Relaxation of the rigid backbone of an oligoamide-foldamer-based α-helix mimetic: identification of potent Bcl-xL inhibitors

Helix-mediated protein–protein interactions as targets for intervention using foldamers

(2011) Thomas A. Edwards et al.   AMINO ACIDS

MiR-148a promotes apoptosis by targeting Bcl-2 in colorectal cancer

(2011) H Zhang et al.   CELL DEATH AND DIFFERENTIATION

Ortho-selectivity in the nucleophilic aromatic substitution (SNAr) reactions of 3-substituted, 2,6-dichloropyridines with alkali metal alkoxides

(2011) Jeremy L. Yap et al.   TETRAHEDRON LETTERS

Disrupting protein–protein interactions with non-peptidic, small molecule α-helix mimetics

(2010) Christopher G Cummings et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Mcl-1 is critical for survival in a subgroup of non-small-cell lung cancer cell lines

(2010) H Zhang et al.   ONCOGENE

N-alkylated oligoamide α-helical proteomimetics

(2010) Frederick Campbell et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Up-Regulation of Bcl-xl by Hepatocyte Growth Factor in Human Mesothelioma Cells Involves ETS Transcription Factors

(2009) Xiaobo Cao et al.   AMERICAN JOURNAL OF PATHOLOGY

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Apogossypol derivatives as antagonists of antiapoptotic Bcl-2 family proteins

(2009) J. Wei et al.   MOLECULAR CANCER THERAPEUTICS

Novel Amphiphilic α-Helix Mimetics Based on a Bis-benzamide Scaffold

(2009) Srinivasa Marimganti et al.   ORGANIC LETTERS

Controlling Curvature in a Family of Oligoamide α-Helix Mimetics

(2008) Ishu Saraogi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bcl-2 inhibitors: small molecules with a big impact on cancer therapy

(2008) M Vogler et al.   CELL DEATH AND DIFFERENTIATION

Acylpyrogallols as Inhibitors of Antiapoptotic Bcl-2 Proteins

(2008) Guozhi Tang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Bcl-2 family proteins and cancer

(2008) K W Yip et al.   ONCOGENE

Synthesis and Structure of 1,4-Dipiperazino Benzenes:  Chiral Terphenyl-type Peptide Helix Mimetics

(2008) Prantik Maity et al.   ORGANIC LETTERS

Synthesis and Biological Evaluation of a 5-6-5 Imidazole-Phenyl-Thiazole Based α-Helix Mimetic

(2008) Christopher G. Cummings et al.   ORGANIC LETTERS

Synthesis of functionalised aromatic oligamide rods

(2007) Jeffrey Plante et al.   ORGANIC & BIOMOLECULAR CHEMISTRY