An efficient approach to 3-oxoisoindoline-1-difluoroalkyl derivatives via a metal triflate-catalyzed Mannich/lactamization cascade reaction

Chiral Phosphoric Acid Catalyzed Asymmetric Ugi Reaction by Dynamic Kinetic Resolution of the Primary Multicomponent Adduct

(2016) Yun Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sc(OTf)3-catalyzed three-component cascade reaction: One-pot synthesis of substituted 3-oxoisoindoline-1-carbonitrile derivatives

(2016) Tingting Chen et al.   CATALYSIS COMMUNICATIONS

Visible-light-initiated difluoromethylation of arene diazonium tetrafluoroborates

(2016) Ye-bin Wu et al.   CHEMICAL COMMUNICATIONS

Silica-supported metal acetylacetonate catalysts with a robust and flexible linker constructed by using 2-butoxy-3,4-dihydropyrans as dual anchoring reagents and ligand donors

(2016) Bingbing Lai et al.   Catalysis Science & Technology

Organocatalytic enantioselective Mukaiyama–Mannich reaction of fluorinated enol silyl ethers and cyclic N-sulfonyl ketimines

(2016) Jin-Sheng Yu et al.   Organic Chemistry Frontiers

Advances in Transition-Metal-Mediated Di-and Monofluoroalkylations

(2015) Chuanfa Ni et al.   ACTA CHIMICA SINICA

Monofluorination of Organic Compounds: 10 Years of Innovation

(2015) Pier Alexandre Champagne et al.   CHEMICAL REVIEWS

Efficient syntheses of substituted (±)-3-oxoisoindoline-1-carbonitriles and carboxamides using OSU-6

(2015) Baskar Nammalwar et al.   GREEN CHEMISTRY

Fluorinated enol ethers: their synthesis and reactivity

(2015) M. Decostanzi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A highly efficient Mukaiyama–Mannich reaction of N-Boc isatin ketimines and other active cyclic ketimines using difluoroenol silyl ethers catalyzed by Ph3PAuOTf

(2015) Jin-Sheng Yu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Ni(II)-Catalyzed Highly Stereo- and Regioselective Syntheses of Isoindolinones and Isoquinolinones from in Situ Prepared Aldimines Triggered by Homoallylation/Lactamization Cascade

(2015) Raju Karmakar et al.   ORGANIC LETTERS

An Efficient Entry to syn- and anti-Selective Isoindolinones via an Organocatalytic Direct Mannich/Lactamization Sequence

(2015) Vishnumaya Bisai et al.   ORGANIC LETTERS

Unified Approach to Isoindolinones and THIQs via Lewis Acid Catalyzed Domino Mukaiyama–Mannich Lactamization/Alkylations: Application in the Synthesis of (±)-Homolaudanosine

(2015) Sivasankaran Dhanasekaran et al.   ORGANIC LETTERS

Highly Efficient “On Water” Catalyst-Free Nucleophilic Addition Reactions Using Difluoroenoxysilanes: Dramatic Fluorine Effects

(2014) Jin-Sheng Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Alkynylation/Lactamization Cascade: An Expeditious Entry to Enantiomerically Enriched Isoindolinones

(2014) Vishnumaya Bisai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Advances in Catalytic Enantioselective Fluorination, Mono-, Di-, and Trifluoromethylation, and Trifluoromethylthiolation Reactions

(2014) Xiaoyu Yang et al.   CHEMICAL REVIEWS

Synthesis of 2-substituted-3-(1H-indol-3-yl)isoindolin-1-one derivatives in water under catalyst-free conditions

(2014) Fanglei Chen et al.   GREEN CHEMISTRY

A General Catalytic Route to Isoindolinones and Tetrahydroisoquinolines: Application in the Synthesis of (±)-Crispine A

(2014) Sivasankaran Dhanasekaran et al.   ORGANIC LETTERS

Catalytic fluorination of unactivated C(sp3)–H bonds

(2014) Jun-An Ma et al.   Organic Chemistry Frontiers

Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

(2013) Jiang Wang et al.   CHEMICAL REVIEWS

Highly Enantioselective Organocatalytic Asymmetric Mukaiyama-aldol Reaction of Difluoroenoxysilanes withβ,γ-Unsaturatedα-Ketoesters

(2012) Yunlin Liu et al.   ACTA CHIMICA SINICA

Progress in fluoroalkylation of organic compounds via sulfinatodehalogenation initiation system

(2012) Cheng-Pan Zhang et al.   CHEMICAL SOCIETY REVIEWS

Indium-Promoted Reformatsky Reaction: A Straightforward Access to β-Amino and β-Hydroxy α,α-Difluoro Carbonyl Compounds

(2012) Thomas Poisson et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric catalytic Mannich-type reaction of hydrazones with difluoroenoxysilanes using imidazoline-anchored phosphine ligand–zinc(ii) complexes

(2012) Zhiliang Yuan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Development of a copper(II)-catalyzed three-component tandem synthesis of isoindolinone derivatives

(2011) Leon Xuetong Sun et al.   CANADIAN JOURNAL OF CHEMISTRY

Organocatalytic asymmetric synthesis of 3-difluoroalkyl 3-hydroxyoxindoles

(2011) Yun-Lin Liu et al.   CHEMICAL COMMUNICATIONS

Chiral Phosphoric Acid Catalyzed Enantioselective Synthesis of β-Amino-α,α-difluoro Carbonyl Compounds

(2011) Wataru Kashikura et al.   ORGANIC LETTERS

One-Pot Synthesis of Isoindolinones via Three-Component Mannich/Lactamization Cascade Reaction

(2011) Haoyi Zhang et al.   SYNTHETIC COMMUNICATIONS

Zinc(II)-Catalyzed Mannich-type Reactions of Hydrazones with Difluoroenoxysilane and Its Application in the Synthesis of Optically Active 2,2-Difluoro-3-oxo-benzohydrazide

(2010) Zhiliang Yuan et al.   CHINESE JOURNAL OF CHEMISTRY

Reaction of aldimines and difluoroenoxysilane, an unexpected protocol for the synthesis of 2,2-difluoro-3-hydroxy-1-ones

(2010) Zhi-Liang Yuan et al.   TETRAHEDRON

7-[1H-Indol-2-yl]-2,3-dihydro-isoindol-1-ones as dual Aurora-A/VEGF-R2 kinase inhibitors: Design, synthesis, and biological activity

(2008) Terry V. Hughes et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Understanding organofluorine chemistry. An introduction to the C–F bond

(2007) David O'Hagan   CHEMICAL SOCIETY REVIEWS