Conformational dynamics of a G-protein α subunit is tightly regulated by nucleotide binding

Universal allosteric mechanism for Gα activation by GPCRs

(2015) Tilman Flock et al.   NATURE

A cleavable ligand column for the rapid isolation of large quantities of homogeneous and functional neurotensin receptor 1 variants from E. coli

(2015) Pascal Egloff et al.   PROTEIN EXPRESSION AND PURIFICATION

Structural basis for nucleotide exchange in heterotrimeric G proteins

(2015) R. O. Dror et al.   SCIENCE

Improving the apo-state detergent stability of NTS1 with CHESS for pharmacological and structural studies

(2014) Daniel J. Scott et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Structure of signaling-competent neurotensin receptor 1 obtained by directed evolution inEscherichia coli

(2014) Pascal Egloff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optimized Phospholipid Bilayer Nanodiscs Facilitate High-Resolution Structure Determination of Membrane Proteins

(2013) Franz Hagn et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Energetic analysis of the rhodopsin–G-protein complex links the α5 helix to GDP release

(2013) Nathan S Alexander et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cell-free Expressed Bacteriorhodopsin in Different Soluble Membrane Mimetics: Biophysical Properties and NMR Accessibility

(2013) Manuel Etzkorn et al.   STRUCTURE

New developments in theATSASprogram package for small-angle scattering data analysis

(2012) Maxim V. Petoukhov et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Application of iterative soft thresholding for fast reconstruction of NMR data non-uniformly sampled with multidimensional Poisson Gap scheduling

(2012) Sven G. Hyberts et al.   JOURNAL OF BIOMOLECULAR NMR

Critical features for biosynthesis, stability, and functionality of a G protein-coupled receptor uncovered by all-versus-all mutations

(2012) K. M. Schlinkmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression, purification and preliminary NMR characterization of isotopically labeled wild-type human heterotrimeric G protein αi1

(2012) Jan Maly et al.   PROTEIN EXPRESSION AND PURIFICATION

relaxGUI: a new software for fast and simple NMR relaxation data analysis and calculation of ps-ns and μs motion of proteins

(2011) Michael Bieri et al.   JOURNAL OF BIOMOLECULAR NMR

LigPlot+: Multiple Ligand–Protein Interaction Diagrams for Drug Discovery

(2011) Roman A. Laskowski et al.   Journal of Chemical Information and Modeling

Crystal structure of the β2 adrenergic receptor–Gs protein complex

(2011) Søren G. F. Rasmussen et al.   NATURE

Poisson-Gap Sampling and Forward Maximum Entropy Reconstruction for Enhancing the Resolution and Sensitivity of Protein NMR Data

(2010) Sven G. Hyberts et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Relaxation Dispersion NMR Spectroscopy as a Tool for Detailed Studies of Protein Folding

(2009) Philipp Neudecker et al.   BIOPHYSICAL JOURNAL

Overcoming the solubility limit with solubility-enhancement tags: successful applications in biomolecular NMR studies

(2009) Pei Zhou et al.   JOURNAL OF BIOMOLECULAR NMR

Characterization of Enzyme Motions by Solution NMR Relaxation Dispersion

(2008) J. Patrick Loria et al.   ACCOUNTS OF CHEMICAL RESEARCH

NMR: prediction of molecular alignment from structure using the PALES software

(2008) Markus Zweckstetter   Nature Protocols

Directed evolution of a G protein-coupled receptor for expression, stability, and binding selectivity

(2008) C. A. Sarkar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA