Carbonylation as a novel method for the assembly of pyrazine based oligoamide alpha-helix mimetics

Synthesis of highly functionalized oligobenzamide proteomimetic foldamers by late stage introduction of sensitive groups

(2016) George M. Burslem et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Low-cost instant CO generation at room temperature using formic acid, mesyl chloride and triethylamine

(2016) Cedrick Veryser et al.   Reaction Chemistry & Engineering

Synthesis and screening of small-molecule α-helix mimetic libraries targeting protein–protein interactions

(2015) Heejo Moon et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

How Beyond Rule of 5 Drugs and Clinical Candidates Bind to Their Targets

(2015) Bradley C. Doak et al.   JOURNAL OF MEDICINAL CHEMISTRY

Amphiphilic oligoamide α-helix peptidomimetics inhibit islet amyloid polypeptide aggregation

(2015) Oleg V. Kulikov et al.   TETRAHEDRON LETTERS

Stereocontrolled protein surface recognition using chiral oligoamide proteomimetic foldamers

(2015) Valeria Azzarito et al.   Chemical Science

Design, synthesis and conformational analyses of bifacial benzamide based foldamers

(2015) Silvia Rodriguez-Marin et al.   RSC Advances

Small-Molecule Inhibitors of Protein-Protein Interactions: Progressing toward the Reality

(2014) Michelle R. Arkin et al.   CHEMISTRY & BIOLOGY

Targeting Protein-Protein Interaction by Small Molecules

(2013) Lingyan Jin et al.   Annual Review of Pharmacology and Toxicology

α-Helix mimetics: Outwards and upwards

(2013) Madura K.P. Jayatunga et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Solid-Phase Methodology for Synthesis ofO-Alkylated Aromatic Oligoamide Inhibitors of α-Helix-Mediated Protein-Protein Interactions

(2013) Natasha S. Murphy et al.   CHEMISTRY-A EUROPEAN JOURNAL

Protein Interface Pharmacophore Mapping Tools for Small Molecule Protein: Protein Interaction Inhibitor Discovery

(2013) Arnout Voet et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Design and Synthesis of Oligoamide-Based Double α-Helix Mimetics

(2013) Oleg V. Kulikov et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Aromatic Oligoamide Foldamers with a “Wet Edge” as Inhibitors of the α-Helix-Mediated p53-hDM2 Protein-Protein Interaction

(2013) Panchami Prabhakaran et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Inhibition of α-helix-mediated protein–protein interactions using designed molecules

(2013) Valeria Azzarito et al.   Nature Chemistry

Evaluating minimalist mimics by exploring key orientations on secondary structures (EKOS)

(2013) Dongyue Xin et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Studies on the Regioselective Nucleophilic Aromatic Substitution (SNAr) Reaction of 2-Substituted 3,5-Dichloropyrazines

(2013) Stephanie Scales et al.   ORGANIC LETTERS

Peptidomimetic targeting of critical androgen receptor–coregulator interactions in prostate cancer

(2013) Preethi Ravindranathan et al.   Nature Communications

An Anthraquinone Scaffold for Putative, Two-Face Bim BH3 α-Helix Mimic

(2012) Zhichao Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Relaxation of the rigid backbone of an oligoamide-foldamer-based α-helix mimetic: identification of potent Bcl-xL inhibitors

(2012) Jeremy L. Yap et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

2-O-Alkylated para-benzamide α-helix mimetics: the role of scaffold curvature

(2012) Valeria Azzarito et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of the novel trimeric benzamides—potential inhibitors of protein–protein interactions

(2012) Oleg V. Kulikov et al.   RSC Advances

Assessing Helical Protein Interfaces for Inhibitor Design

(2011) Brooke N. Bullock et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ex Situ Generation of Stoichiometric and Substoichiometric 12CO and 13CO and Its Efficient Incorporation in Palladium Catalyzed Aminocarbonylations

(2011) Philippe Hermange et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-alkylated oligoamide α-helical proteomimetics

(2010) Frederick Campbell et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Palladium-Catalyzed Carbonylation Reactions of Aryl Halides and Related Compounds

(2009) Anne Brennführer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Novel Amphiphilic α-Helix Mimetics Based on a Bis-benzamide Scaffold

(2009) Srinivasa Marimganti et al.   ORGANIC LETTERS

Controlling Curvature in a Family of Oligoamide α-Helix Mimetics

(2008) Ishu Saraogi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Carbonylation Reactions of Aryl Bromides at Atmospheric Pressure: A General System Based on Xantphos

(2008) Joseph R. Martinelli et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of functionalised aromatic oligamide rods

(2007) Jeffrey Plante et al.   ORGANIC & BIOMOLECULAR CHEMISTRY