SALL4 promotes glycolysis and chromatin remodeling via modulating HP1α-Glut1 pathway

Knockdown of SALL4 inhibits the proliferation and reverses the resistance of MCF-7/ADR cells to doxorubicin hydrochloride

(2016) Yuan-Yuan Chen et al.   BMC MOLECULAR BIOLOGY

SALL4 is a marker of poor prognosis in serous ovarian carcinoma promoting invasion and metastasis

(2016) MENGYUAN YANG et al.   ONCOLOGY REPORTS

Oncogenic protein SALL4 and ZNF217 as prognostic indicators in solid cancers: a meta‑analysis of individual studies

(2016) Ji Cheng et al.   Oncotarget

Significance of SALL4 as a drug-resistant factor in lung cancer

(2015) NOZOMI YANAGIHARA et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Stemness factor Sall4 is required for DNA damage response in embryonic stem cells

(2015) Jianhua Xiong et al.   JOURNAL OF CELL BIOLOGY

Glycolytic metabolism influences global chromatin structure

(2015) Xue-Song Liu et al.   Oncotarget

SALL4 as an Epithelial-Mesenchymal Transition and Drug Resistance Inducer through the Regulation of c-Myc in Endometrial Cancer

(2015) Lei Liu et al.   PLoS One

SALL4 Expression in Germ Cell and Non–Germ Cell Tumors

(2014) Markku Miettinen et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma

(2014) Soufiane Boumahdi et al.   NATURE

p53 induces skin aging by depleting Blimp1+ sebaceous gland cells

(2014) J Kim et al.   Cell Death & Disease

Drug Resistance in Cancer: An Overview

(2014) Genevieve Housman et al.   Cancers

The ATM protein kinase: regulating the cellular response to genotoxic stress and more

(2013) Yosef Shiloh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis

(2013) X Lu et al.   ONCOGENE

SALL4, a novel marker for human gastric carcinogenesis and metastasis

(2013) L Zhang et al.   ONCOGENE

SALL4 is a new target in endometrial cancer

(2013) A Li et al.   ONCOGENE

Beyond the histone tail

(2013) Diego Molina-Serrano et al.   Nucleus

Sal-like protein 4 (SALL4), a stem cell biomarker in liver cancers

(2012) Tsunekazu Oikawa et al.   HEPATOLOGY

Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression

(2012) Tom Latham et al.   NUCLEIC ACIDS RESEARCH

Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1

(2011) Weibo Luo et al.   CELL

Modulation of Glucose Transporter 1 (GLUT1) Expression Levels Alters Mouse Mammary Tumor Cell Growth In Vitro and In Vivo

(2011) Christian D. Young et al.   PLoS One

Coexpression of Oct4 and Nanog Enhances Malignancy in Lung Adenocarcinoma by Inducing Cancer Stem Cell-Like Properties and Epithelial-Mesenchymal Transdifferentiation

(2010) S.-H. Chiou et al.   CANCER RESEARCH

The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α

(2010) Lei Zhong et al.   CELL

Methylated H3K4, a Transcription-Associated Histone Modification, Is Involved in the DNA Damage Response Pathway

(2010) David Faucher et al.   PLoS Genetics

PTEN/PI3K/Akt Pathway Regulates the Side Population Phenotype and ABCG2 Activity in Glioma Tumor Stem-like Cells

(2009) Anne-Marie Bleau et al.   Cell Stem Cell

Stem Cell Factor SALL4 Represses the Transcriptions of PTEN and SALL1 through an Epigenetic Repressor Complex

(2009) Jiayun Lu et al.   PLoS One

ATM Signaling Facilitates Repair of DNA Double-Strand Breaks Associated with Heterochromatin

(2008) Aaron A. Goodarzi et al.   MOLECULAR CELL

Activation of ATM depends on chromatin interactions occurring before induction of DNA damage

(2008) Yong-Chul Kim et al.   NATURE CELL BIOLOGY

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

(2008) Ittai Ben-Porath et al.   NATURE GENETICS