Hypoxia Downregulates MAPK/ERK but Not STAT3 Signaling in ROS-Dependent and HIF-1-Independent Manners in Mouse Embryonic Stem Cells

The stabilization of hypoxia inducible factor modulates differentiation status and inhibits the proliferation of mouse embryonic stem cells

(2016) Lucia Binó et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Redox Homeostasis and Cellular Antioxidant Systems: Crucial Players in Cancer Growth and Therapy

(2016) Barbara Marengo et al.   Oxidative Medicine and Cellular Longevity

Apocynin and Diphenyleneiodonium Induce Oxidative Stress and Modulate PI3K/Akt and MAPK/Erk Activity in Mouse Embryonic Stem Cells

(2016) Jan Kučera et al.   Oxidative Medicine and Cellular Longevity

Role of ROS and RNS Sources in Physiological and Pathological Conditions

(2016) Sergio Di Meo et al.   Oxidative Medicine and Cellular Longevity

ROS and ROS-Mediated Cellular Signaling

(2016) Jixiang Zhang et al.   Oxidative Medicine and Cellular Longevity

Prognostic role of STAT3 in solid tumors: a systematic review and meta-analysis

(2016) Pin Wu et al.   Oncotarget

Alkaline Phosphatase in Stem Cells

(2015) Kateřina Štefková et al.   Stem Cells International

Multiple regulation pathways and pivotal biological functions of STAT3 in cancer

(2015) Jie Yuan et al.   Scientific Reports

Deferoxamine Promotes MDA-MB-231 Cell Migration and Invasion through Increased ROS-Dependent HIF-1a Accumulation

(2014) Yiping Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Hypoxia induces re-entry of committed cells into pluripotency

(2013) Julie Mathieu et al.   STEM CELLS

ERK1/2 MAP kinases: Structure, function, and regulation

(2012) Robert Roskoski   PHARMACOLOGICAL RESEARCH

Growth/differentiation factor-15: prostate cancer suppressor or promoter?

(2012) P Vaňhara et al.   PROSTATE CANCER AND PROSTATIC DISEASES

Phosphoinositide 3-kinase inhibition enables retinoic acid-induced neurogenesis in monolayer culture of embryonic stem cells

(2011) Hana Kotasová et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Pharmacological Characterization of 1-(5-Chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic Acid (JNJ-42041935), a Potent and Selective Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor

(2011) T. D. Barrett et al.   MOLECULAR PHARMACOLOGY

The dual-specificity MAP kinase phosphatases: critical roles in development and cancer

(2010) O. Bermudez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Effect of long-term culture of mouse embryonic stem cells under low oxygen concentration as well as on glycosaminoglycan hyaluronan on cell proliferation and differentiation

(2010) M. Á. Ramírez et al.   CELL PROLIFERATION

Post-transcriptional regulation of the DUSP6/MKP-3 phosphatase by MEK/ERK signaling and hypoxia

(2010) Olga Bermudez et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Hypoxia Promotes Efficient Differentiation of Human Embryonic Stem Cells to Functional Endothelium

(2010) Sonia Prado-Lopez et al.   STEM CELLS

Regulation of the inducible nuclear dual-specificity phosphatase DUSP5 by ERK MAPK

(2009) Anna Kucharska et al.   CELLULAR SIGNALLING

Hypoxia-activated Smad3-specific Dephosphorylation by PP2A

(2009) Pekka T. Heikkinen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia-inducible factors in stem cells and cancer

(2009) Jolly Mazumdar et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Redox Regulation of Cell Survival

(2008) Dunyaporn Trachootham et al.   ANTIOXIDANTS & REDOX SIGNALING

Effects of oxygen on mouse embryonic stem cell growth, phenotype retention, and cellular energetics

(2008) Daryl E. Powers et al.   BIOTECHNOLOGY AND BIOENGINEERING

A reduced oxygen tension (5%) is not beneficial for maintaining human embryonic stem cells in the undifferentiated state with short splitting intervals

(2008) H.-F. Chen et al.   HUMAN REPRODUCTION

Detection of 2-hydroxyethidium in cellular systems: a unique marker product of superoxide and hydroethidine

(2007) Jacek Zielonka et al.   Nature Protocols