Copper promoted N-alkylation of sulfoximines with alkylboronic acid under mild conditions

Sulfoximines from a Medicinal Chemist's Perspective: Physicochemical and in vitro Parameters Relevant for Drug Discovery

(2017) Marcus Frings et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Therapeutic effects of methionine sulfoximine in multiple diseases include and extend beyond inhibition of glutamine synthetase

(2017) William S. A. Brusilow et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Copper-catalyzed oxidative decarboxylative coupling of α-keto acids and sulfoximines

(2017) Chaleena Pimpasri et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Access to N-cyanosulfoximines by transition metal-free iminations of sulfoxides

(2017) C. A. Dannenberg et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Ruthenium(II)-Catalyzed C–H Oxygenations of Reusable Sulfoximine Benzamides

(2017) Keshav Raghuvanshi et al.   ORGANIC LETTERS

Ruthenium-Catalyzed Hydroarylation and One-Pot Twofold Unsymmetrical C−H Functionalization of Arenes

(2016) Koushik Ghosh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-catalyzed N-thioetherification of sulfoximines using disulfides

(2016) Hui Zhu et al.   CHEMICAL COMMUNICATIONS

Copper-Catalyzed Amidation of Primary and Secondary Alkyl Boronic Esters

(2016) Luis M. Mori-Quiroz et al.   CHEMISTRY-A EUROPEAN JOURNAL

The “Cyclopropyl Fragment” is a Versatile Player that Frequently Appears in Preclinical/Clinical Drug Molecules

(2016) Tanaji T. Talele   JOURNAL OF MEDICINAL CHEMISTRY

Copper-catalyzed oxidative C(sp3)–H/N–H coupling of sulfoximines and amides with simple alkanes via a radical process

(2015) Fan Teng et al.   CHEMICAL COMMUNICATIONS

Iron-Catalyzed Acylative Dealkylation ofN-Alkylsulfoximines

(2015) Philip Lamers et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Aerobic Copper-Catalyzed O-Methylation with Methylboronic Acid

(2015) Clare E. Jacobson et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper-catalyzed N-methylation/ethylation of sulfoximines

(2015) Fan Teng et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Silver-Mediated N-Trifluoromethylation of Sulfoximines

(2015) Fan Teng et al.   ORGANIC LETTERS

Methionine and Buthionine Sulfoximines: Syntheses under Mild and Safe Imidation/Oxidation Conditions

(2014) Laura Buglioni et al.   ADVANCED SYNTHESIS & CATALYSIS

N-Alkylations ofNH-Sulfoximines andNH-Sulfondiimines with Alkyl Halides Mediated by Potassium Hydroxide in Dimethyl Sulfoxide

(2014) Christine M. M. Hendriks et al.   ADVANCED SYNTHESIS & CATALYSIS

A copper-mediated oxidative N-cyanation reaction

(2014) Fan Teng et al.   CHEMICAL COMMUNICATIONS

Fluorinated sulfoximines: syntheses, properties and applications

(2014) Vincent Bizet et al.   CHEMICAL SOCIETY REVIEWS

Hydroarylations of Heterobicyclic Alkenes through Rhodium-Catalyzed Directed CH Functionalizations of S-Aryl Sulfoximines

(2014) Wanrong Dong et al.   CHEMISTRY-A EUROPEAN JOURNAL

General synthetic strategies towards N-alkyl sulfoximine building blocks for medicinal chemistry and the use of dimethylsulfoximine as a versatile precursor

(2014) Frederick W. Goldberg et al.   TETRAHEDRON

Sulfoximines: A Neglected Opportunity in Medicinal Chemistry

(2013) Ulrich Lücking   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Oxidative Cross-Coupling of Sulfoximines and Alkynes

(2013) Long Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Primary Alkylboronic Acids as Highly Active Catalysts for the Dehydrative Amide Condensation of α-Hydroxycarboxylic Acids

(2013) Risa Yamashita et al.   ORGANIC LETTERS

Copper-Catalyzed N- and O-Alkylation of Amines and Phenols using Alkylborane Reagents

(2013) Shunsuke Sueki et al.   ORGANIC LETTERS

Selective Formation of Secondary Amides via the Copper-Catalyzed Cross-Coupling of Alkylboronic Acids with Primary Amides

(2013) Steven A. Rossi et al.   ORGANIC LETTERS

Synthesis of chiral sulfoximine-based thioureas and their application in asymmetric organocatalysis

(2012) Marcus Frings et al.   Beilstein Journal of Organic Chemistry

N,N-Dimethyl-S-difluoromethyl-S-phenylsulfoximinium tetrafluoroborate: A versatile electrophilic difluoromethylating reagent

(2011) G.K. Surya Prakash et al.   JOURNAL OF FLUORINE CHEMISTRY

Copper-promoted N-cyclopropylation of anilines and amines by cyclopropylboronic acid

(2010) Sébastien Bénard et al.   CHEMICAL COMMUNICATIONS

Synthesis of Phosphanyl Sulfoximines Through Phospha-Michael Reaction of Alkenyl Sulfoximines and Their Evaluation as Chiral Bidentate 1,5-N,P Ligands for Palladium in Asymmetric Allylic Alkylation

(2010) Fabien Lemasson et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity

(2009) Daniel P. Walker et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Selective Monomethylation of Anilines by Cu(OAc)2-Promoted Cross-Coupling with MeB(OH)2

(2009) Israel González et al.   ORGANIC LETTERS

Fluorinated Johnson Reagent for Transfer-Trifluoromethylation to Carbon Nucleophiles

(2008) Shun Noritake et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

N-Cyclopropylation of Indoles and Cyclic Amides with Copper(II) Reagent

(2008) Takayuki Tsuritani et al.   ORGANIC LETTERS