G-quadruplex structure of an anti-proliferative DNA sequence

The G-quadruplex-forming aptamer AS1411 potently inhibits HIV-1 attachment to the host cell

(2016) Rosalba Perrone et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Anticancer molecule AS1411 exhibits low nanomolar antiviral activity against HIV-1

(2015) Mathieu Métifiot et al.   BIOCHIMIE

Targeting VEGF with LNA-stabilized G-rich oligonucleotide for efficient breast cancer inhibition

(2015) Stacey L. Edwards et al.   CHEMICAL COMMUNICATIONS

G-Quadruplex Forming Oligonucleotides as Anti-HIV Agents

(2015) Domenica Musumeci et al.   MOLECULES

G-quadruplexes with (4n - 1) guanines in the G-tetrad core: formation of a G-triad·water complex and implication for small-molecule binding

(2015) Brahim Heddi et al.   NUCLEIC ACIDS RESEARCH

Structure of a left-handed DNA G-quadruplex

(2015) Wan Jun Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytotoxicity of guanine-based degradation products contributes to the antiproliferative activity of guanine-rich oligonucleotides

(2015) Nan Zhang et al.   Chemical Science

Structural Basis of DNA Quadruplex-Duplex Junction Formation

(2013) Kah Wai Lim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A phase II trial of AS1411 (a novel nucleolin-targeted DNA aptamer) in metastatic renal cell carcinoma

(2013) Jonathan E. Rosenberg et al.   INVESTIGATIONAL NEW DRUGS

Bulges in G-Quadruplexes: Broadening the Definition of G-Quadruplex-Forming Sequences

(2013) Vineeth Thachappilly Mukundan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity

(2012) Irene Russo Krauss et al.   NUCLEIC ACIDS RESEARCH

Stacking of G-quadruplexes: NMR structure of a G-rich oligonucleotide with potential anti-HIV and anticancer activity†

(2011) Ngoc Quang Do et al.   NUCLEIC ACIDS RESEARCH

HIV-1 integrase inhibitor T30177 forms a stacked dimeric G-quadruplex structure containing bulges

(2011) Vineeth Thachappilly Mukundan et al.   NUCLEIC ACIDS RESEARCH

Tetramolecular DNA Quadruplexes in Solution: Insights into Structural Diversity and Cation Movement

(2010) Primož Šket et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Resolution and characterization of the structural polymorphism of a single quadruplex-forming sequence

(2010) Magdalena M. Dailey et al.   NUCLEIC ACIDS RESEARCH

Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer

(2009) Paula J. Bates et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Human telomeric G-quadruplex: structures of DNA and RNA sequences

(2009) Anh Tuân Phan   FEBS Journal

Structure of Propeller-Type Parallel-Stranded RNA G-Quadruplexes, Formed by Human Telomeric RNA Sequences in K+Solution

(2009) Herry Martadinata et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cancer-selective antiproliferative activity is a general property of some G-rich oligodeoxynucleotides

(2009) Enid W. Choi et al.   NUCLEIC ACIDS RESEARCH

G-Quadruplex DNA Assemblies: Loop Length, Cation Identity, and Multimer Formation†

(2008) Nicolas Smargiasso et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY