research in Hawaii suggests that turmeric yield is influenced by genotype and environmental factors, with suboptimal temperatures at high elevations impacting yield. However, high yielding turmeric varieties show adaptability across diverse environments, but further evaluations are needed in non-optimal environments and high pest pressure areas.
Article
Chemistry, Physical
Pierre Degot, Diana Funkner, Verena Huber, Moritz Koeglmaier, Didier Touraud, Werner Kunz
Summary: The study demonstrates that the addition of meglumine and pyroglutamic acid can significantly enhance the extraction of curcuminoids from Curcuma longa. By adding meglumine to the extraction mixture, a higher yield of curcuminoids could be achieved.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Applied
Pierre Degot, Verena Huber, Evamaria Hofmann, Maximilian Hahn, Didier Touraud, Werner Kunz
Summary: The study compares the extraction performance of two green and bio-based surfactant-free microemulsion systems and finds that SFME containing ethanol extracts curcuminoids the most effectively.
Review
Integrative & Complementary Medicine
Zeinab Vafaeipour, Bibi Marjan Razavi, Hossein Hosseinzadeh
Summary: This paper provides an updated review on the effects of turmeric and its constituent, curcumin, on metabolic syndrome (MS). Studies have shown that turmeric and curcumin have beneficial effects on different components of MS, including anti-inflammatory, anti-oxidant, antidiabetic, antihyperlipidemic, anti-obesity, and antihypertensive effects. The findings suggest that turmeric or curcumin may serve as a complementary therapy for MS. However, more clinical trials are needed to confirm these effects.
JOURNAL OF INTEGRATIVE MEDICINE-JIM
(2022)
Article
Computer Science, Artificial Intelligence
Agus Pratondo, Elfahmi Elfahmi, Astri Novianty
Summary: The study aims to build a model that can distinguish between turmeric and temulawak based on images captured from a mobile phone camera. By using transfer learning, the models achieved high accuracy rates.
PEERJ COMPUTER SCIENCE
(2022)
Article
Chemistry, Analytical
Nhan Trong Le, Nguyen Thuy Hoang, Van Tuong Thi Van, Trieu Phat Dac Nguyen, Ngoc Huyen Thi Chau, Nguyen Thao Nguyen Le, Hien Bich Thi Le, Huong Thanh Phung, Hoai Thi Nguyen, Hien Minh Nguyen
Summary: This study used deep eutectic solvents (DESs) and surfactant solvents (SSs) to extract curcumin from turmeric residues (TRs). Choline chloride-propylene glycol (ChCl-Pro) showed the highest yield among the solvents used. The optimized extraction conditions achieved a curcumin yield of 54.2 mg g(-1), which was 1.31 times higher than using methanol as a solvent. The recovered curcumin exhibited antioxidant and acetylcholinesterase (AChE) inhibitory activities.
ANALYTICAL METHODS
(2022)
Review
Pharmacology & Pharmacy
Shivkanya Fuloria, Jyoti Mehta, Aditi Chandel, Mahendran Sekar, Nur Najihah Izzati Mat Rani, M. Yasmin Begum, Vetriselvan Subramaniyan, Kumarappan Chidambaram, Lakshmi Thangavelu, Rusli Nordin, Yuan Seng Wu, Kathiresan Sathasivam, Pei Teng Lum, Dhanalekshmi Unnikrishnan Meenakshi, Vinoth Kumarasamy, Abul Kalam Azad, Neeraj Kumar Fuloria
Summary: Curcuma longa, commonly known as turmeric, has a long history of medicinal use. Its major constituent, curcumin, is well known for its therapeutic potential in various disorders. However, there is still a lack of literature and clinical trials on the therapeutic potential of turmeric. Further research is needed to explore its phytochemical ingredients, pharmacology, toxicity, and safety aspects, as well as its relationship with curcumin.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Chemistry, Analytical
Wuyi Nie, Qiao Lu, Tao Hu, Min Xie, Yongjun Hu
Summary: This article visualized the distribution of curcumin in turmeric using vacuum-ultraviolet single photon postionization mass spectrometric imaging. The concentration of curcumin was found to decrease from the phloem to the xylem of the root. The study also analyzed the transformation of curcumin in turmeric roots at different maturity periods.
