Eicosapentaenoic acid shows anti-inflammatory effect via GPR120 in 3T3-L1 adipocytes and attenuates adipose tissue inflammation in diet-induced obese mice

A novel anti-inflammatory role of GPR120 in intestinal epithelial cells

(2016) Arivarasu N. Anbazhagan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Adipose tissue macrophages: going off track during obesity

(2016) Lily Boutens et al.   DIABETOLOGIA

The pro-/anti-inflammatory effects of different fatty acids on visceral adipocytes are partially mediated by GPR120

(2016) Francisca Rodriguez-Pacheco et al.   EUROPEAN JOURNAL OF NUTRITION

EPA prevents fat mass expansion and metabolic disturbances in mice fed with a Western diet

(2016) Alexandre Pinel et al.   JOURNAL OF LIPID RESEARCH

Eicosapentaenoic acid promotes mitochondrial biogenesis and beige-like features in subcutaneous adipocytes from overweight subjects

(2016) L.M. Laiglesia et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

GPR120 promotes adipogenesis through intracellular calcium and extracellular signal-regulated kinase 1/2 signal pathway

(2016) Tongxing Song et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Different Effects of Eicosapentaenoic and Docosahexaenoic Acids on Atherogenic High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice

(2016) Noriko Suzuki-Kemuriyama et al.   PLoS One

Fish oil intake induces UCP1 upregulation in brown and white adipose tissue via the sympathetic nervous system

(2015) Minji Kim et al.   Scientific Reports

What We Talk About When We Talk About Fat

(2014) Evan D. Rosen et al.   CELL

Dietary Sugar and Body Weight: Have We Reached a Crisis in the Epidemic of Obesity and Diabetes?

(2014) George A. Bray et al.   DIABETES CARE

Eicosapentaenoic acid suppresses palmitate-induced cytokine production by modulating long-chain acyl-CoA synthetase 1 expression in human THP-1 macrophages

(2013) Masanori Nakakuki et al.   ATHEROSCLEROSIS

Apolipoprotein AI and High-Density Lipoprotein Have Anti-Inflammatory Effects on Adipocytes via Cholesterol Transporters

(2013) Tomio Umemoto et al.   CIRCULATION RESEARCH

Omega-3 Fatty Acids Reduce Adipose Tissue Macrophages in Human Subjects With Insulin Resistance

(2013) M. Spencer et al.   DIABETES

Palmitate-induced Activation of Mitochondrial Metabolism Promotes Oxidative Stress and Apoptosis in H4IIEC3 Rat Hepatocytes

(2013) Robert A. Egnatchik et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The Eicosapentaenoic Acid Metabolite 15-Deoxy-δ12,14-Prostaglandin J3 Increases Adiponectin Secretion by Adipocytes Partly via a PPARγ-Dependent Mechanism

(2013) Jennifer Lefils-Lacourtablaise et al.   PLoS One

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

Saturated Fatty Acid and TLR Signaling Link β Cell Dysfunction and Islet Inflammation

(2012) Kosei Eguchi et al.   Cell Metabolism

‘Metabolically healthy obesity’: Origins and implications

(2012) Gerald V. Denis et al.   MOLECULAR ASPECTS OF MEDICINE

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Saturated Fatty Acids Induce c-Src Clustering within Membrane Subdomains, Leading to JNK Activation

(2011) Ryan G. Holzer et al.   CELL

Telmisartan Improves Insulin Resistance and Modulates Adipose Tissue Macrophage Polarization in High-Fat-Fed Mice

(2011) Shiho Fujisaka et al.   ENDOCRINOLOGY

Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases

(2011) Saswata Talukdar et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Insulin-sensitive obesity

(2010) Nora Klöting et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects

(2010) Da Young Oh et al.   CELL

Sugar-Sweetened Beverages, Obesity, Type 2 Diabetes Mellitus, and Cardiovascular Disease Risk

(2010) Vasanti S. Malik et al.   CIRCULATION

Antiobesity Effect of Eicosapentaenoic Acid in High-Fat/High-Sucrose Diet-Induced Obesity: Importance of Hepatic Lipogenesis

(2010) A. Sato et al.   DIABETES

Establishment of a concept of visceral fat syndrome and discovery of adiponectin

(2010) Yuji MATSUZAWA   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Toll-like receptor signaling in cell proliferation and survival

(2009) Xinyan Li et al.   CYTOKINE

Differential Effect of Saturated and Unsaturated Free Fatty Acids on the Generation of Monocyte Adhesion and Chemotactic Factors by Adipocytes: Dissociation of Adipocyte Hypertrophy From Inflammation

(2009) C. Y. Han et al.   DIABETES

Regulatory Mechanisms for Adipose Tissue M1 and M2 Macrophages in Diet-Induced Obese Mice

(2009) S. Fujisaka et al.   DIABETES

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

(2009) Satoshi Nishimura et al.   NATURE MEDICINE

LPS/TLR4 signal transduction pathway

(2008) Yong-Chen Lu et al.   CYTOKINE

Orally administered eicosapentaenoic acid reduces and stabilizes atherosclerotic lesions in ApoE-deficient mice

(2007) Miwa Matsumoto et al.   ATHEROSCLEROSIS