FTO Gene Affects Obesity and Breast Cancer Through Similar Mechanisms: A New Insight into the Molecular Therapeutic Targets

AMPK regulates lipid accumulation in skeletal muscle cells through FTO-dependent demethylation of N6-methyladenosine

(2017) Weiche Wu et al.   Scientific Reports

FTO Obesity Variant Circuitry and Adipocyte Browning in Humans

(2015) Melina Claussnitzer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Fat mass- and obesity-associated gene Fto affects the dietary response in mouse white adipose tissue

(2015) Justiina Ronkainen et al.   Scientific Reports

FTO and Obesity: Mechanisms of Association

(2014) Xu Zhao et al.   Current Diabetes Reports

Single nucleotide polymorphisms of the FTO gene and cancer risk: an overview

(2014) Marta Elena Hernández-Caballero et al.   MOLECULAR BIOLOGY REPORTS

Obesity-associated variants within FTO form long-range functional connections with IRX3

(2014) Scott Smemo et al.   NATURE

Interaction between obesity-related genes, FTO and MC4R, associated to an increase of breast cancer risk

(2013) Patrícia Amorim da Cunha et al.   MOLECULAR BIOLOGY REPORTS

Role for the obesity-related FTO gene in the cellular sensing of amino acids

(2013) P. Gulati et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FTO Genotype and 2-Year Change in Body Composition and Fat Distribution in Response to Weight-Loss Diets: The POUNDS LOST Trial

(2012) X. Zhang et al.   DIABETES

The role of the fat mass and obesity associated gene (FTO) in breast cancer risk

(2011) Virginia Kaklamani et al.   BMC Medical Genetics

Lifestyle Interaction With Fat Mass and Obesity-Associated (FTO) Genotype and Risk of Obesity in Apparently Healthy U.S. Women

(2011) T. Ahmad et al.   DIABETES CARE

Influence of genomic variation in FTO at 16q12.2, MC4R at 18q22 and NRXN3 at 14q31 genes on breast cancer risk

(2011) Renata Kusinska et al.   MOLECULAR BIOLOGY REPORTS

The common rs9939609 variant of the fat mass and obesity-associated gene is associated with obesity risk in children and adolescents of Beijing, China

(2010) Bo Xi et al.   BMC Medical Genetics

Transforming Properties of 8p11-12 Amplified Genes in Human Breast Cancer

(2010) Z.-Q. Yang et al.   CANCER RESEARCH

Expression Studies of the Obesity Candidate GeneFTOin Pig

(2009) Majbritt Busk Madsen et al.   ANIMAL BIOTECHNOLOGY

Regulation and Function of FTO mRNA Expression in Human Skeletal Muscle and Subcutaneous Adipose Tissue

(2009) L. G. Grunnet et al.   DIABETES

Inactivation of the Fto gene protects from obesity

(2009) Julia Fischer et al.   NATURE

A crucial role for adipose tissue p53 in the regulation of insulin resistance

(2009) Tohru Minamino et al.   NATURE MEDICINE

The Common Variant in theFTOGene Did Not Modify the Effect of Lifestyle Changes on Body Weight: The Finnish Diabetes Prevention Study

(2009) Tiina J. Lappalainen et al.   Obesity

Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3

(2009) A. Ragvin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physical Activity and the Association of Common FTO Gene Variants With Body Mass Index and Obesity

(2008) Evadnie Rampersaud et al.   ARCHIVES OF INTERNAL MEDICINE

Inverse relationship between obesity and FTO gene expression in visceral adipose tissue in humans

(2008) N. Klöting et al.   DIABETOLOGIA

The Obesity Gene, FTO, Is of Ancient Origin, Up-Regulated during Food Deprivation and Expressed in Neurons of Feeding-Related Nuclei of the Brain

(2008) Robert Fredriksson et al.   ENDOCRINOLOGY

The FTO Obesity Gene. Genotyping and Gene Expression Analysis in Morbidly Obese Patients

(2008) Carina Zabena et al.   OBESITY SURGERY