Article
Agricultural Engineering
R. Dinesh, V. Srinivasan, R. Praveena, K. P. Subila, Priya George, Akshaya Das, O. Shajina, K. Anees, N. K. Leela, P. Haritha
Summary: This study investigated the effects of phosphorus solubilizing bacteria (PSB) on turmeric yield and quality. The results showed that certain bacterial strains were able to produce organic acids, enhancing P solubilization. Greenhouse and field experiments demonstrated that combined application of PSB and phosphate significantly increased soil available P, rhizome yield, P uptake, and curcumin content compared to control treatments.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Chemistry, Applied
Pierre Degot, Verena Huber, Didier Touraud, Werner Kunz
Summary: Curcumin was extracted from Curcuma Longa using a surfactant-free microemulsion, producing highly concentrated tinctures of up to 130 mg/mL curcuminoids. Water content influenced the extraction process and the purity of the extracts, with additional purification steps enhancing purity to 94%. Purification before extraction allowed for indefinite solubilization of water insoluble curcumin extracts in aqueous environments, with stability of the solutions for up to five months when kept away from natural light.
Article
Multidisciplinary Sciences
Dewi Setyaningsih, Yosua Agung Santoso, Yustina Sri Hartini, Yosi Bayu Murti, Wouter L. J. Hinrichs, Christine Patramurti
Summary: The study developed a simple HPLC method to quantify curcumin and piperine content in a solid dispersion based microparticle formulation, achieving satisfactory separation of the compounds and validating the method according to ICH guidelines.
Article
Chemistry, Applied
Manaswini Dash, Subhashree Singh, Bhaskar Chandra Sahoo, Suprava Sahoo, Rajesh Kumar Sahoo, Sanghamitra Nayak, Basudeba Kar
Summary: The study analyzed the volatile components in Piper longum leaf and fruit, showing that the fruit volatiles had higher antioxidant and free radical scavenging activities, exhibiting strong activity against multidrug resistant bacteria, particularly Acinetobacter baumannii. Therefore, dried fruits may be used for drug development.
NATURAL PRODUCT RESEARCH
(2022)
Article
Plant Sciences
Pradeep Kumar Kamila, Asit Ray, Sudipta Jena, Ambika Sahoo, Subrat Kumar Kar, Sanghamitra Nayak, Pratap Chandra Panda
Summary: The study investigated the variation in yield and chemical composition of essential oil isolated from seven wild populations of Hypericum gaitii from Eastern India. The essential oils were found to contain a diverse range of chemical constituents, with distinct chemotypes identified based on principal component analysis and hierarchical clustering. The results suggest that geographical origin and environmental factors significantly influence the essential oil properties of H. gaitii.
Article
Biochemistry & Molecular Biology
Bibhuti Bhusan Champati, Bhuban Mohan Padhiari, Asit Ray, Tarun Halder, Sudipta Jena, Ambika Sahoo, Basudeba Kar, Pradeep Kumar Kamila, Pratap Chandra Panda, Biswajit Ghosh, Sanghamitra Nayak
Summary: This study used a multilayer perceptron artificial neural network to investigate the abiotic factors affecting the andrographolide content of Andrographis paniculata and select suitable cultivation sites with high andrographolide content. The results showed that nitrogen, phosphorus, and potassium were the predominant factors influencing the andrographolide content.
Article
Plant Sciences
Bhuban Mohan Padhiari, Asit Ray, Bibhuti Bhusan Champati, Sudipta Jena, Ambika Sahoo, Ananya Kuanar, Tarun Halder, Biswajit Ghosh, Pradeep Kumar Naik, Jeetendranath Patnaik, Sujata Mohanty, Pratap Chandra Panda, Sanghamitra Nayak
Summary: The aim of this research is to study the drug environment interactions and predict the bacoside A content in Bacopa monnieri using an artificial neural network model. The results showed that the multilayer perceptron neural network with a single hidden layer and 11 neurons had the highest prediction accuracy. Sensitivity analysis indicated that nitrogen levels and altitude had the greatest impact on bacoside A content. The ANN model demonstrated a prediction accuracy of 93.60% when tested at a new geographical location.
Article
Biotechnology & Applied Microbiology
Bhagyashree Biswal, Biswajit Jena, Alok Kumar Giri, Laxmikanta Acharya
Summary: The study found that blue light in LEDs can increase biomass accumulation, pigment concentration, and production of bioactive metabolites in Operculina turpethum callus culture. Blue light also enhances in vitro antioxidant activity in callus culture. However, callus culture grown under dark conditions showed higher expression of superoxide dismutase and catalase enzymes. Quantification of phytochemicals revealed highest production under blue light treatment.
