Sepsis-Induced Cardiomyopathy: Oxidative Implications in the Initiation and Resolution of the Damage

Endotoxemia Engages the RhoA Kinase Pathway to Impair Cardiac Function By Altering Cytoskeleton, Mitochondrial Fission, and Autophagy

(2016) Sebastien Preau et al.   ANTIOXIDANTS & REDOX SIGNALING

Naringin protects against lipopolysaccharide-induced cardiac injury in mice

(2016) Liu Xianchu et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

The synthetic antimicrobial peptide 19-2.5 attenuates mitochondrial dysfunction in cardiomyocytes stimulated with human sepsis serum

(2016) Lukas Martin et al.   Innate Immunity

Oxidative-Nitrosative Stress and Myocardial Dysfunctions in Sepsis: Evidence from the Literature and Postmortem Observations

(2016) M. Neri et al.   MEDIATORS OF INFLAMMATION

Mitochondria-Targeted Antioxidants: Future Perspectives in Kidney Ischemia Reperfusion Injury

(2016) Aleksandra Kezic et al.   Oxidative Medicine and Cellular Longevity

Impaired oxidative metabolism and calcium mishandling underlie cardiac dysfunction in a rat model of post-acute isoproterenol-induced cardiomyopathy

(2015) B. Cicero Willis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mitochondrial Mechanisms in Septic Cardiomyopathy

(2015) María Cimolai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Low Levels of Lipopolysaccharide Modulate Mitochondrial Oxygen Consumption in Skeletal Muscle

(2015) Madlyn I. Frisard et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Role of Oxidative Stress in Thyroid Hormone-Induced Cardiomyocyte Hypertrophy and Associated Cardiac Dysfunction: An Undisclosed Story

(2015) Mohammad T. Elnakish et al.   Oxidative Medicine and Cellular Longevity

Soluble Heparan Sulfate in Serum of Septic Shock Patients Induces Mitochondrial Dysfunction in Murine Cardiomyocytes

(2015) Lukas Martin et al.   SHOCK

Mitochondrial ROS Induces Cardiac Inflammation via a Pathway through mtDNA Damage in a Pneumonia-Related Sepsis Model

(2015) Xiao Yao et al.   PLoS One

Cardiac mitochondrial biogenesis in endotoxemia is not accompanied by mitochondrial function recovery

(2014) Virginia Vanasco et al.   FREE RADICAL BIOLOGY AND MEDICINE

Early levosimendan administration may improve outcome in patients with subarachnoid hemorrhage complicated by acute heart failure

(2014) John Papanikolaou et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Mechanisms of Cardiac and Renal Dysfunction in Patients Dying of Sepsis

(2013) Osamu Takasu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Endothelial NOS (NOS3) impairs myocardial function in developing sepsis

(2013) Annette M. Sandt et al.   BASIC RESEARCH IN CARDIOLOGY

Oxidative status in ICU patients with septic shock

(2013) Maria Karapetsa et al.   FOOD AND CHEMICAL TOXICOLOGY

Redox evaluation in sepsis model mice by the in vivo ESR technique using acyl-protected hydroxylamine

(2013) Shoko Okazaki et al.   FREE RADICAL BIOLOGY AND MEDICINE

Disruption of Calcium Homeostasis in Cardiomyocytes Underlies Cardiac Structural and Functional Changes in Severe Sepsis

(2013) Mara R. N. Celes et al.   PLoS One

Antioxidant N-Acetylcysteine Attenuates the Reduction of Brg1 Protein Expression in the Myocardium of Type 1 Diabetic Rats

(2013) Jinjin Xu et al.   Journal of Diabetes Research

Specific inhibition of mitochondrial oxidative stress suppresses inflammation and improves cardiac function in a rat pneumonia-related sepsis model

