Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake
Authors
Keywords
-
Journal
Science Signaling
Volume 9, Issue 430, Pages ra55-ra55
Publisher
American Association for the Advancement of Science (AAAS)
Online
2016-06-01
DOI
10.1126/scisignal.aac8035
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Identification of GPR83 as the receptor for the neuroendocrine peptide PEN
- (2016) Ivone Gomes et al. Science Signaling
- Identification of GPR83 as the receptor for the neuroendocrine peptide PEN
- (2016) Ivone Gomes et al. Science Signaling
- Network of hypothalamic neurons that control appetite
- (2015) Jong-Woo Sohn BMB Reports
- Discovery of GPCR Ligands by Molecular Docking Screening: Novel Opportunities Provided by Crystal Structures
- (2015) David Rodríguez et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Two disparate ligand-binding sites in the human P2Y1 receptor
- (2015) Dandan Zhang et al. NATURE
- Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65
- (2015) Xi-Ping Huang et al. NATURE
- Sequence-structure based phylogeny of GPCR Class A Rhodopsin receptors
- (2014) Kavita Kumari Kakarala et al. MOLECULAR PHYLOGENETICS AND EVOLUTION
- Agonist-bound structure of the human P2Y12 receptor
- (2014) Jin Zhang et al. NATURE
- Structure of the human P2Y12 receptor in complex with an antithrombotic drug
- (2014) Kaihua Zhang et al. NATURE
- Optogenetic and chemogenetic insights into the food addiction hypothesis
- (2014) Michael J. Krashes et al. Frontiers in Behavioral Neuroscience
- Parallel, Redundant Circuit Organization for Homeostatic Control of Feeding Behavior
- (2013) J. Nicholas Betley et al. CELL
- Rapid versus Delayed Stimulation of Feeding by the Endogenously Released AgRP Neuron Mediators GABA, NPY, and AgRP
- (2013) Michael J. Krashes et al. Cell Metabolism
- Activities at the Universal Protein Resource (UniProt)
- (2013) NUCLEIC ACIDS RESEARCH
- GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding
- (2013) I. Gomes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Anti-obesity drugs: past, present and future
- (2012) R. J. Rodgers et al. Disease Models & Mechanisms
- Gpr171, a putative P2Y-like receptor, negatively regulates myeloid differentiation in murine hematopoietic progenitors
- (2012) Lara Rossi et al. EXPERIMENTAL HEMATOLOGY
- AT1R-CB1R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II
- (2011) Raphael Rozenfeld et al. EMBO JOURNAL
- Rapid, reversible activation of AgRP neurons drives feeding behavior in mice
- (2011) Michael J. Krashes et al. JOURNAL OF CLINICAL INVESTIGATION
- Ligand discovery from a dopamine D3 receptor homology model and crystal structure
- (2011) Jens Carlsson et al. Nature Chemical Biology
- AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training
- (2011) Yexica Aponte et al. NATURE NEUROSCIENCE
- ProSAAS-Derived Peptides are Colocalized with Neuropeptide Y and Function as Neuropeptides in the Regulation of Food Intake
- (2011) Jonathan H. Wardman et al. PLoS One
- Therapeutic potential of neuropeptide Y (NPY) receptor ligands
- (2010) Shaun P. Brothers et al. EMBO Molecular Medicine
- Analysis of mouse brain peptides using mass spectrometry-based peptidomics: implications for novel functions ranging from non-classical neuropeptides to microproteins
- (2010) Lloyd D. Fricker Molecular BioSystems
- Increased Abundance of Opioid Receptor Heteromers After Chronic Morphine Administration
- (2010) A. Gupta et al. Science Signaling
- Novel endogenous peptide agonists of cannabinoid receptors
- (2009) Ivone Gomes et al. FASEB JOURNAL
- PROMALS3D: a tool for multiple protein sequence and structure alignments
- (2008) Jimin Pei et al. NUCLEIC ACIDS RESEARCH
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now