NRF2 regulates endothelial glycolysis and proliferation with miR-93 and mediates the effects of oxidized phospholipids on endothelial activation

Human Pericardial Fluid Contains Exosomes Enriched with Cardiovascular-Expressed MicroRNAs and Promotes Therapeutic Angiogenesis

(2017) Cristina Beltrami et al.   MOLECULAR THERAPY

Vascular heterogeneity and specialization in development and disease

(2017) Michael Potente et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Endothelial miRNAs as Cellular Messengers in Cardiometabolic Diseases

(2017) Makon-Sébastien Njock et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Angiogenesis in the atherosclerotic plaque

(2017) Caroline Camaré et al.   Redox Biology

MicroRNA Profiling Reveals Distinct Profiles for Tissue-Derived and Cultured Endothelial Cells

(2017) Suvi M. Kuosmanen et al.   Scientific Reports

Precise mapping of the transcription start sites of human microRNAs using DROSHA knockout cells

(2016) Geon Jeong et al.   BMC GENOMICS

MicroRNA Regulation of Atherosclerosis

(2016) Mark W. Feinberg et al.   CIRCULATION RESEARCH

Transcriptional control of endothelial energy

(2016) Christer Betsholtz   NATURE

FOXO1 couples metabolic activity and growth state in the vascular endothelium

(2016) Kerstin Wilhelm et al.   NATURE

The Effects of Sequence Variation on Genome-wide NRF2 Binding—New Target Genes and Regulatory SNPs

(2016) Suvi M. Kuosmanen et al.   NUCLEIC ACIDS RESEARCH

Extracellular vesicle microRNA transfer in cardiovascular disease

(2015) Samarjit Das et al.   CARDIOVASCULAR PATHOLOGY

MicroRNA-mediated mechanisms of the cellular stress response in atherosclerosis

(2015) Andreas Schober et al.   Nature Reviews Cardiology

miRNAs in atherosclerotic plaque initiation, progression, and rupture

(2015) Ioannis Andreou et al.   TRENDS IN MOLECULAR MEDICINE

MicroRNA Profiling of Pericardial Fluid Samples from Patients with Heart Failure

(2015) Suvi M. Kuosmanen et al.   PLoS One

MicroRNA miR-320a modulates induction of HO-1, GCLM and OKL38 by oxidized phospholipids in endothelial cells

(2014) Waltraud C. Schrottmaier et al.   ATHEROSCLEROSIS

NRF2-driven miR-125B1 and miR-29B1 transcriptional regulation controls a novel anti-apoptotic miRNA regulatory network for AML survival

(2014) N M Shah et al.   CELL DEATH AND DIFFERENTIATION

Metabolism of stromal and immune cells in health and disease

(2014) Bart Ghesquière et al.   NATURE

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization

(2014) Minna U. Kaikkonen et al.   NUCLEIC ACIDS RESEARCH

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

(2014) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Division of labour between Myc and G1 cyclins in cell cycle commitment and pace control

(2014) Peng Dong et al.   Nature Communications

MicroRNA-93 regulates NRF2 expression and is associated with breast carcinogenesis

(2013) B. Singh et al.   CARCINOGENESIS

Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

(2013) Katrien De Bock et al.   CELL

Partial and Transient Reduction of Glycolysis by PFKFB3 Blockade Reduces Pathological Angiogenesis

(2013) Sandra Schoors et al.   Cell Metabolism

miRBase: annotating high confidence microRNAs using deep sequencing data

(2013) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

Signature of Circulating MicroRNAs as Potential Biomarkers in Vulnerable Coronary Artery Disease

(2013) Jingyi Ren et al.   PLoS One

Nrf2 acts cell-autonomously in endothelium to regulate tip cell formation and vascular branching

(2013) Y. Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer

(2013) Emilia Kansanen et al.   Redox Biology

Permissive role of miR-663 in induction of VEGF and activation of the ATF4 branch of unfolded protein response in endothelial cells by oxidized phospholipids

(2012) Taras Afonyushkin et al.   ATHEROSCLEROSIS

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

(2012) H. Thorvaldsdottir et al.   BRIEFINGS IN BIOINFORMATICS

MiR-93 enhances angiogenesis and metastasis by targeting LATS2

(2012) Ling Fang et al.   CELL CYCLE

Role of Phospholipid Oxidation Products in Atherosclerosis

(2012) Sangderk Lee et al.   CIRCULATION RESEARCH

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation

(2012) Davis J. McCarthy et al.   NUCLEIC ACIDS RESEARCH

TSA Suppresses miR-106b-93-25 Cluster Expression through Downregulation of MYC and Inhibits Proliferation and Induces Apoptosis in Human EMC

(2012) Zhi-Ning Zhao et al.   PLoS One

miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere Vascular Study

(2011) Emma Raitoharju et al.   ATHEROSCLEROSIS

Pervasive roles of microRNAs in cardiovascular biology

(2011) Eric M. Small et al.   NATURE

Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA

(2011) Dong Wang et al.   NATURE

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

(2011) Jeng-Jiann Chiu et al.   PHYSIOLOGICAL REVIEWS

Oxidized Phospholipids Regulate Expression of ATF4 and VEGF in Endothelial Cells via NRF2-Dependent Mechanism: Novel Point of Convergence Between Electrophilic and Unfolded Protein Stress Pathways

(2010) Taras Afonyushkin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Circulating CD31+/Annexin V+ microparticles correlate with cardiovascular outcomes

(2010) J.-M. Sinning et al.   EUROPEAN HEART JOURNAL

MicroRNA miR-93 promotes tumor growth and angiogenesis by targeting integrin-β8

(2010) L Fang et al.   ONCOGENE

Generation and Biological Activities of Oxidized Phospholipids

(2009) Valery N. Bochkov et al.   ANTIOXIDANTS & REDOX SIGNALING

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Nrf2 Regulates Antioxidant Gene Expression Evoked by Oxidized Phospholipids in Endothelial Cells and Murine Arteries In Vivo

(2008) Henna-Kaisa Jyrkkänen et al.   CIRCULATION RESEARCH