XIST RNA: a window into the broader role of RNA in nuclear chromosome architecture

Prion-like domains as epigenetic regulators, scaffolds for subcellular organization, and drivers of neurodegenerative disease

(2016) Zachary M. March et al.   BRAIN RESEARCH

RNA as a fundamental component of interphase chromosomes: could repeats prove key?

(2016) Lisa L Hall et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Control of Chromosomal Localization of Xist by hnRNP U Family Molecules

(2016) Takehisa Sakaguchi et al.   DEVELOPMENTAL CELL

SAF-A Requirement in Anchoring XIST RNA to Chromatin Varies in Transformed and Primary Cells

(2016) Heather J. Kolpa et al.   DEVELOPMENTAL CELL

Comprehensive Identification of RNA-Binding Domains in Human Cells

(2016) Alfredo Castello et al.   MOLECULAR CELL

Structural organization of the inactive X chromosome in the mouse

(2016) Luca Giorgetti et al.   NATURE

Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing

(2016) C.-K. Chen et al.   SCIENCE

Fitting the Puzzle Pieces: the Bigger Picture of XCI

(2016) Cheryl Maduro et al.   TRENDS IN BIOCHEMICAL SCIENCES

Systematic Discovery of Xist RNA Binding Proteins

(2015) Ci Chu et al.   CELL

Erosion of X Chromosome Inactivation in Human Pluripotent Cells Initiates with XACT Coating and Depends on a Specific Heterochromatin Landscape

(2015) Céline Vallot et al.   Cell Stem Cell

Transposable elements and G-quadruplexes

(2015) Eduard Kejnovsky et al.   CHROMOSOME RESEARCH

The inactive X chromosome is epigenetically unstable and transcriptionally labile in breast cancer

(2015) Ronan Chaligné et al.   GENOME RESEARCH

The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3

(2015) Colleen A. McHugh et al.   NATURE

A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation

(2015) A. Minajigi et al.   SCIENCE

Nuclear Fractionation Reveals Thousands of Chromatin-Tethered Noncoding RNAs Adjacent to Active Genes

(2015) Michael S. Werner et al.   Cell Reports

A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing

(2015) Benoit Moindrot et al.   Cell Reports

New Perspectives on DNA and RNA Triplexes As Effectors of Biological Activity

(2015) Albino Bacolla et al.   PLoS Genetics

Unfolding the story of chromatin organization in senescent cells

(2015) Eric C Swanson et al.   Nucleus

Unfolding the story of chromatin organization in senescent cells

(2015) Eric C Swanson et al.   Nucleus

Stable C0T-1 Repeat RNA Is Abundant and Is Associated with Euchromatic Interphase Chromosomes

(2014) Lisa L. Hall et al.   CELL

ATRX Directs Binding of PRC2 to Xist RNA and Polycomb Targets

(2014) Kavitha Sarma et al.   CELL

Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre

(2014) Ezgi Hacisuleyman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Three-dimensional super-resolution microscopy of the inactive X chromosome territory reveals a collapse of its active nuclear compartment harboring distinct Xist RNA foci

(2014) Daniel Smeets et al.   Epigenetics & Chromatin

Higher-order unfolding of satellite heterochromatin is a consistent and early event in cell senescence

(2013) Eric C. Swanson et al.   JOURNAL OF CELL BIOLOGY

High-resolution Xist binding maps reveal two-step spreading during X-chromosome inactivation

(2013) Matthew D. Simon et al.   NATURE

Translating dosage compensation to trisomy 21

(2013) Jun Jiang et al.   NATURE

The Xist lncRNA Exploits Three-Dimensional Genome Architecture to Spread Across the X Chromosome

(2013) J. M. Engreitz et al.   SCIENCE

Deletion of an X-Inactivation Boundary Disrupts Adjacent Gene Silencing

(2013) Lindsay M. Horvath et al.   PLoS Genetics

Independence of Repressive Histone Marks and Chromatin Compaction during Senescent Heterochromatic Layer Formation

(2012) Tamir Chandra et al.   MOLECULAR CELL

The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA

(2011) E. Splinter et al.   GENES & DEVELOPMENT

A scaffold for X chromosome inactivation

(2011) Anna Tattermusch et al.   HUMAN GENETICS

Revisiting the function of nuclear scaffold/matrix binding proteins in X chromosome inactivation

(2011) Yuko Hasegawa et al.   RNA Biology

eXIST with matrix-associated proteins

(2011) Shinichi Nakagawa et al.   TRENDS IN CELL BIOLOGY

Coding RNAs with a non-coding function: Maintenance of open chromatin structure

(2011) Maïwen Caudron-Herger et al.   Nucleus

The Trithorax group protein Ash2l and Saf-A are recruited to the inactive X chromosome at the onset of stable X inactivation

(2010) D. Pullirsch et al.   DEVELOPMENT

The Matrix Protein hnRNP U Is Required for Chromosomal Localization of Xist RNA

(2010) Yuko Hasegawa et al.   DEVELOPMENTAL CELL

Global survey of escape from X inactivation by RNA-sequencing in mouse

(2010) F. Yang et al.   GENOME RESEARCH

Transposable elements have rewired the core regulatory network of human embryonic stem cells

(2010) Galih Kunarso et al.   NATURE GENETICS

Changing nuclear landscape and unique PML structures during early epigenetic transitions of human embryonic stem cells

(2009) John T. Butler et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Evolution of the mammalian transcription factor binding repertoire via transposable elements

(2008) G. Bourque et al.   GENOME RESEARCH