BMAA and Neurodegenerative Illness

Detection of Cyanotoxins in Algae Dietary Supplements

(2017) Audrey Roy-Lachapelle et al.   Toxins

New Typical Vector of Neurotoxin β-N-Methylamino-l-Alanine (BMAA) in the Marine Benthic Ecosystem

(2016) Aifeng Li et al.   Marine Drugs

Do vervets and macaques respond differently to BMAA?

(2016) Paul Alan Cox et al.   NEUROTOXICOLOGY

Dietary exposure to an environmental toxin triggers neurofibrillary tangles and amyloid deposits in the brain

(2016) Paul Alan Cox et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Transfer of developmental neurotoxin β- N -methylamino- l -alanine (BMAA) via milk to nursed offspring: Studies by mass spectrometry and image analysis

(2016) Marie Andersson et al.   TOXICOLOGY LETTERS

Phase I clinical trial of safety of L-serine for ALS patients

(2016) Todd D. Levine et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Equilibrium Dynamics of β-N-Methylamino-L-Alanine (BMAA) and Its Carbamate Adducts at Physiological Conditions

(2016) David Zimmerman et al.   PLoS One

Improved detection of β-N-methylamino-l-alanine using N-hydroxysuccinimide ester of N-butylnicotinic acid for the localization of BMAA in blue mussels (Mytilus edulis)

(2015) Rudolf Andrýs et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Selective quantitation of the neurotoxin BMAA by use of hydrophilic-interaction liquid chromatography–differential mobility spectrometry–tandem mass spectrometry (HILIC–DMS–MS/MS)

(2015) Daniel G. Beach et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Geographical modeling of exposure risk to cyanobacteria for epidemiological purposes

(2015) Tania Serrano et al.   ENVIRONMENT INTERNATIONAL

Assessment of the non-protein amino acid BMAA in Mediterranean mussel Mytilus galloprovincialis after feeding with estuarine cyanobacteria

(2015) Mafalda S. Baptista et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Determination of β-N-methylamino-L-alanine, N-(2-aminoethyl)glycine, and 2,4-diaminobutyric acid in Food Products Containing Cyanobacteria by Ultra-Performance Liquid Chromatography and Tandem Mass Spectrometry: Single-Laboratory Validation

(2015) W. Broc Glover et al.   JOURNAL OF AOAC INTERNATIONAL

The persistence of cyanobacterial toxins in desert soils

(2015) Renee Richer et al.   JOURNAL OF ARID ENVIRONMENTS

Neurotoxic amino acids and their isomers in desert environments

(2015) J.S. Metcalf et al.   JOURNAL OF ARID ENVIRONMENTS

β-N-methylamino-l-alanine (BMAA) and isomers: Distribution in different food web compartments of Thau lagoon, French Mediterranean Sea

(2015) Damien Réveillon et al.   MARINE ENVIRONMENTAL RESEARCH

A Multiscale Mapping Assessment of Lake Champlain Cyanobacterial Harmful Algal Blooms

(2015) Nathan Torbick et al.   International Journal of Environmental Research and Public Health

BMAA in shellfish from two Portuguese transitional water bodies suggests the marine dinoflagellate Gymnodinium catenatum as a potential BMAA source

(2014) Sandra Lage et al.   AQUATIC TOXICOLOGY

The fate of the cyanobacterial toxin β-N-methylamino-l-alanine in freshwater mussels

(2014) Simoné Downing et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Environmental neurotoxins β-N-methylamino-l-alanine (BMAA) and mercury in shark cartilage dietary supplements

(2014) Kiyo Mondo et al.   FOOD AND CHEMICAL TOXICOLOGY

Beta-N-Methylamino-l-Alanine: LC-MS/MS Optimization, Screening of Cyanobacterial Strains and Occurrence in Shellfish from Thau, a French Mediterranean Lagoon

(2014) Damien Réveillon et al.   Marine Drugs

Tau pathology involves protein phosphatase 2A in Parkinsonism-dementia of Guam

(2014) M. Arif et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of cyanobacterial neurotoxin β-N-methylamino-l-alanine within shellfish in the diet of an ALS patient in Florida

