An apoptosis-driven ‘onco-regenerative niche’: roles of tumour-associated macrophages and extracellular vesicles

Disassembly of the Dying: Mechanisms and Functions

(2017) Georgia K. Atkin-Smith et al.   TRENDS IN CELL BIOLOGY

Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis

(2016) Annette Becker et al.   CANCER CELL

Extracellular vesicle transfer of cancer pathogenic components

(2016) Yu Fujita et al.   CANCER SCIENCE

Exposure of phosphatidylserine on the cell surface

(2016) S Nagata et al.   CELL DEATH AND DIFFERENTIATION

Erythropoeitin Signaling in Macrophages Promotes Dying Cell Clearance and Immune Tolerance

(2016) Bangwei Luo et al.   IMMUNITY

Correction of MFG-E8 Resolves Inflammation and Promotes Cutaneous Wound Healing in Diabetes

(2016) Amitava Das et al.   JOURNAL OF IMMUNOLOGY

Low levels of Caspase-3 predict favourable response to 5FU-based chemotherapy in advanced colorectal cancer: Caspase-3 inhibition as a therapeutic approach

(2016) L Flanagan et al.   Cell Death & Disease

Oncogenic Properties of Apoptotic Tumor Cells in Aggressive B Cell Lymphoma

(2015) Catriona A. Ford et al.   CURRENT BIOLOGY

Spreading the word: non-autonomous effects of apoptosis during development, regeneration and disease

(2015) Ainhoa Pérez-Garijo et al.   DEVELOPMENT

Increased HMGB1 and cleaved caspase-3 stimulate the proliferation of tumor cells and are correlated with the poor prognosis in colorectal cancer

(2015) Zhengxiang Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Loss of Cell Surface CD47 Clustering Formation and Binding Avidity to SIRPα Facilitate Apoptotic Cell Clearance by Macrophages

(2015) Zhiyuan Lv et al.   JOURNAL OF IMMUNOLOGY

Phagocytosis of apoptotic cells in homeostasis

(2015) Sanja Arandjelovic et al.   NATURE IMMUNOLOGY

The 20 S proteasome core, active within apoptotic exosome-like vesicles, induces autoantibody production and accelerates rejection

(2015) Mélanie Dieudé et al.   Science Translational Medicine

Mer receptor tyrosine kinase mediates both tethering and phagocytosis of apoptotic cells

(2015) I Dransfield et al.   Cell Death & Disease

A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure

(2015) Georgia K. Atkin-Smith et al.   Nature Communications

Expression of caspase-3 predicts prognosis in advanced noncardia gastric cancer

(2014) Sousana Amptoulach et al.   MEDICAL ONCOLOGY

Dying tumor cells stimulate proliferation of living tumor cells via caspase-dependent protein kinase Cδ activation in pancreatic ductal adenocarcinoma

(2014) Jin Cheng et al.   Molecular Oncology

Diversification of TAM receptor tyrosine kinase function

(2014) Anna Zagórska et al.   NATURE IMMUNOLOGY

Dying Cells Protect Survivors from Radiation-Induced Cell Death in Drosophila

(2014) Amber Bilak et al.   PLoS Genetics

Blebs produced by actin–myosin contraction during apoptosis release damage-associated molecular pattern proteins before secondary necrosis occurs

(2013) G R Wickman et al.   CELL DEATH AND DIFFERENTIATION

Enhanced Efferocytosis of Apoptotic Cardiomyocytes Through Myeloid-Epithelial-Reproductive Tyrosine Kinase Links Acute Inflammation Resolution to Cardiac Repair After Infarction

(2013) Elaine Wan et al.   CIRCULATION RESEARCH

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Xk-Related Protein 8 and CED-8 Promote Phosphatidylserine Exposure in Apoptotic Cells

(2013) J. Suzuki et al.   SCIENCE

Clearing the Dead: Apoptotic Cell Sensing, Recognition, Engulfment, and Digestion

(2013) A. Hochreiter-Hufford et al.   Cold Spring Harbor Perspectives in Biology

Sustained production of ROS triggers compensatory proliferation and is required for regeneration to proceed

(2013) Carole Gauron et al.   Scientific Reports

Apoptotic cells can induce non-autonomous apoptosis through the TNF pathway

(2013) Ainhoa Pérez-Garijo et al.   eLife

Sweet kiss of dying cell: Sialidase activity on apoptotic cell is able to act toward its neighbors

(2012) Tanya Shkandina et al.   AUTOIMMUNITY

Apoptotic cell clearance by bronchial epithelial cells critically influences airway inflammation

(2012) Ignacio J. Juncadella et al.   NATURE

Injury-induced activation of the MAPK/CREB pathway triggers apoptosis-induced compensatory proliferation in hydra head regeneration

(2011) Simona Chera et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

The seed and soil hypothesis revisited-The role of tumor-stroma interactions in metastasis to different organs

(2011) Robert R. Langley et al.   INTERNATIONAL JOURNAL OF CANCER

Caspase 3–mediated stimulation of tumor cell repopulation during cancer radiotherapy

(2011) Qian Huang et al.   NATURE MEDICINE

TAM receptors and the clearance of apoptotic cells

(2010) Greg Lemke et al.   Annals of the New York Academy of Sciences

Microenvironmental influences of apoptosis in vivo and in vitro

(2010) Christopher D. Gregory et al.   APOPTOSIS

Signals from dying hepatocytes trigger growth of liver progenitors

(2010) Y. Jung et al.   GUT

Impaired Apoptotic Cell Clearance in the Germinal Center by Mer-Deficient Tingible Body Macrophages Leads to Enhanced Antibody-Forming Cell and Germinal Center Responses

(2010) Z. S. M. Rahman et al.   JOURNAL OF IMMUNOLOGY

Cell death in the neighbourhood: direct microenvironmental effects of apoptosis in normal and neoplastic tissues

(2010) Christopher D Gregory et al.   JOURNAL OF PATHOLOGY

PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury

(2010) T. E. North et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apoptotic Cells Activate the "Phoenix Rising" Pathway to Promote Wound Healing and Tissue Regeneration

(2010) F. Li et al.   Science Signaling

CD47 Is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis

(2009) Siddhartha Jaiswal et al.   CELL

Horizontal transfer of tumor DNA to endothelial cells in vivo

(2009) J Ehnfors et al.   CELL DEATH AND DIFFERENTIATION

The role of Dpp and Wg in compensatory proliferation and in the formation of hyperplastic overgrowths caused by apoptotic cells in the Drosophila wing disc

(2009) A. Perez-Garijo et al.   DEVELOPMENT

Apoptotic Cells Provide an Unexpected Source of Wnt3 Signaling to Drive Hydra Head Regeneration

(2009) Simona Chera et al.   DEVELOPMENTAL CELL

Inhibition of eosinophil migration by lactoferrin

(2009) Irini Bournazou et al.   IMMUNOLOGY AND CELL BIOLOGY

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

(2009) Michael R. Elliott et al.   NATURE

CX3CL1/fractalkine is released from apoptotic lymphocytes to stimulate macrophage chemotaxis

(2008) L. A. Truman et al.   BLOOD

Distinct Mechanisms of Apoptosis-Induced Compensatory Proliferation in Proliferating and Differentiating Tissues in the Drosophila Eye

(2008) Yun Fan et al.   DEVELOPMENTAL CELL

Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a “come-and-get-me” signal

(2008) David R. Gude et al.   FASEB JOURNAL

Apoptotic human cells inhibit migration of granulocytes via release of lactoferrin

(2008) Irini Bournazou et al.   JOURNAL OF CLINICAL INVESTIGATION