Resveratrol attenuates microvascular inflammation in sepsis via SIRT-1-Induced modulation of adhesion molecules inob/obmice

Sirtuin 1 stabilization by HuR represses TNF-α- and glucose-induced E-selectin release and endothelial cell adhesivenessin vitro: relevance to human metabolic syndrome

(2014) Giulio Ceolotto et al.   CLINICAL SCIENCE

Obesity and 1-Year Outcomes in Older Americans With Severe Sepsis*

(2014) Hallie C. Prescott et al.   CRITICAL CARE MEDICINE

SIRT1 inhibition during the hypoinflammatory phenotype of sepsis enhances immunity and improves outcome

(2014) Vidula T. Vachharajani et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Resveratrol ameliorates hepatic metaflammation and inhibits NLRP3 inflammasome activation

(2014) Soo Jin Yang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The Resveratrol Attenuates Ethanol-Induced Hepatocyte Apoptosis Via Inhibiting ER-Related Caspase-12 Activation and PDE Activity In Vitro

(2013) LQ Liu et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Resveratrol in metabolic health: an overview of the current evidence and perspectives

(2013) Morten Møller Poulsen et al.   Annals of the New York Academy of Sciences

Resveratrol Protects HUVECs from Oxidized-LDL Induced Oxidative Damage by Autophagy Upregulation via the AMPK/SIRT1 Pathway

(2013) Hualei Guo et al.   CARDIOVASCULAR DRUGS AND THERAPY

Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders

(2013) Anu Kauppinen et al.   CELLULAR SIGNALLING

Adipose tissue and liver expression of SIRT1, 3, and 6 increase after extensive weight loss in morbid obesity

(2013) Alexander R. Moschen et al.   JOURNAL OF HEPATOLOGY

Effects of resveratrol on obesity-related inflammation markers in adipose tissue of genetically obese rats

(2013) Saioa Gómez-Zorita et al.   NUTRITION

Biomarkers of Endothelial Cell Activation in Early Sepsis

(2013) Simon Skibsted et al.   SHOCK

Epidemiology of severe sepsis

(2013) Florian B Mayr et al.   Virulence

SIRT1 regulates TNF-α-induced expression of CD40 in 3T3-L1 adipocytes via NF-κB pathway

(2012) Qin-Qin Lin et al.   CYTOKINE

NAD+-dependent Sirtuin 1 and 6 Proteins Coordinate a Switch from Glucose to Fatty Acid Oxidation during the Acute Inflammatory Response

(2012) Tie Fu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fueling the flame: bioenergy couples metabolism and inflammation

(2012) T. F. Liu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

SIRT1 Activators Suppress Inflammatory Responses through Promotion of p65 Deacetylation and Inhibition of NF-κB Activity

(2012) Hongying Yang et al.   PLoS One

Small-Molecule Allosteric Activators of Sirtuins

(2011) David A. Sinclair et al.   Annual Review of Pharmacology and Toxicology

NAD+-dependent SIRT1 Deacetylase Participates in Epigenetic Reprogramming during Endotoxin Tolerance

(2011) Tie Fu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol improves renal microcirculation, protects the tubular epithelium, and prolongs survival in a mouse model of sepsis-induced acute kidney injury

(2011) Joseph H. Holthoff et al.   KIDNEY INTERNATIONAL

Health and economic burden of the projected obesity trends in the USA and the UK

(2011) Y Claire Wang et al.   LANCET

Adiponectin-Deficiency Exaggerates Sepsis-Induced Microvascular Dysfunction in the Mouse Brain

(2011) Vidula Vachharajani et al.   Obesity

Clinical and Economic Outcomes Attributable to Health Care–Associated Sepsis and Pneumonia

(2010) Michael R. Eber   ARCHIVES OF INTERNAL MEDICINE

Sirtuin activators: Designing molecules to extend life span

(2010) Antoni Camins et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Resveratrol Upregulated SIRT1, FOXO1, and Adiponectin and Downregulated PPARγ1–3 mRNA Expression in Human Visceral Adipocytes

(2010) Cíntia dos Santos Costa et al.   OBESITY SURGERY

Effect of obesity on intensive care morbidity and mortality: A meta-analysis*

(2009) Morohunfolu E. Akinnusi et al.   CRITICAL CARE MEDICINE

SEPSIS-INDUCED INTESTINAL MICROVASCULAR AND INFLAMMATORY RESPONSES IN OBESE MICE

(2009) Georg Singer et al.   SHOCK

Obesity Exacerbates Sepsis-Induced Inflammation and Microvascular Dysfunction in Mouse Brain

(2007) VIDULA VACHHARAJANI et al.   MICROCIRCULATION