(2012) Qun S. Zang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

NOX1/NADPH oxidase is involved in endotoxin-induced cardiomyocyte apoptosis

(2012) Kuniharu Matsuno et al.   FREE RADICAL BIOLOGY AND MEDICINE

Free radicals and antioxidants: updating a personal view

(2012) Barry Halliwell   NUTRITION REVIEWS

Mitochondrial Fission, Fusion, and Stress

(2012) R. J. Youle et al.   SCIENCE

Structural Changes of the Heart During Severe Sepsis or Septic Shock

(2012) Lonneke Smeding et al.   SHOCK

Pathomechanisms of Myocardial Dysfunction in Sepsis

(2012) Clara Batista Lorigados et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Oxidative stress and mitochondrial dysfunction in sepsis

(2011) H.F. Galley   BRITISH JOURNAL OF ANAESTHESIA

Nitric Oxide-Derived Oxidants with a Focus on Peroxynitrite: Molecular Targets,Cellular Responses and Therapeutic Implications

(2011) P. Calcerrada et al.   CURRENT PHARMACEUTICAL DESIGN

Nitric oxide synthases: regulation and function

(2011) U. Forstermann et al.   EUROPEAN HEART JOURNAL

ROCK induced inflammation of the microcirculation during endotoxemia mediated by nitric oxide synthase

(2011) Caroline C. McGown et al.   MICROVASCULAR RESEARCH

ROS and RNS Signaling in Heart Disorders: Could Antioxidant Treatment Be Successful?

(2011) Igor Afanas'ev   Oxidative Medicine and Cellular Longevity

Mitochondrial Nitric Oxide Synthase Participates in Septic Shock Myocardial Depression by Nitric Oxide Overproduction and Mitochondrial Permeability Transition Pore Opening

(2011) Ce Xu et al.   SHOCK

Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation

(2011) Dmitri V. Krysko et al.   TRENDS IN IMMUNOLOGY

The Role of Mitochondria in Reactive Oxygen Species Metabolism and Signaling

(2010) Anatoly A. Starkov   Annals of the New York Academy of Sciences

Thrombopoietin modulates cardiac contractility in vitro and contributes to myocardial depressing activity of septic shock serum

(2010) Enrico Lupia et al.   BASIC RESEARCH IN CARDIOLOGY

Rho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarity

(2010) Mutsuki Amano et al.   Cytoskeleton

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Nitrosative protein oxidation is modulated during early endotoxemia

(2010) Joseph R. Burgoyne et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

INCREASED SARCOLEMMAL PERMEABILITY AS AN EARLY EVENT IN EXPERIMENTAL SEPTIC CARDIOMYOPATHY

(2010) Mara R.N. Celes et al.   SHOCK

Cytochrome c-induced lymphocyte death from the outside in: inhibition by serum leucine-rich alpha-2-glycoprotein-1

(2009) Ramil Codina et al.   APOPTOSIS

Energetic myocardial metabolism and oxidative stress: Let's make them our friends in the fight against heart failure

(2009) Sabino Scolletta et al.   BIOMEDICINE & PHARMACOTHERAPY

Activation of the ubiquitin proteolytic pathway in human septic heart and diaphragm

(2009) Christophe Rabuel et al.   CARDIOVASCULAR PATHOLOGY

Upregulation of Heme Oxygenase-1 in an Animal Model of Takotsubo Cardiomyopathy

(2009) Takashi Ueyama et al.   CIRCULATION JOURNAL

Oxidative stress induces degradation of mitochondrial DNA

(2009) Inna Shokolenko et al.   NUCLEIC ACIDS RESEARCH

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

(2009) S. S. Iyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Takotsubo Cardiomyopathy

(2008) Yoshihiro J. Akashi et al.   CIRCULATION

Oxidative Stress and Mitochondrial DNA Damage in Heart Failure

(2008) Hiroyuki Tsutsui et al.   CIRCULATION JOURNAL

Actual incidence of global left ventricular hypokinesia in adult septic shock

(2008) Antoine Vieillard-Baron et al.   CRITICAL CARE MEDICINE

The Microcirculation in Health and Critical Disease

(2008) Corstian A. den Uil et al.   PROGRESS IN CARDIOVASCULAR DISEASES