PLANT CELL TISSUE AND ORGAN CULTURE
(2022)
Article
Multidisciplinary Sciences
Alok Kumar Giri, Biswajit Jena, Bhagyashree Biswal, Arun Kumar Pradhan, Manoranjan Arakha, Saumyaprava Acharya, Laxmikanta Acharya
Summary: The study successfully synthesized silver nanoparticles using a green synthesis approach and demonstrated their effectiveness in inhibiting biofilm formation. This could be a significant breakthrough in combating various dynamic pathogens.
SCIENTIFIC REPORTS
(2022)
Article
Food Science & Technology
Alok Kumar Giri, Bhagyashree Biswal, Biswajit Jena, Laxmikanta Acharya
Summary: Eugenia roxburghii, a wild edible plant, possesses pharmacological and nutritional properties. It contains abundant polyphenols and flavonoids, showing significant scavenging activity against reactive oxygen species. Nutritionally, E. roxburghii is rich in vitamin C and provides a substantial amount of calories, carbohydrates, protein, and dietary fiber.
Article
Agricultural Engineering
Suryasnata Das, I. Sriram Sandeep, Priyanka Mohapatra, Basudeba Kar, Rajesh Kumar Sahoo, Enketeswara Subudhi, Sanghamitra Nayak, Sujata Mohanty
Summary: Betelvine is an economically and medicinally important crop in many Asian countries. Its leaves are used for medicinal purposes and the essential oil derived from the leaves has antiseptic and antioxidant properties. This study analyzed the chemical composition and bioactivity of thirty different landraces of betelvine, identifying high-yielding and high-chavibetol content varieties with potential for commercial use.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Biochemistry & Molecular Biology
Biswajit Jena, Bhagyashree Biswal, Ashirbad Sarangi, Alok Kumar Giri, Debapriya Bhattacharya, Laxmikanta Acharya
Summary: Plectranthus amboinicus, also known as Indian borage or Mexican mint, is a highly documented species in the Lamiaceae family known for its medicinal properties. The leaf essential oil extracted from this plant has various therapeutic benefits and shows efficient bactericidal effects against both gram positive and gram negative bacteria. The study conducted in Odisha, India, found that the germplasm from this region is preferable for obtaining high-quality leaf oil with potential pharmaceutical use.
CHEMISTRY & BIODIVERSITY
(2023)
Article
Plant Sciences
Bijayalaxmi Mahanty, Rukmini Mishra, Raj Kumar Joshi
Summary: Fusarium basal rot (FBR), caused by Fusarium oxysporum f. sp. cepae (Foc), is a severe fungal disease affecting onion and allied crops worldwide. Small RNAs (sRNAs) derived from Foc were found to facilitate cross-kingdom RNA interference (RNAi), suppress host immune response, and increase susceptibility of onion to FBR infection.
PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Bijayalaxmi Mahanty, Rukmini Mishra, Raj Kumar Joshi
Summary: Small RNAs (sRNAs) play important roles in plant disease resistance and fungal pathogenicity by moving between plants and fungi. They can silence host mRNAs and inhibit immunity genes, as well as silence pathogenicity-related genes in fungi. This review focuses on the mechanism of cross-kingdom communication through sRNA trafficking and its potential implications for pathogen and pest control in agriculture.
Article
Biotechnology & Applied Microbiology
Jayashree Sahoo, Bijayalaxmi Mahanty, Rukmini Mishra, Raj Kumar Joshi
Summary: Purple blotch (PB), caused by Alternaria porri, is a destructive disease of onion. Developing resistant onion varieties is the most effective approach to control PB. This study used SNP markers to fine map the resistance locus in an RIL population derived from a resistant and susceptible cultivar. Six KASP markers, including ApRsnip14 and ApRsnip23, were found tightly associated with the PB resistance gene ApR1.
Article
Plant Sciences
Bijayalaxmi Mahanty, Rukmini Mishra, Raj Kumar Joshi
Summary: This study compared the miRNA profiles of resistant and susceptible onion cultivars, and identified 37 differentially expressed miRNAs that play a crucial role in defense against Fusarium oxysporum f. sp. cepae (Foc). The study also discovered a novel onion miRNA, ace-miRn3a, which enhances onion resistance to Foc by suppressing TIR1 F-box proteins.
PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY
(2023)
Article
Chemistry, Medicinal
Sudipta Jena, Asit Ray, Ambika Sahoo, Prabhat Kumar Das, Bibhuti Bhusan Champati, Sanghamitra Nayak, Pratap Chandra Panda
CHEMISTRY OF NATURAL COMPOUNDS
(2022)
Article
Plant Sciences
Wanli You, Jinglin Zhang, Xueyin Ru, Feng Xu, Zhengguo Wu, Peng Jin, Yonghua Zheng, Shifeng Cao
Summary: This study investigated the effect of calcium chloride (CaCl2) treatment on GABA accumulation in fresh-cut cantaloupe and the underlying mechanisms. The results showed that CaCl2 treatment increased GABA content and the activities of GAD and SSADH enzymes, while reducing glutamate content and GABA-T activity. Additionally, CaCl2 treatment upregulated the expressions of CmCML11 and CmCAMTA5, as well as several GABA shunt genes, through the transcriptional activation by CmCAMTA5. Furthermore, the interaction between CmCML11 and CmCAMTA5 enhanced the transcriptional activation of GABA shunt genes. Overall, this study reveals that CaCl2 treatment promotes GABA accumulation in fresh-cut cantaloupe through the combined effect of CmCML11 and CmCAMTA5 in regulating the expressions of GABA shunt genes.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
Min Wang, Yupeng Wang, Xiaohui Wang, Guangwei Wei, Huiyi Yang, Xi Yang, Tinghai Shen, Huijie Qu, Sheng Fang, Ziming Wu
Summary: This study identified the high nitrogen use efficiency (NUE) black sesame variety 17-156 and analyzed its underlying physiological and molecular mechanisms. The results showed that 17-156 possesses a sophisticated nitrogen metabolizing machinery to uptake and assimilate higher quantities of inorganic nitrogen, simultaneously improving carbon metabolism and growth. Many important genes were up-regulated in 17-156 under high nitrogen condition. Additionally, 38 potential candidate genes were identified for future studies to improve sesame's NUE. These findings provide valuable resources for understanding the regulatory network of nitrogen metabolism and developing sesame cultivars with improved NUE.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
He Dong, Chongmei Xu, Chengtao Zhang, Li Zhang, Yaqin Yao, Suiqi Zhang
Summary: The study found that short cells in maize leaves not only improve leaf mechanical support and photosynthetic performance, enhance drought resistance, but also participate in stomatal regulation.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
Na Liu, Wenyan Shang, Mengxin Guan, Jibin Xiao, Guangxiang Tian, Baozhan Ma, Wenjing Shang, Xu Li, Shijia Zhao, Chuang Li, Kun Cheng, Wenming Zheng
Summary: This study cloned the full-length cDNA sequence of TaSPX3 gene in wheat and found that TaSPX3 responds to low phosphorus stress in multiple wheat genotypes. Overexpressing TaSPX3 can alleviate phosphorus deficiency symptoms and promote plant growth in Arabidopsis. The study also revealed the interaction of TaSPX3 with other genes related to the phosphorus starvation signaling pathway.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
Kongyuan Wu, Lizhen Wang, Zihan Wu, Ziqing Liu, Zengfei Li, Jun Shen, Shengjie Shi, Hong Liu, Christopher Rensing, Renwei Feng
Summary: Selenium (Se) can reduce uptake and translocation of cadmium (Cd) in plants by regulating root morphology. This study investigated the effects of Se(IV) on root exudates, root morphology, root endogenous hormones, and Cd uptake efficiency in rice under Cd stress. The results showed that Se(IV) significantly reduced Cd concentrations in shoots and roots, and decreased Cd uptake efficiency via root hairs. Se(IV) also affected root morphology, root exudates, and the synthesis of hormones like IAA and JA. However, transcriptome analysis revealed no upregulated differentially expressed genes (DEGs) in IAA synthesis.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
Di Wang, Huaifang Zhang, Xuefei Hu, Haizhen Zhang, Shuang Feng, Aimin Zhou
Summary: This study identified a cell number regulator gene called SlCNR8 in willow, which enhances resistance to trace metals in transgenic poplar seedlings. SlCNR8 reduces Cd uptake and accumulation, and can be used as a candidate gene for genetic improvement of phytostabilisation of trace metals.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)