Sirt1 Protects Endothelial Cells against LPS-Induced Barrier Dysfunction

RAGE Plays a Role in LPS-Induced NF-κB Activation and Endothelial Hyperpermeability

(2017) Liqun Wang et al.   SENSORS

Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice

(2016) Natalie E. de Picciotto et al.   AGING CELL

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Polydatin Protecting Kidneys against Hemorrhagic Shock-Induced Mitochondrial DysfunctionviaSIRT1 Activation and p53 Deacetylation

(2016) Zhenhua Zeng et al.   Oxidative Medicine and Cellular Longevity

Rnd3 as a Novel Target to Ameliorate Microvascular Leakage

(2016) Jerome W. Breslin et al.   Journal of the American Heart Association

Sirtuins Link Inflammation and Metabolism

(2016) Vidula T. Vachharajani et al.   Journal of Immunology Research

AGEs-RAGE System Down-Regulates Sirt1 Through the Ubiquitin-Proteasome Pathway to Promote FN and TGF-β1 Expression in Male Rat Glomerular Mesangial Cells

(2015) Kai-Peng Huang et al.   ENDOCRINOLOGY

Polydatin protects hepatocytes against mitochondrial injury in acute severe hemorrhagic shock via SIRT1-SOD2pathway

(2015) Pengyun Li et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Resveratrol attenuates microvascular inflammation in sepsis via SIRT-1-Induced modulation of adhesion molecules inob/obmice

(2015) Xianfeng Wang et al.   Obesity

Role of Src in Vascular Hyperpermeability Induced by Advanced Glycation End Products

(2015) Weijin Zhang et al.   Scientific Reports

Acute Alcohol Intoxication-Induced Microvascular Leakage

(2014) Travis M. Doggett et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Des-acyl ghrelin protects microvascular endothelial cells from oxidative stress-induced apoptosis through sirtuin 1 signaling pathway

(2014) Takeshi Shimada et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Hemoglobin-Induced Endothelial Cell Permeability Is Controlled, in Part, via a Myeloid Differentiation Primary Response Gene–88–Dependent Signaling Mechanism

(2013) Christina Lisk et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

SIRT1 inhibits NADPH oxidase activation and protects endothelial function in the rat aorta: Implications for vascular aging

(2013) María José Zarzuelo et al.   BIOCHEMICAL PHARMACOLOGY

Constitutive excessive erythrocytosis causes inflammation and increased vascular permeability in aged mouse brain

(2013) O.O. Ogunshola et al.   BRAIN RESEARCH

Crosstalk between Oxidative Stress and SIRT1: Impact on the Aging Process

(2013) Antero Salminen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Resveratrol reduces acute lung injury in a LPS-induced sepsis mouse model via activation of Sirt1

(2013) TONGXUN LI et al.   Molecular Medicine Reports

Dichloro-dihydro-fluorescein diacetate (DCFH-DA) assay: A quantitative method for oxidative stress assessment of nanoparticle-treated cells

(2013) A. Aranda et al.   TOXICOLOGY IN VITRO

Cross-talk between SIRT1 and p66Shc in vascular diseases

(2013) Hou-Zao Chen et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Loss-of-SIRT1 function during vascular ageing: Hyperphosphorylation mediated by cyclin-dependent kinase 5

(2013) Bo Bai et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Pathophysiology of microcirculatory dysfunction and the pathogenesis of septic shock

(2013) Daniel De Backer et al.   Virulence

Alarmins: awaiting a clinical response

(2012) James K. Chan et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of sirtuin 1 activation on nicotine and lipopolysaccharide-induced cytotoxicity and inflammatory cytokine production in human gingival fibroblasts

(2012) G-J. Park et al.   JOURNAL OF PERIODONTAL RESEARCH

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(2012) Huan Yang et al.   MOLECULAR MEDICINE

Endothelium-specific SIRT1 overexpression inhibits hyperglycemia-induced upregulation of vascular cell senescence

(2012) HouZao Chen et al.   Science China-Life Sciences

RhoA-Mediated Signaling in Notch-Induced Senescence-Like Growth Arrest and Endothelial Barrier Dysfunction

(2011) Deepak Venkatesh et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Septic Shock Is Associated with Receptor for Advanced Glycation End Products Ligation of LPS

(2011) Y. Yamamoto et al.   JOURNAL OF IMMUNOLOGY

Broken Barriers: A New Take on Sepsis Pathogenesis

(2011) N. M. Goldenberg et al.   Science Translational Medicine

β-Catenin Dynamics in the Regulation of Microvascular Endothelial Cell Hyperpermeability

(2011) Binu Tharakan et al.   SHOCK

Regulation of Endothelial Permeability via Paracellular and Transcellular Transport Pathways

(2010) Yulia Komarova et al.   Annual Review of Physiology

Resveratrol induces mitochondrial biogenesis in endothelial cells

(2009) Anna Csiszar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

HMGB1 Enhances the Proinflammatory Activity of Lipopolysaccharide by Promoting the Phosphorylation of MAPK p38 through Receptor for Advanced Glycation End Products

(2009) Y.-H. Qin et al.   JOURNAL OF IMMUNOLOGY

Protein deacetylation by SIRT1: An emerging key post-translational modification in metabolic regulation

(2009) Jiujiu Yu et al.   PHARMACOLOGICAL RESEARCH

RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis

(2008) Olga Turovskaya et al.   CARCINOGENESIS

SIRT1 Redistribution on Chromatin Promotes Genomic Stability but Alters Gene Expression during Aging

(2008) Philipp Oberdoerffer et al.   CELL

Amifostine reduces lung vascular permeability via suppression of inflammatory signalling

(2008) P. Fu et al.   EUROPEAN RESPIRATORY JOURNAL

The role of p53 in brain edema after 24 h of experimental subarachnoid hemorrhage in a rat model

(2008) Junhao Yan et al.   EXPERIMENTAL NEUROLOGY

sRAGE is Elevated in Septic Patients and Associated With Patients Outcome

(2007) Christian Bopp et al.   JOURNAL OF SURGICAL RESEARCH