The role of canonical and non-canonical Hedgehog signaling in tumor progression in a mouse model of small cell lung cancer

Hedgehog Signal Transduction: Key Players, Oncogenic Drivers, and Cancer Therapy

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PP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells

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From Mice to Men and Back: An Assessment of Preclinical Model Systems for the Study of Lung Cancers

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NFIB overexpression cooperates with Rb/p53 deletion to promote small cell lung cancer

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The Comparative Pathology of Genetically Engineered Mouse Models for Neuroendocrine Carcinomas of the Lung

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Recombinase-based conditional and reversible gene regulation via XTR alleles

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Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis

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Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma

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Genetic and Clonal Dissection of Murine Small Cell Lung Carcinoma Progression by Genome Sequencing

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Partial inhibition of Cdk1 in G2phase overrides the SAC and decouples mitotic events

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PTEN Is a Potent Suppressor of Small Cell Lung Cancer

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Cyclin B2 and p53 control proper timing of centrosome separation

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A centrosomal route for cancer genome instability

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Chromosomal instability causes sensitivity to metabolic stress

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Chromosomal instability and transcriptome dynamics in cancer

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Chromosomal instability (CIN): what it is and why it is crucial to cancer evolution

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A Transcriptional and Metabolic Signature of Primary Aneuploidy Is Present in Chromosomally Unstable Cancer Cells and Informs Clinical Prognosis

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Unraveling the therapeutic potential of the Hedgehog pathway in cancer

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The mechanisms of Hedgehog signalling and its roles in development and disease

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Chromosomal instability and aneuploidy in cancer: from yeast to man

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Patched dependence receptor triggers apoptosis through ubiquitination of caspase-9

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Hedgehog Overexpression Is Associated with Stromal Interactions and Predicts for Poor Outcome in Breast Cancer

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Mechanisms of Hedgehog signalling in cancer

(2011) Kieren D. Marini et al.   GROWTH FACTORS

A crucial requirement for Hedgehog signaling in small cell lung cancer

(2011) Kwon-Sik Park et al.   NATURE MEDICINE

Aberrant Epithelial–Mesenchymal Hedgehog Signaling Characterizes Barrett's Metaplasia

(2010) David H. Wang et al.   GASTROENTEROLOGY

Identification of the cell lineage at the origin of basal cell carcinoma

(2010) Khalil Kass Youssef et al.   NATURE CELL BIOLOGY

Primary cilia can both mediate and suppress Hedgehog pathway–dependent tumorigenesis

(2009) Sunny Y Wong et al.   NATURE MEDICINE

Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase

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Defining ‘chromosomal instability’

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