Comprehensive behavioral characterization of an APP/PS-1 double knock-in mouse model of Alzheimer's disease

Vascular cognitive impairment and Alzheimer’s disease: role of cerebral hypoperfusion and oxidative stress

(2013) Hyun Ah Kim et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Ferulic Acid Is a Nutraceutical β-Secretase Modulator That Improves Behavioral Impairment and Alzheimer-like Pathology in Transgenic Mice

(2013) Takashi Mori et al.   PLoS One

Cognitive and non-cognitive behaviors in the triple transgenic mouse model of Alzheimer's disease expressing mutated APP, PS1, and Mapt (3xTg-AD)

(2012) Mohammed Filali et al.   BEHAVIOURAL BRAIN RESEARCH

Reduction in neuronal L-type calcium channel activity in a double knock-in mouse model of Alzheimer's disease

(2012) Olivier Thibault et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Characterization of cognitive deficits in a transgenic mouse model of Alzheimer's disease and effects of donepezil and memantine

(2012) Akira Nagakura et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

A truncated peptide from p35, a Cdk5 activator, prevents Alzheimer's disease phenotypes in model mice

(2012) Varsha Shukla et al.   FASEB JOURNAL

Glucagon-Like Peptide-1 Cleavage Product GLP-1(9-36) Amide Rescues Synaptic Plasticity and Memory Deficits in Alzheimer's Disease Model Mice

(2012) T. Ma et al.   JOURNAL OF NEUROSCIENCE

Early Stage Drug Treatment That Normalizes Proinflammatory Cytokine Production Attenuates Synaptic Dysfunction in a Mouse Model That Exhibits Age-Dependent Progression of Alzheimer's Disease-Related Pathology

(2012) A. D. Bachstetter et al.   JOURNAL OF NEUROSCIENCE

Ryanodine Receptor Blockade Reduces Amyloid-  Load and Memory Impairments in Tg2576 Mouse Model of Alzheimer Disease

(2012) B. Oules et al.   JOURNAL OF NEUROSCIENCE

Detecting spatial memory deficits beyond blindness in tg2576 Alzheimer mice

(2012) Nour Yassine et al.   NEUROBIOLOGY OF AGING

ApoE-Directed Therapeutics Rapidly Clear  -Amyloid and Reverse Deficits in AD Mouse Models

(2012) P. E. Cramer et al.   SCIENCE

Age-related increase in amyloid plaque burden is associated with impairment in conditioned fear memory in CRND8 mouse model of amyloidosis

(2012) Amanda Hanna et al.   Alzheimers Research & Therapy

Soluble Aβ levels correlate with cognitive deficits in the 12-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease

(2011) Wei Zhang et al.   BEHAVIOURAL BRAIN RESEARCH

Cognitive phenotyping of amyloid precursor protein transgenic J20 mice

(2011) Tim Karl et al.   BEHAVIOURAL BRAIN RESEARCH

Insulin receptor mutation results in insulin resistance and hyperinsulinemia but does not exacerbate Alzheimer’s-like phenotypes in mice

(2011) Kazuma Murakami et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Multi-faced neuroprotective effects of Ginsenoside Rg1 in an Alzheimer mouse model

(2011) Fang Fang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mouse models of Alzheimer's disease

(2011) Alicia M. Hall et al.   BRAIN RESEARCH BULLETIN

When Is the Hippocampus Involved in Recognition Memory?

(2011) G. R. I. Barker et al.   JOURNAL OF NEUROSCIENCE

Ablation of Cellular Prion Protein Does Not Ameliorate Abnormal Neural Network Activity or Cognitive Dysfunction in the J20 Line of Human Amyloid Precursor Protein Transgenic Mice

(2011) M. Cisse et al.   JOURNAL OF NEUROSCIENCE

Combination therapy prevents amyloid-dependent and -independent structural changes

(2011) Gauri Malthankar-Phatak et al.   NEUROBIOLOGY OF AGING

Cognitive impairment in humanized APP×PS1 mice is linked to Aβ1–42 and NOX activation

(2011) Annadora J. Bruce-Keller et al.   NEUROBIOLOGY OF DISEASE

Mitochondrial dysfunction and accumulation of the β-secretase-cleaved C-terminal fragment of APP in Alzheimer's disease transgenic mice

(2011) Latha Devi et al.   NEUROBIOLOGY OF DISEASE

DHA Improves Cognition and Prevents Dysfunction of Entorhinal Cortex Neurons in 3xTg-AD Mice

(2011) Dany Arsenault et al.   PLoS One

Identification of Low Molecular Weight Pyroglutamate Aβ Oligomers in Alzheimer Disease

(2010) Oliver Wirths et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Many Neuronal and Behavioral Impairments in Transgenic Mouse Models of Alzheimer's Disease Are Independent of Caspase Cleavage of the Amyloid Precursor Protein

(2010) J. A. Harris et al.   JOURNAL OF NEUROSCIENCE

Transgenic Mouse Models of Alzheimer's Disease

(2010) Gregory A. Elder et al.   MOUNT SINAI JOURNAL OF MEDICINE

Age-related loss of phospholipid asymmetry in APPNLh/APPNLh x PS-1P264L/PS-1P264L human double mutant knock-in mice: Relevance to Alzheimer disease

