Specific inhibition of mitochondrial oxidative stress suppresses inflammation and improves cardiac function in a rat pneumonia-related sepsis model

Mitochondria-Targeted Antioxidants Protect Against Amyloid-β Toxicity in Alzheimer's Disease Neurons

(2017) Maria Manczak et al.   JOURNAL OF ALZHEIMERS DISEASE

Regulation of VEGF-induced endothelial cell migration by mitochondrial reactive oxygen species

(2011) Youxue Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myocardial ischemia-reperfusion

(2011) Jérémy Fauconnier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prevention of diabetic nephropathy in Ins2+/−AkitaJmice by the mitochondria-targeted therapy MitoQ

(2010) Balu K. Chacko et al.   BIOCHEMICAL JOURNAL

Novel mitochondria-targeted antioxidants, “Skulachev-Ion” derivatives, accelerate dermal wound healing in animals

(2010) I. A. Demianenko et al.   BIOCHEMISTRY-MOSCOW

Rapid uptake of lipophilic triphenylphosphonium cations by mitochondria in vivo following intravenous injection: Implications for mitochondria-specific therapies and probes

(2010) Carolyn M. Porteous et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The Autonomic Nervous System in Cardiac Electrophysiology

(2010) Suraj Kapa et al.   Cardiology in Review

Therapeutic Targeting of Mitochondrial Superoxide in Hypertension

(2010) Anna E. Dikalova et al.   CIRCULATION RESEARCH

The Surviving Sepsis Campaign: Results of an international guideline-based performance improvement program targeting severe sepsis*

(2010) Mitchell M. Levy et al.   CRITICAL CARE MEDICINE

Neuroprotection by a mitochondria-targeted drug in a Parkinson's disease model

(2010) Anamitra Ghosh et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative stress as a novel target in pediatric sepsis management

(2010) Bettina von Dessauer et al.   JOURNAL OF CRITICAL CARE

The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients

(2010) Edward J. Gane et al.   LIVER INTERNATIONAL

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Effects of the mitochondria-targeted antioxidant SkQ1 on sexually motivated behavior in male rats

(2010) Tamara G. Amstislavskaya et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

MITOCHONDRIAL DNA IS RELEASED BY SHOCK AND ACTIVATES NEUTROPHILS VIA P38 MAP KINASE

(2010) Qin Zhang et al.   SHOCK

MitoQ administration prevents endotoxin-induced cardiac dysfunction

(2009) G. S. Supinski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Doxorubicin Inactivates Myocardial Cytochrome c Oxidase in Rats: Cardioprotection by Mito-Q

(2009) Karunakaran Chandran et al.   BIOPHYSICAL JOURNAL

Age-dependent differences of interleukin-6 activity in cardiac function after burn complicated by sepsis

(2009) Lin Wang et al.   BURNS

Antioxidant Therapy in Critically Septic Patients

(2009) S. Rinaldi et al.   CURRENT DRUG TARGETS

Cardiac dysfunction in severe sepsis and septic shock

(2009) Sergio L Zanotti-Cavazzoni et al.   Current Opinion in Critical Care

The mitochondria targeted antioxidant MitoQ protects against fluoroquinolone-induced oxidative stress and mitochondrial membrane damage in human Achilles tendon cells

(2009) Damon A. Lowes et al.   FREE RADICAL RESEARCH

Oxidative Stress and Mitochondrial DNA Damage in Heart Failure

(2008) Hiroyuki Tsutsui et al.   CIRCULATION JOURNAL

The mitochondria-targeted antioxidant MitoQ protects against organ damage in a lipopolysaccharide–peptidoglycan model of sepsis

(2008) Damon A. Lowes et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nitric oxide synthase-2 induction optimizes cardiac mitochondrial biogenesis after endotoxemia

(2008) Crystal M. Reynolds et al.   FREE RADICAL BIOLOGY AND MEDICINE

Fluid resuscitation influences cardiovascular performance and mortality in a murine model of sepsis

(2008) Sergio L. Zanotti-Cavazzoni et al.   INTENSIVE CARE MEDICINE

Cardiogenic small molecules that enhance myocardial repair by stem cells

(2008) H. Sadek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondria-Targeted Cytoprotective Peptides for Ischemia–Reperfusion Injury

(2007) Hazel H. Szeto   ANTIOXIDANTS & REDOX SIGNALING

Molecular Mechanisms of Angiotensin II–Mediated Mitochondrial Dysfunction

(2007) Abdulrahman K. Doughan et al.   CIRCULATION RESEARCH