Sal-like protein 4 (SALL4), a stem cell biomarker in liver cancers

α-Fetoprotein–producing gastric carcinoma and combined hepatocellular and cholangiocarcinoma show similar morphology but different histogenesis with respect to SALL4 expression

(2012) Hiroko Ikeda et al.   HUMAN PATHOLOGY

The biliary tree—a reservoir of multipotent stem cells

(2012) Vincenzo Cardinale et al.   Nature Reviews Gastroenterology & Hepatology

SALL4 is a robust stimulator for the expansion of hematopoietic stem cells

(2011) J. R. Aguila et al.   BLOOD

Multipotent stem/progenitor cells in human biliary tree give rise to hepatocytes, cholangiocytes, and pancreatic islets

(2011) Vincenzo Cardinale et al.   HEPATOLOGY

SALL4, a Stem Cell Factor, Affects the Side Population by Regulation of the ATP-Binding Cassette Drug Transport Genes

(2011) Ha-Won Jeong et al.   PLoS One

Genetics of Hepatobiliary Carcinogenesis

(2011) Jean-Charles Nault et al.   SEMINARS IN LIVER DISEASE

SALL4 Represents Fetal Gut Differentiation of Gastric Cancer, and is Diagnostically Useful in Distinguishing Hepatoid Gastric Carcinoma From Hepatocellular Carcinoma

(2010) Tetsuo Ushiku et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Oncostatin M Renders Epithelial Cell Adhesion Molecule–Positive Liver Cancer Stem Cells Sensitive to 5-Fluorouracil by Inducing Hepatocytic Differentiation

(2010) Taro Yamashita et al.   CANCER RESEARCH

High expression levels of putative hepatic stem/progenitor cell biomarkers related to tumour angiogenesis and poor prognosis of hepatocellular carcinoma

(2010) X.-R. Yang et al.   GUT

Paracrine signals from mesenchymal cell populations govern the expansion and differentiation of human hepatic stem cells to adult liver fates

(2010) Yunfang Wang et al.   HEPATOLOGY

CD13 is a therapeutic target in human liver cancer stem cells

(2010) Naotsugu Haraguchi et al.   JOURNAL OF CLINICAL INVESTIGATION

Epigenetic regulation of cancer stem cells in liver cancer: Current concepts and clinical implications

(2010) J.U. Marquardt et al.   JOURNAL OF HEPATOLOGY

A Novel SALL4/OCT4 Transcriptional Feedback Network for Pluripotency of Embryonic Stem Cells

(2010) Jianchang Yang et al.   PLoS One

SALL4 is a novel sensitive and specific marker for metastatic germ cell tumors, with particular utility in detection of metastatic yolk sac tumors

(2009) Dengfeng Cao et al.   CANCER

Genetic Reconstruction of Mouse Spermatogonial Stem Cell Self-Renewal In Vitro by Ras-Cyclin D2 Activation

(2009) Jiyoung Lee et al.   Cell Stem Cell

Signal transducer and activator of transcription 3 is a transcriptional factor regulating the gene expression of SALL4

(2009) J. Dien Bard et al.   FASEB JOURNAL

Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts

(2009) Noriko Tsubooka et al.   GENES TO CELLS

Sall4Is Essential for Stabilization, But Not for Pluripotency, of Embryonic Stem Cells by Repressing Aberrant Trophectoderm Gene Expression

(2009) Shunsuke Yuri et al.   STEM CELLS

SALL4 is a key regulator of survival and apoptosis in human leukemic cells

(2008) J. Yang et al.   BLOOD

Significance of CD90+ Cancer Stem Cells in Human Liver Cancer

(2008) Zhen Fan Yang et al.   CANCER CELL

EpCAM and  -Fetoprotein Expression Defines Novel Prognostic Subtypes of Hepatocellular Carcinoma

(2008) T. Yamashita et al.   CANCER RESEARCH

Sall4 Regulates Distinct Transcription Circuitries in Different Blastocyst-Derived Stem Cell Lineages

(2008) Chin Yan Lim et al.   Cell Stem Cell

Sall4 Regulates Cell Fate Decision in Fetal Hepatic Stem/Progenitor Cells

(2008) Tsunekazu Oikawa et al.   GASTROENTEROLOGY

EpCAM-Positive Hepatocellular Carcinoma Cells Are Tumor-Initiating Cells With Stem/Progenitor Cell Features

(2008) Taro Yamashita et al.   GASTROENTEROLOGY

Differentiation therapy of hepatocellular carcinoma in mice with recombinant adenovirus carrying hepatocyte nuclear factor-4α gene

(2008) Chuan Yin et al.   HEPATOLOGY

Liver stem cells and hepatocellular carcinoma

(2008) Lopa Mishra et al.   HEPATOLOGY

The stem cell niche of human livers: Symmetry between development and regeneration

(2008) Lili Zhang et al.   HEPATOLOGY

Molecular targeted therapies in hepatocellular carcinoma

(2008) Josep M. Llovet et al.   HEPATOLOGY

High-Efficiency Stem Cell Fusion-Mediated Assay Reveals Sall4 as an Enhancer of Reprogramming

(2008) Connie C. Wong et al.   PLoS One