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Title
The potential of organoids in urological cancer research
Authors
Keywords
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Journal
Nature Reviews Urology
Volume 14, Issue 7, Pages 401-414
Publisher
Springer Nature
Online
2017-05-23
DOI
10.1038/nrurol.2017.65
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Note: Only part of the references are listed.- A 3D in vitro model of patient-derived prostate cancer xenograft for controlled interrogation of in vivo tumor-stromal interactions
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- (2016) Jonathan E Rosenberg et al. LANCET
- Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer
- (2016) Akash Kumar et al. NATURE MEDICINE
- Generation of kidney organoids from human pluripotent stem cells
- (2016) Minoru Takasato et al. Nature Protocols
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- (2016) Jarno Drost et al. Nature Protocols
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- (2016) NEW ENGLAND JOURNAL OF MEDICINE
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- (2016) Jung Wook Park et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Low CD38 Identifies Progenitor-like Inflammation-Associated Luminal Cells that Can Initiate Human Prostate Cancer and Predict Poor Outcome
- (2016) Xian Liu et al. Cell Reports
- Integrative Clinical Genomics of Advanced Prostate Cancer
- (2015) Dan Robinson et al. CELL
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- (2015) Meritxell Huch et al. CELL
- Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients
- (2015) Marc van de Wetering et al. CELL
- Organoid Models of Human and Mouse Ductal Pancreatic Cancer
- (2015) Sylvia F. Boj et al. CELL
- The Molecular Taxonomy of Primary Prostate Cancer
- (2015) Adam Abeshouse et al. CELL
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- (2015) Suk Hyung Lee et al. CURRENT OPINION IN CELL BIOLOGY
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- (2015) M. Takasato et al. DEVELOPMENT
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- (2015) Alexandre Calon et al. NATURE GENETICS
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- (2015) Paul C Boutros et al. NATURE GENETICS
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- (2015) P. Sharma et al. SCIENCE
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- (2015) Supreet Agarwal et al. Cell Reports
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- Directed Differentiation of Human Embryonic Stem Cells into Prostate Organoids In Vitro and its Perturbation by Low-Dose Bisphenol A Exposure
- (2015) Esther L. Calderon-Gierszal et al. PLoS One
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- (2014) Francesca Gattazzo et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
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- (2014) Caleb F. Davis et al. CANCER CELL
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- (2012) Shiro Yui et al. NATURE MEDICINE
- Mammalian Kidney Development: Principles, Progress, and Projections
- (2012) M. H. Little et al. Cold Spring Harbor Perspectives in Biology
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
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- (2011) Xuefeng Liu et al. AMERICAN JOURNAL OF PATHOLOGY
- Mouse Models of Cancer
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- (2011) Toshiro Sato et al. GASTROENTEROLOGY
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- (2011) Jianjian Zhu et al. GENESIS
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- (2011) F. Dayyani et al. JNCI-Journal of the National Cancer Institute
- Self-formation of functional adenohypophysis in three-dimensional culture
- (2011) Hidetaka Suga et al. NATURE
- Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder
- (2011) Kunyoo Shin et al. NATURE
- Self-organizing optic-cup morphogenesis in three-dimensional culture
- (2011) Mototsugu Eiraku et al. NATURE
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- (2011) H. Beltran et al. Cancer Discovery
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- (2010) Nick Barker et al. Cell Stem Cell
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- (2010) Maria Håkanson et al. Integrative Biology
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- (2010) Sandra Chapman et al. JOURNAL OF CLINICAL INVESTIGATION
- A molecular network for de novo generation of the apical surface and lumen
- (2010) David M. Bryant et al. NATURE CELL BIOLOGY
- Basal epithelial stem cells are efficient targets for prostate cancer initiation
- (2010) D. A. Lawson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment
- (2009) Britta Weigelt et al. BREAST CANCER RESEARCH AND TREATMENT
- A luminal epithelial stem cell that is a cell of origin for prostate cancer
- (2009) Xi Wang et al. NATURE
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- (2009) Brett S Carver et al. NATURE GENETICS
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- Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidney
- (2008) Joshua W. Mugford et al. DEVELOPMENTAL BIOLOGY
- FGF-8 is involved in bone metastasis of prostate cancer
- (2008) Maija P. Valta et al. INTERNATIONAL JOURNAL OF CANCER
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