NAAG Peptidase Inhibitors Act via mGluR3: Animal Models of Memory, Alzheimer’s, and Ethanol Intoxication
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Title
NAAG Peptidase Inhibitors Act via mGluR3: Animal Models of Memory, Alzheimer’s, and Ethanol Intoxication
Authors
Keywords
<em class=EmphasisTypeItalic >N</em>-Acetylaspartylglutamate, NAAG, Memory, mGluR3 knockout mice, Alzheimer’s mice, Ethanol intoxication, Glutamate carboxypeptidase II, GCPII
Journal
NEUROCHEMICAL RESEARCH
Volume 42, Issue 9, Pages 2646-2657
Publisher
Springer Nature
Online
2017-03-11
DOI
10.1007/s11064-017-2181-4
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- (2017) Steven J. Greco et al. JOURNAL OF ALZHEIMERS DISEASE
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- (2016) Yang Cao et al. BMC NEUROSCIENCE
- Endogenous N-Acetylaspartylglutamate (NAAG) Inhibits Synaptic Plasticity/Transmission in the Amygdala in a Mouse Inflammatory Pain Model
- (2016) Mary O Adedoyin et al. Molecular Pain
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- (2015) Yang Gao et al. JOURNAL OF NEUROCHEMISTRY
- Differential effects of N -acetyl-aspartyl-glutamate on synaptic and extrasynaptic NMDA receptors are subunit- and pH-dependent in the CA1 region of the mouse hippocampus
- (2015) Pamela Khacho et al. NEUROBIOLOGY OF DISEASE
- Spatial Cognition in Adult and Aged Mice Exposed to High-Fat Diet
- (2015) James P. Kesby et al. PLoS One
- mGluR3 knockout mice show a working memory defect and an enhanced response to MK-801 in the T- and Y-maze cognitive tests
- (2014) Mira Lainiola et al. BEHAVIOURAL BRAIN RESEARCH
- Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models
- (2014) Scott J. Webster et al. Frontiers in Genetics
- Episodic-like memory is sensitive to both Alzheimer's-like pathological accumulation and normal ageing processes in mice
- (2013) Katherine E. Davis et al. BEHAVIOURAL BRAIN RESEARCH
- Spatial learning impairments in PLB1Triple knock-in Alzheimer mice are task-specific and age-dependent
- (2013) D. Ryan et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Comprehensive behavioral characterization of an APP/PS-1 double knock-in mouse model of Alzheimer's disease
- (2013) Scott J Webster et al. Alzheimers Research & Therapy
- Growth Hormone–Releasing Hormone Effects on Brain γ-Aminobutyric Acid Levels in Mild Cognitive Impairment and Healthy Aging
- (2013) Seth D. Friedman et al. JAMA Neurology
- Cognitive and non-cognitive behaviors in the triple transgenic mouse model of Alzheimer's disease expressing mutated APP, PS1, and Mapt (3xTg-AD)
- (2012) Mohammed Filali et al. BEHAVIOURAL BRAIN RESEARCH
- Object recognition testing: Statistical considerations
- (2012) Sven Akkerman et al. BEHAVIOURAL BRAIN RESEARCH
- The Role of Glutamate Signaling in Pain Processes and its Regulation by GCP II Inhibition
- (2012) K. M. Wozniak et al. CURRENT MEDICINAL CHEMISTRY
- NAAG peptidase inhibitors and deletion of NAAG peptidase gene enhance memory in novel object recognition test
- (2012) Karolina J. Janczura et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Effects ofN-Acetylaspartylglutamate (NAAG) Peptidase Inhibition on Release of Glutamate and Dopamine in Prefrontal Cortex and Nucleus Accumbens in Phencyclidine Model of Schizophrenia
- (2012) Daiying Zuo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- NAAG Peptidase Inhibition in the Periaqueductal Gray and Rostral Ventromedial Medulla Reduces Flinching in the Formalin Model of Inflammation
- (2012) Toshihiko Yamada et al. Molecular Pain
- Glycine release is regulated by metabotropic glutamate receptors sensitive to mGluR2/3 ligands and activated by N-acetylaspartylglutamate (NAAG)
- (2012) Cristina Romei et al. NEUROPHARMACOLOGY
- Effects of NK-4 in a Transgenic Mouse Model of Alzheimer's Disease
- (2012) Hitomi Ohta et al. PLoS One
