Targeting prohibitins with chemical ligands inhibits KRAS-mediated lung tumours
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Title
Targeting prohibitins with chemical ligands inhibits KRAS-mediated lung tumours
Authors
Keywords
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Journal
ONCOGENE
Volume 36, Issue 33, Pages 4778-4789
Publisher
Springer Nature
Online
2017-04-17
DOI
10.1038/onc.2017.93
References
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Related references
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- A RAS Renaissance: Emerging Targeted Therapies for KRAS-Mutated Non-Small Cell Lung Cancer
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- Prohibitins function as endogenous ligands for Siglec-9 and negatively regulate TCR signaling upon ligation
- (2013) Hajime Yurugi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Effects of Raf Dimerization and Its Inhibition on Normal and Disease-Associated Raf Signaling
- (2013) Alyson K. Freeman et al. MOLECULAR CELL
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- (2012) Gernot Polier et al. CHEMISTRY & BIOLOGY
- Raf activation by Ras and promotion of cellular metastasis require phosphorylation of prohibitin in the raft domain of the plasma membrane
- (2012) C-F Chiu et al. ONCOGENE
- c-Raf, but Not B-Raf, Is Essential for Development of K-Ras Oncogene-Driven Non-Small Cell Lung Carcinoma
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- (2011) Julian Downward NATURE MEDICINE
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- Regulation of RAF Activity by 14-3-3 Proteins
- (2008) Andreas Fischer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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