(2010) Miranda L. Bader Lange et al.   NEUROBIOLOGY OF DISEASE

Icariin improves memory impairment in Alzheimer's disease model mice (5xFAD) and attenuates amyloid β-induced neurite atrophy

(2010) Takuya Urano et al.   PHYTOTHERAPY RESEARCH

Visuo-spatial learning and memory deficits on the Barnes maze in the 16-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease

(2009) Timothy P. O’Leary et al.   BEHAVIOURAL BRAIN RESEARCH

Genetic reductions of β-site amyloid precursor protein-cleaving enzyme 1 and amyloid-β ameliorate impairment of conditioned taste aversion memory in 5XFAD Alzheimer’s disease model mice

(2009) Latha Devi et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Amyloid β and impairment in multiple memory systems in older transgenic APP TgCRND8 mice

(2009) A. Hanna et al.   GENES BRAIN AND BEHAVIOR

Age-Dependent Impairment of Spine Morphology and Synaptic Plasticity in Hippocampal CA1 Neurons of a Presenilin 1 Transgenic Mouse Model of Alzheimer's Disease

(2009) A. Auffret et al.   JOURNAL OF NEUROSCIENCE

Morphological alterations to neurons of the amygdala and impaired fear conditioning in a transgenic mouse model of Alzheimer's disease

(2009) Shira Knafo et al.   JOURNAL OF PATHOLOGY

Cyclophilin D deficiency improves mitochondrial function and learning/memory in aging Alzheimer disease mouse model

(2009) Heng Du et al.   NEUROBIOLOGY OF AGING

Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease

(2009) J. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wheel-running in a transgenic mouse model of Alzheimer's disease: Protection or symptom?

(2008) Helene Richter et al.   BEHAVIOURAL BRAIN RESEARCH

Effects of the genetic background on cognitive performances of TG2576 mice

(2008) Jean Michel Lassalle et al.   BEHAVIOURAL BRAIN RESEARCH

Effects of environmental enrichment on exploration, anxiety, and memory in female TgCRND8 Alzheimer mice

(2008) Nicole Görtz et al.   BEHAVIOURAL BRAIN RESEARCH

Validation of a 2-day water maze protocol in mice

(2008) Maria Gulinello et al.   BEHAVIOURAL BRAIN RESEARCH

Rosiglitazone reverses memory decline and hippocampal glucocorticoid receptor down-regulation in an Alzheimer’s disease mouse model

(2008) Luis Escribano et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oxidative damage in brain from human mutant APP/PS-1 double knock-in mice as a function of age

(2008) Hafiz Mohmmad Abdul et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effects of short-term Western diet on cerebral oxidative stress and diabetes related factors in APP × PS1 knock-in mice

(2008) Christa M. Studzinski et al.   JOURNAL OF NEUROCHEMISTRY

Enkephalin Elevations Contribute to Neuronal and Behavioral Impairments in a Transgenic Mouse Model of Alzheimer's Disease

(2008) W. J. Meilandt et al.   JOURNAL OF NEUROSCIENCE

Retinoic Acid Attenuates  -Amyloid Deposition and Rescues Memory Deficits in an Alzheimer's Disease Transgenic Mouse Model

(2008) Y. Ding et al.   JOURNAL OF NEUROSCIENCE

Dynamic Changes in the Recovery after Traumatic Brain Injury in Mice: Effect of Injury Severity on T2-Weighted MRI Abnormalities, and Motor and Cognitive Functions

(2008) Jeanna Tsenter et al.   JOURNAL OF NEUROTRAUMA

Faster forgetting contributes to impaired spatial memory in the PDAPP mouse: Deficit in memory retrieval associated with increased sensitivity to interference?

(2008) S. Daumas et al.   LEARNING & MEMORY

Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease

(2008) Rene O Sanchez-Mejia et al.   NATURE NEUROSCIENCE

Elimination of GD3 synthase improves memory and reduces amyloid-β plaque load in transgenic mice

(2008) Alexandra Bernardo et al.   NEUROBIOLOGY OF AGING

Levodopa ameliorates learning and memory deficits in a murine model of Alzheimer’s disease

(2008) Oliver Ambrée et al.   NEUROBIOLOGY OF AGING

Episodic memory deficits are not related to altered glutamatergic synaptic transmission and plasticity in the CA1 hippocampus of the APPswe/PS1ΔE9-deleted transgenic mice model of β-amyloidosis

(2008) Arturas Volianskis et al.   NEUROBIOLOGY OF AGING

Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model

(2008) Ryoichi Kimura et al.   NEUROBIOLOGY OF DISEASE

Overexpression of wild-type human APP in mice causes cognitive deficits and pathological features unrelated to Aβ levels

(2008) Ana-María Simón et al.   NEUROBIOLOGY OF DISEASE

Behavioral Phenotyping Strategies for Mutant Mice

(2008) Jacqueline N. Crawley   NEURON