Avoidance of APOBEC3B-induced mutation by error-free lesion bypass

Interaction between the Rev1 C-Terminal Domain and the PolD3 Subunit of Polζ Suggests a Mechanism of Polymerase Exchange upon Rev1/Polζ-Dependent Translesion Synthesis

(2016) Yulia Pustovalova et al.   BIOCHEMISTRY

Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair

(2016) Nicholas J. Haradhvala et al.   CELL

APOBEC3A damages the cellular genome during DNA replication

(2016) Abby M. Green et al.   CELL CYCLE

Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance

(2016) Sonia Silva et al.   GENES & DEVELOPMENT

Differential regulation of the anti-crossover and replication fork regression activities of Mph1 by Mte1

(2016) Xiaoyu Xue et al.   GENES & DEVELOPMENT

MTE1 Functions with MPH1 in Double-Strand Break Repair

(2016) Askar Yimit et al.   GENETICS

APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication

(2016) Vladimir B. Seplyarskiy et al.   GENOME RESEARCH

A defect in homologous recombination leads to increased translesion synthesisin E. coli

(2016) Karel Naiman et al.   NUCLEIC ACIDS RESEARCH

Involvement of budding yeast Rad5 in translesion DNA synthesis through physical interaction with Rev1

(2016) Xin Xu et al.   NUCLEIC ACIDS RESEARCH

Strand-biased cytosine deamination at the replication fork causes cytosine to thymine mutations inEscherichia coli

(2016) Ashok S. Bhagwat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The topography of mutational processes in breast cancer genomes

(2016) Sandro Morganella et al.   Nature Communications

APOBEC3A and APOBEC3B Preferentially Deaminate the Lagging Strand Template during DNA Replication

(2016) James I. Hoopes et al.   Cell Reports

MTE1 Functions with MPH1 in Double-Strand Break Repair

(2016) Askar Yimit et al.   GENETICS

Error-free DNA-damage tolerance in Saccharomyces cerevisiae

(2015) Xin Xu et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

SMRT Sequencing for Parallel Analysis of Multiple Targets and Accurate SNP Phasing

(2015) Xiaoge Guo et al.   G3-Genes Genomes Genetics

Disruption of Transcriptional Coactivator Sub1 Leads to Genome-Wide Re-distribution of Clustered Mutations Induced by APOBEC in Active Yeast Genes

(2015) Artem G. Lada et al.   PLoS Genetics

Mutational Context and Diverse Clonal Development in Early and Late Bladder Cancer

(2014) Iver Nordentoft et al.   Cell Reports

The choice of nucleotide inserted opposite abasic sites formed within chromosomal DNA reveals the polymerase activities participating in translesion DNA synthesis

(2013) Kin Chan et al.   DNA REPAIR

DNA Repair Mechanisms and the Bypass of DNA Damage in Saccharomyces cerevisiae

(2013) S. Boiteux et al.   GENETICS

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Evidence for APOBEC3B mutagenesis in multiple human cancers

(2013) Michael B Burns et al.   NATURE GENETICS

An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers

(2013) Steven A Roberts et al.   NATURE GENETICS

Prereplicative repair of oxidized bases in the human genome is mediated by NEIL1 DNA glycosylase together with replication proteins

(2013) M. L. Hegde et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutational Processes Molding the Genomes of 21 Breast Cancers

(2012) Serena Nik-Zainal et al.   CELL

APOBEC3 proteins and genomic stability

(2012) Iñigo Narvaiza et al.   CELL CYCLE

Clustered Mutations in Yeast and in Human Cancers Can Arise from Damaged Long Single-Strand DNA Regions

(2012) Steven A. Roberts et al.   MOLECULAR CELL

The Mph1 Helicase Can Promote Telomere Uncapping and Premature Senescence in Budding Yeast

(2012) Sarah Luke-Glaser et al.   PLoS One

APOBEC3A can activate the DNA damage response and cause cell-cycle arrest

(2011) Sébastien Landry et al.   EMBO REPORTS

The Non-canonical Protein Binding Site at the Monomer-Monomer Interface of Yeast Proliferating Cell Nuclear Antigen (PCNA) Regulates the Rev1-PCNA Interaction and Polζ/Rev1-dependent Translesion DNA Synthesis

(2011) Neeru M. Sharma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Maintaining genome stability at the replication fork

(2010) Dana Branzei et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination

(2009) R. Prakash et al.   GENES & DEVELOPMENT

The Block of DNA Polymerase δ Strand Displacement Activity by an Abasic Site Can Be Rescued by the Concerted Action of DNA Polymerase β and Flap Endonuclease 1

(2009) Giovanni Maga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TheMPH1Gene ofSaccharomyces cerevisiaeFunctions in Okazaki Fragment Processing

(2009) Young-Hoon Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY