Cell Therapy Using Human Induced Pluripotent Stem Cell-Derived Renal Progenitors Ameliorates Acute Kidney Injury in Mice

Renal progenitors derived from human iPSCs engraft and restore function in a mouse model of acute kidney injury

(2015) Barbara Imberti et al.   Scientific Reports

Osr1 acts downstream of and interacts synergistically with Six2 to maintain nephron progenitor cells during kidney organogenesis

(2014) J. Xu et al.   DEVELOPMENT

Acute Kidney Injury and Chronic Kidney Disease as Interconnected Syndromes

(2014) Lakhmir S. Chawla et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficient and Rapid Induction of Human iPSCs/ESCs into Nephrogenic Intermediate Mesoderm Using Small Molecule-Based Differentiation Methods

(2014) Toshikazu Araoka et al.   PLoS One

Differentiation of Human Pluripotent Stem Cells into Nephron Progenitor Cells in a Serum and Feeder Free System

(2014) Minyong Kang et al.   PLoS One

Mesenchymal stem cells, not conditioned medium, contribute to kidney repair after ischemia-reperfusion injury

(2014) Li Xing et al.   Stem Cell Research & Therapy

Redefining the In Vivo Origin of Metanephric Nephron Progenitors Enables Generation of Complex Kidney Structures from Pluripotent Stem Cells

(2013) Atsuhiro Taguchi et al.   Cell Stem Cell

Identification of human nephron progenitors capable of generation of kidney structures and functional repair of chronic renal disease

(2013) Orit Harari-Steinberg et al.   EMBO Molecular Medicine

Rapid and Efficient Differentiation of Human Pluripotent Stem Cells into Intermediate Mesoderm That Forms Tubules Expressing Kidney Proximal Tubular Markers

(2013) A. Q. Lam et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Renal Cells from Spermatogonial Germline Stem Cells Protect against Kidney Injury

(2013) L. De Chiara et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney

(2013) M. Takasato et al.   NATURE CELL BIOLOGY

Acute kidney injury: an intensivist’s perspective

(2013) John R. Prowle   PEDIATRIC NEPHROLOGY

Role for compartmentalization in nephron progenitor differentiation

(2013) A. C. Brown et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells

(2013) Shin-Ichi Mae et al.   Nature Communications

Rationale of Mesenchymal Stem Cell Therapy in Kidney Injury

(2012) Vincenzo Cantaluppi et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

FGF9 and FGF20 Maintain the Stemness of Nephron Progenitors in Mice and Man

(2012) Hila Barak et al.   DEVELOPMENTAL CELL

Six2 and Wnt Regulate Self-Renewal and Commitment of Nephron Progenitors through Shared Gene Regulatory Networks

(2012) Joo-Seop Park et al.   DEVELOPMENTAL CELL

Mycophenolate mofetil inhibits macrophage infiltration and kidney fibrosis in long-term ischemia–reperfusion injury

(2012) Shuai Jiang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Microvesicles derived from endothelial progenitor cells protect the kidney from ischemia–reperfusion injury by microRNA-dependent reprogramming of resident renal cells

(2012) Vincenzo Cantaluppi et al.   KIDNEY INTERNATIONAL

Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells

(2012) M. Kajiwara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Efficient Nonviral Method to Generate Integration-Free Human-Induced Pluripotent Stem Cells from Cord Blood and Peripheral Blood Cells

(2012) Keisuke Okita et al.   STEM CELLS

Exosomes/microvesicles as a mechanism of cell-to-cell communication

(2010) Giovanni Camussi et al.   KIDNEY INTERNATIONAL

In VivoStructure−Activity Relationship Study of Dorsomorphin Analogues Identifies Selective VEGF and BMP Inhibitors

(2009) Jijun Hao et al.   ACS Chemical Biology

Congenital DNA repair deficiency results in protection against renal ischemia reperfusion injury in mice

(2009) Denis Susa et al.   AGING CELL

IRF-1 Promotes Inflammation Early after Ischemic Acute Kidney Injury

(2009) Y. Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Dissociation of embryonic kidneys followed by reaggregation allows the formation of renal tissues

(2009) Mathieu Unbekandt et al.   KIDNEY INTERNATIONAL

Six2 Defines and Regulates a Multipotent Self-Renewing Nephron Progenitor Population throughout Mammalian Kidney Development

(2008) Akio Kobayashi et al.   Cell Stem Cell

Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidney

(2008) Joshua W. Mugford et al.   DEVELOPMENTAL BIOLOGY

SIX2 and BMP4 Mutations Associate With Anomalous Kidney Development

(2008) S. Weber et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Marked differences in differentiation propensity among human embryonic stem cell lines

(2008) Kenji Osafune et al.   NATURE BIOTECHNOLOGY