- Inhibition of Glutamate Carboxypeptidase II (GCPII) activity as a treatment for cognitive impairment in multiple sclerosis
- (2012) K. A. Rahn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- mGluR3 and not mGluR2 receptors mediate the efficacy of NAAG peptidase inhibitor in validated model of schizophrenia
- (2012) Rafal T. Olszewski et al. SCHIZOPHRENIA RESEARCH
- NAAG peptidase inhibitors block cognitive deficit induced by MK-801 and motor activation induced by d-amphetamine in animal models of schizophrenia
- (2012) R T Olszewski et al. Translational Psychiatry
- Binge Drinking +/- Chronic Nicotine Administration Alters Extracellular Glutamate and Arginine Levels in the Nucleus Accumbens of Adult Male and Female Wistar Rats
- (2011) F. Lallemand et al. ALCOHOL AND ALCOHOLISM
- Ethanol Increases Glutamate Neurotransmission in the Posterior Ventral Tegmental Area of Female Wistar Rats
- (2011) Zheng-Ming Ding et al. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
- Polymorphisms associated with normal memory variation also affect memory impairment in schizophrenia
- (2011) A. Jablensky et al. GENES BRAIN AND BEHAVIOR
- Advances in understanding the peptide neurotransmitter NAAG and appearance of a new member of the NAAG neuropeptide family
- (2011) Joseph H. Neale et al. JOURNAL OF NEUROCHEMISTRY
- N-Acetylaspartylglutamate is an agonist at mGluR3 in vivo and in vitro
- (2011) Joseph H. Neale JOURNAL OF NEUROCHEMISTRY
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- (2011) C. Romberg et al. JOURNAL OF NEUROSCIENCE
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- (2011) Reginald Cannady et al. NEUROPSYCHOPHARMACOLOGY
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- (2011) L. Lyon et al. PSYCHOPHARMACOLOGY
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- (2010) Nimish Sidhpura et al. BIOLOGICAL PSYCHIATRY
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- (2010) Caitlin A. Jones et al. PSYCHOPHARMACOLOGY
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- (2009) M. Chopra et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
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- (2009) Andreas Fahlström et al. NEUROBIOLOGY OF AGING
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- Use of MGLUR2 and MGLUR3 knockout mice to explore in vivo receptor specificity of the MGLUR2/3 selective antagonist LY341495
- (2009) A.-M. Linden et al. NEUROPHARMACOLOGY
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- Age-dependent phenotypic characteristics of a triple transgenic mouse model of Alzheimer disease.
- (2008) Susanna Pietropaolo et al. BEHAVIORAL NEUROSCIENCE
- Synergistic effects of the dopaminergic and glutamatergic system on hippocampal volume in alcohol-dependent patients
- (2008) I. Puls et al. BIOLOGICAL PSYCHOLOGY
- Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice
- (2008) Michael A Mastrangelo et al. BMC NEUROSCIENCE
- Evidence for the Role of Metabotropic Glutamate (mGlu)2 Not mGlu3 Receptors in the Preclinical Antipsychotic Pharmacology of the mGlu2/3 Receptor Agonist (-)-(1R,4S,5S,6S)-4-Amino-2-sulfonylbicyclo[3.1.0]hexane-4,6-dicarboxylic Acid (LY404039)
- (2008) M. J. Fell et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Drugs for relapse prevention of alcoholism: ten years of progress
- (2008) Rainer Spanagel et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Glutamatergic substrates of drug addiction and alcoholism
- (2007) Justin T. Gass et al. BIOCHEMICAL PHARMACOLOGY
- Phencyclidine and Dizocilpine Induced Behaviors Reduced by N-acetylaspartylglutamate Peptidase Inhibition via Metabotropic Glutamate Receptors
- (2007) Rafal T. Olszewski et al. BIOLOGICAL PSYCHIATRY
- Effects of selective inhibition of N-acetylated-α-linked-acidic dipeptidase (NAALADase) on mice in learning and memory tasks
- (2007) Krzysztof Łukawski et al. EUROPEAN JOURNAL OF PHARMACOLOGY
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