The BigLEN-GPR171 Peptide Receptor System Within the Basolateral Amygdala Regulates Anxiety-Like Behavior and Contextual Fear Conditioning

CRF receptor type 1 (but not type 2) located within the amygdala plays a role in the modulation of anxiety in mice exposed to the elevated plus maze

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Neuropeptide Y input to the rat basolateral amygdala complex and modulation by conditioned fear

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Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake

(2016) Jonathan H. Wardman et al.   Science Signaling

Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake

(2016) Jonathan H. Wardman et al.   Science Signaling

Insights into the interaction of negative allosteric modulators with the metabotropic glutamate receptor 5: Discovery and computational modeling of a new series of ligands with nanomolar affinity

(2015) Andrew Anighoro et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Increased Basolateral Amygdala Pyramidal Cell Excitability May Contribute to the Anxiogenic Phenotype Induced by Chronic Early-Life Stress

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Sex Differences in Nucleus Accumbens Transcriptome Profiles Associated with Susceptibility versus Resilience to Subchronic Variable Stress

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Brain and other nervous system disorders across the lifespan — global challenges and opportunities

(2015) Donald Silberberg et al.   NATURE

Advancements in therapeutically targeting orphan GPCRs

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Leucine-Rich Repeat Kinase 2 Binds to Neuronal Vesicles through Protein Interactions Mediated by Its C-Terminal WD40 Domain

(2014) G. Piccoli et al.   MOLECULAR AND CELLULAR BIOLOGY

Sequence-structure based phylogeny of GPCR Class A Rhodopsin receptors

(2014) Kavita Kumari Kakarala et al.   MOLECULAR PHYLOGENETICS AND EVOLUTION

Anxiolytic-like effects after vector-mediated overexpression of neuropeptide Y in the amygdala and hippocampus of mice

(2014) S.H. Christiansen et al.   NEUROPEPTIDES

Distinct Effects of Repeated Restraint Stress on Basolateral Amygdala Neuronal Membrane Properties in Resilient Adolescent and Adult Rats

(2014) Andrea Hetzel et al.   NEUROPSYCHOPHARMACOLOGY

NPY mediates reward activity of morphine, via NPY Y1 receptors, in the nucleus accumbens shell

(2013) Sagar J. Desai et al.   BEHAVIOURAL BRAIN RESEARCH

The contextual brain: implications for fear conditioning, extinction and psychopathology

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BLA to vHPC Inputs Modulate Anxiety-Related Behaviors

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Amygdala and bed nucleus of the stria terminalis circuitry: Implications for addiction-related behaviors

(2013) Alice M. Stamatakis et al.   NEUROPHARMACOLOGY

GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding

(2013) I. Gomes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AT1R-CB1R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II

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Rapid, reversible activation of AgRP neurons drives feeding behavior in mice

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ProSAAS-Derived Peptides are Colocalized with Neuropeptide Y and Function as Neuropeptides in the Regulation of Food Intake

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The Central and Basolateral Amygdala Are Critical Sites of Neuropeptide Y/Y2 Receptor-Mediated Regulation of Anxiety and Depression

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Analysis of mouse brain peptides using mass spectrometry-based peptidomics: implications for novel functions ranging from non-classical neuropeptides to microproteins

(2010) Lloyd D. Fricker   Molecular BioSystems

Lateral Paracapsular GABAergic Synapses in the Basolateral Amygdala Contribute to the Anxiolytic Effects of β3 Adrenoceptor Activation

(2010) Yuval Silberman et al.   NEUROPSYCHOPHARMACOLOGY

Increased Abundance of Opioid Receptor Heteromers After Chronic Morphine Administration

(2010) A. Gupta et al.   Science Signaling

Novel endogenous peptide agonists of cannabinoid receptors

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Discovery of Novel Chemotypes to a G-Protein-Coupled Receptor through Ligand-Steered Homology Modeling and Structure-Based Virtual Screening

(2008) Claudio N. Cavasotto et al.   JOURNAL OF MEDICINAL CHEMISTRY

Peptidomics ofCpefat/fatmouse brain regions: implications for neuropeptide processing

(2008) Xin Zhang et al.   JOURNAL OF NEUROCHEMISTRY

Neuropeptide Y in the Amygdala Induces Long-Term Resilience to Stress-Induced Reductions in Social Responses But Not Hypothalamic-Adrenal-Pituitary Axis Activity or Hyperthermia

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