Three-step synthesis of 2,5,7-trisubstituted indoles from N-acetyl-2,4,6-trichloroaniline using Pd-catalyzed site-selective cross-coupling

Synthetic Access to 3,5,7-Trisubstituted Indoles Enabled by Iridium­-Catalyzed C–H Borylation

(2017) Jonathan Sperry et al.   SYNTHESIS-STUTTGART

Amine Directed Pd(II)-Catalyzed C–H Activation-Intramolecular Amination of N-Het(aryl)/Acyl Enaminonitriles and Enaminones: An Approach towards Multisubstituted Indoles and Heterofused Pyrroles

(2016) Somaraju Yugandar et al.   JOURNAL OF ORGANIC CHEMISTRY

One-Pot Synthesis of Substituted Benzo[b]furans and Indoles from Dichlorophenols/Dichloroanilines Using a Palladium–Dihydroxyterphenylphosphine Catalyst

(2016) Miyuki Yamaguchi et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper Chloride-Catalyzed Aerobic Oxidative Annulation ofN-Furfuryl-β-Enaminones:Access to Polysubstituted Pyrroles and Indoles

(2015) Jianchao Liu et al.   ADVANCED SYNTHESIS & CATALYSIS

Rhodium(III)-Catalyzed Redox-Neutral CH Annulation of Arylnitrones and Alkynes for the Synthesis of Indole Derivatives

(2015) Zhi Zhou et al.   ADVANCED SYNTHESIS & CATALYSIS

A facile palladium-catalyzed route to 2,5,7-trisubstituted indoles

(2015) Sandro Cacchi et al.   TETRAHEDRON

Scalable synthesis of dihydroxyterphenylphosphine ligands

(2015) Miyuki Yamaguchi et al.   TETRAHEDRON

Indole synthesis through transition metal-catalyzed C–H activation

(2015) Tenglong Guo et al.   TETRAHEDRON LETTERS

Palladium-Catalyzed Difunctionalization of Alkynes via C–N and S–N Cleavages: A Versatile Approach to Highly Functional Indoles

(2014) Fei Zhao et al.   ORGANIC LETTERS

One-Pot Synthesis of 2,4-Disubstituted Indoles from N-Tosyl-2,3-dichloroaniline Using Palladium–Dihydroxyterphenylphosphine Catalyst

(2014) Miyuki Yamaguchi et al.   ORGANIC LETTERS

Efficient Oxidative Chlorination of Aromatics on Saturated Sodium Chloride Solution

(2013) Liuqun Gu et al.   ADVANCED SYNTHESIS & CATALYSIS

One-Pot Synthesis of Substituted Benzo[b]furans from Mono- and Dichlorophenols Using Palladium Catalysts Bearing Dihydroxyterphenylphosphine

(2013) Miyuki Yamaguchi et al.   JOURNAL OF ORGANIC CHEMISTRY

Biomedical Importance of Indoles

(2013) Nagendra Kaushik et al.   MOLECULES

Selective synthesis of indazoles and indoles via triazene–alkyne cyclization switched by different metals

(2013) Yan Fang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Oxidative para-Triflation of Acetanilides

(2013) Amélie Pialat et al.   ORGANIC LETTERS

Methylation of imidazoline related compounds leads to loss of α2-adrenoceptor affinity. Synthesis and biological evaluation of selective I1 imidazoline receptor ligands

(2012) Stephan Schann et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Progress in palladium-based catalytic systems for the sustainable synthesis of annulated heterocycles: a focus on indole backbones

(2012) Mélanie Platon et al.   CHEMICAL SOCIETY REVIEWS

General and highly efficient fluorinated-N-heterocyclic carbene–based catalysts for the palladium-catalyzed Suzuki–Miyaura reaction

(2012) Taoping Liu et al.   TETRAHEDRON

Indole synthesis – something old, something new

(2012) Martyn Inman et al.   Chemical Science

A New One-Pot Synthesis of Polysubstituted Indoles from Pyrroles and β-Nitroacrylates

(2011) Alessandro Palmieri et al.   ADVANCED SYNTHESIS & CATALYSIS

Mild CH Halogenation of Anilides and the Isolation of an Unusual Palladium(I)-Palladium(II) Species

(2011) Robin B. Bedford et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Au-catalyzed synthesis of 2-alkylindoles from N-arylhydroxylamines and terminal alkynes

(2011) Yanzhao Wang et al.   CHEMICAL COMMUNICATIONS

Update 1 of: Synthesis and Functionalization of Indoles Through Palladium-Catalyzed Reactions

(2011) Sandro Cacchi et al.   CHEMICAL REVIEWS

Approaches to the Synthesis of 2,3-Dihaloanilines. Useful Precursors of 4-Functionalized-1H-indoles

(2011) Verónica Guilarte et al.   JOURNAL OF ORGANIC CHEMISTRY

A Facile Route to Polysubstituted Indoles via Three-Component Reaction of 2-Ethynylaniline, Sulfonyl Azide, and Nitroolefin

(2011) Zhiyuan Chen et al.   ORGANIC LETTERS

Hydroxylated terphenylphosphine ligands for palladium-catalyzed ortho-selective cross-coupling of dibromophenols, dibromoanilines, and their congeners with Grignard reagents

(2011) Shunpei Ishikawa et al.   TETRAHEDRON

Site-Selective Cross-Coupling of Dichlorinated Benzo-Fused Nitrogen-Heterocycles with Grignard Reagents

(2010) Hideyuki Konishi et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Marine Indole Alkaloids: Potential New Drug Leads for the Control of Depression and Anxiety

(2010) Anna J. Kochanowska-Karamyan et al.   CHEMICAL REVIEWS

Hydroxyterphenylphoshine−Palladium Catalyst for Benzo[b]furan Synthesis from 2-Chlorophenols. Bifunctional Ligand Strategy for Cross-Coupling of Chloroarenes

(2010) Jia-Rui Wang et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of 4-functionalized-1H-indoles from 2,3-dihalophenols

(2010) Roberto Sanz et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Efficient Pd-Catalyzed Amination Reactions for Heterocycle Functionalization

(2010) Jaclyn L. Henderson et al.   ORGANIC LETTERS

DHTP Ligands for the Highly Ortho-Selective, Palladium-Catalyzed Cross-Coupling of Dihaloarenes with Grignard Reagents: A Conformational Approach for Catalyst Improvement

(2009) Shunpei Ishikawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances in the application of the Sonogashira method in the synthesis of heterocyclic compounds

(2009) Majid M. Heravi et al.   TETRAHEDRON

Synthesis of hydroxylated oligoarene-type phosphines by a repetitive two-step method

(2009) Shunpei Ishikawa et al.   TETRAHEDRON

A one-pot procedure for trifluoroacetylation of arylamines using trifluoroacetic acid as a trifluoroacetylating reagent

(2009) Junpei Ohtaka et al.   TETRAHEDRON LETTERS

Oligoarenes as molecular backbones of catalysts: synthesis and applications

(2008) Kei Manabe et al.   CHEMICAL COMMUNICATIONS

A New Class of Easily Activated Palladium Precatalysts for Facile C−N Cross-Coupling Reactions and the Low Temperature Oxidative Addition of Aryl Chlorides

(2008) Mark R. Biscoe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Simple Indole Synthesis by One-Pot Sonogashira Coupling-NaOH-Mediated Cyclization

(2008) Roberto Sanz et al.   SYNLETT

A convenient synthesis of pyrrolopyridines and 2-substituted indoles by gold-catalyzed cycloisomerization

(2008) K.C. Majumdar et al.   TETRAHEDRON LETTERS