Disruption of Transcriptional Coactivator Sub1 Leads to Genome-Wide Re-distribution of Clustered Mutations Induced by APOBEC in Active Yeast Genes

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Clustered and genome-wide transient mutagenesis in human cancers: Hypermutation without permanent mutators or loss of fitness

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B Cell Super-Enhancers and Regulatory Clusters Recruit AID Tumorigenic Activity

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Epigenetic targeting of activation-induced cytidine deaminase

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AID and APOBEC deaminases: balancing DNA damage in epigenetics and immunity

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Break-Induced Replication Is a Source of Mutation Clusters Underlying Kataegis

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Active RNAP pre-initiation sites are highly mutated by cytidine deaminases in yeast, with AID targeting small RNA genes

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DNA Sequences That Interfere with Transcription: Implications for Genome Function and Stability

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APOBEC3B is an enzymatic source of mutation in breast cancer

(2013) Michael B. Burns et al.   NATURE

Mutational heterogeneity in cancer and the search for new cancer-associated genes

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Evidence for APOBEC3B mutagenesis in multiple human cancers

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An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers

(2013) Steven A Roberts et al.   NATURE GENETICS

DNA polymerases ζ and Rev1 mediate error-prone bypass of non-B DNA structures

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Genome-Wide Mutation Avalanches Induced in Diploid Yeast Cells by a Base Analog or an APOBEC Deaminase

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DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis

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AID/APOBEC cytosine deaminase induces genome-wide kataegis

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Mutational Processes Molding the Genomes of 21 Breast Cancers

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Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide pools

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A role for the RNA pol II–associated PAF complex in AID-induced immune diversification

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Clustered Mutations in Yeast and in Human Cancers Can Arise from Damaged Long Single-Strand DNA Regions

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R Loops: From Transcription Byproducts to Threats to Genome Stability

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APOBEC3B can impair genomic stability by inducing base substitutions in genomic DNA in human cells

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Mutator effects and mutation signatures of editing deaminases produced in bacteria and yeast

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The multiple personalities of Watson and Crick strands

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Guanine repeat-containing sequences confer transcription-dependent instability in an orientation-specific manner in yeast

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Sub1 and RPA Associate with RNA Polymerase II at Different Stages of Transcription

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Replication Protein A (RPA) Hampers the Processive Action of APOBEC3G Cytosine Deaminase on Single-Stranded DNA

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Replication protein A: directing traffic at the intersection of replication and repair

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Sub1/PC4 a chromatin associated protein with multiple functions in transcription

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Mutator phenotypes due to DNA replication infidelity

(2010) Mercedes E. Arana et al.   SEMINARS IN CANCER BIOLOGY

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Participation of DNA Polymerase   in Replication of Undamaged DNA in Saccharomyces cerevisiae

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RNA polymerase II–TFIIB structure and mechanism of transcription initiation

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The evolutionary consequences of erroneous protein synthesis

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Nano positioning system reveals the course of upstream and nontemplate DNA within the RNA polymerase II elongation complex

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Structure of an RNA Polymerase II-TFIIB Complex and the Transcription Initiation Mechanism

(2009) X. Liu et al.   SCIENCE

Transcriptional pausing and stalling causes multiple clustered mutations by human activation-induced deaminase

(2008) Chandrika Canugovi et al.   FASEB JOURNAL

Transcription induces strand-specific mutations at the 5' end of human genes

(2008) P. Polak et al.   GENOME RESEARCH

Impact of Phosphorylation and Phosphorylation-null Mutants on the Activity and Deamination Specificity of Activation-induced Cytidine Deaminase

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Transcription-coupled DNA repair: two decades of progress and surprises

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Stochastic properties of processive cytidine DNA deaminases AID and APOBEC3G

(2008) L. Chelico et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The Transcriptional Landscape of the Yeast Genome Defined by RNA Sequencing

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