(2014) Sandra Anne Banack et al.   TOXICON

Quantification of neurotoxin BMAA (β-N-methylamino-L-alanine) in seafood from Swedish markets

(2014) Liying Jiang et al.   Scientific Reports

Mapping amyotrophic lateral sclerosis lake risk factors across northern New England

(2014) Nathan Torbick et al.   International Journal of Health Geographics

Development and in-house validation of a method for quantification of BMAA in mussels using dansyl chloride derivatization and ultra performance liquid chromatography tandem mass spectrometry

(2013) Matilda Lampinen Salomonsson et al.   Analytical Methods

β-N-methylamino-l-alanine causes neurological and pathological phenotypes mimicking Amyotrophic Lateral Sclerosis (ALS): The first step towards an experimental model for sporadic ALS

(2013) Estefanía de Munck et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

The Non-Protein Amino Acid BMAA Is Misincorporated into Human Proteins in Place of l-Serine Causing Protein Misfolding and Aggregation

(2013) Rachael Anne Dunlop et al.   PLoS One

Dietary BMAA Exposure in an Amyotrophic Lateral Sclerosis Cluster from Southern France

(2013) Estelle Masseret et al.   PLoS One

Linking β-methylamino-l-alanine exposure to sporadic amyotrophic lateral sclerosis in Annapolis, MD

(2013) Nicholas C. Field et al.   TOXICON

Is exposure to cyanobacteria an environmental risk factor for amyotrophic lateral sclerosis and other neurodegenerative diseases?

(2013) Walter G. Bradley et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

BMAALS: A French national project searching for a link between amyotrophic lateral sclerosis and the neurotoxic amino acid L-BMAA

(2013) Aurelie Delzor et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Aerosolization of cyanobacteria as a risk factor for amyotrophic lateral sclerosis

(2012) Elijah W. Stommel et al.   MEDICAL HYPOTHESES

Cyanotoxins in desert environments may present a risk to human health

(2012) J.S. Metcalf et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Synergistic toxicity of the environmental neurotoxins methylmercury and β-N-methylamino-L-alanine

(2011) Travis Rush et al.   NEUROREPORT

Nitrogen starvation of cyanobacteria results in the production of β-N-methylamino-L-alanine

(2011) S. Downing et al.   TOXICON

Cyanobacterial blooms and the occurrence of the neurotoxin, beta-N-methylamino-l-alanine (BMAA), in South Florida aquatic food webs

(2010) Larry E. Brand et al.   HARMFUL ALGAE

Transfer of a cyanobacterial neurotoxin within a temperate aquatic ecosystem suggests pathways for human exposure

(2010) S. Jonasson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The discovery of BMAA, and examples of biomagnification and protein incorporation involving other non-protein amino acids

(2009) E. Arthur Bell   Amyotrophic Lateral Sclerosis

Cyanobacteria and BMAA exposure from desert dust: A possible link to sporadic ALS among Gulf War veterans

(2009) Paul Alan Cox et al.   Amyotrophic Lateral Sclerosis

Previous studies underestimate BMAA concentrations in cycad flour

(2009) Ran Cheng et al.   Amyotrophic Lateral Sclerosis

Three phases of research on β-N-methylamino-L-alanine (BMAA) - a neurotoxic amino acid

(2009) Peter B. Nunn   Amyotrophic Lateral Sclerosis

A cluster of amyotrophic lateral sclerosis in New Hampshire: A possible role for toxic cyanobacteria blooms

(2009) Tracie A. Caller et al.   Amyotrophic Lateral Sclerosis

Beyond Guam: The cyanobacteria/BMAA hypothesis of the cause of ALS and other neurodegenerative diseases

(2009) Walter G. Bradley et al.   Amyotrophic Lateral Sclerosis

Co-occurrence of β-N-methylamino-l-alanine, a neurotoxic amino acid with other cyanobacterial toxins in British waterbodies, 1990–2004

(2008) James S. Metcalf et al.   ENVIRONMENTAL MICROBIOLOGY

Animal models of BMAA neurotoxicity: A critical review

(2008) Vardan T. Karamyan et al.   LIFE SCIENCES