An Annular Lipid Belt Is Essential for Allosteric Coupling and Viral Inhibition of the Antigen Translocation Complex TAP (Transporter Associated with Antigen Processing)

ABC transporters in adaptive immunity

(2015) Fabian Seyffer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Nucleotide-free MalK Drives the Transition of the Maltose Transporter to the Inward-facing Conformation

(2014) Huan Bao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformational dynamics of the nucleotide binding domains and the power stroke of a heterodimeric ABC transporter

(2014) Smriti Mishra et al.   eLife

Radioligand Binding to Nanodisc-Reconstituted Membrane Transporters Assessed by the Scintillation Proximity Assay

(2013) Mahmoud L. Nasr et al.   BIOCHEMISTRY

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

(2013) Sander Pronk et al.   BIOINFORMATICS

Physicochemical Factors Controlling the Activity and Energy Coupling of an Ionic Strength-gated ATP-binding Cassette (ABC) Transporter

(2013) Akira Karasawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Optimized Phospholipid Bilayer Nanodiscs Facilitate High-Resolution Structure Determination of Membrane Proteins

(2013) Franz Hagn et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multicolour Fluorescence-Detection Size-Exclusion Chromatography for Structural Genomics of Membrane Multiprotein Complexes

(2013) David Parcej et al.   PLoS One

The MHC I loading complex: a multitasking machinery in adaptive immunity

(2013) Sabine Hulpke et al.   TRENDS IN BIOCHEMICAL SCIENCES

Characterization of co-translationally formed nanodisc complexes with small multidrug transporters, proteorhodopsin and with the E. coli MraY translocase

(2012) Christian Roos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Modified lipid and protein dynamics in nanodiscs

(2012) Karsten Mörs et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Direct evidence that the N-terminal extensions of the TAP complex act as autonomous interaction scaffolds for the assembly of the MHC I peptide-loading complex

(2012) Sabine Hulpke et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

An Extension and Further Validation of an All-Atomistic Force Field for Biological Membranes

(2012) Joakim P. M. Jämbeck et al.   Journal of Chemical Theory and Computation

Derivation and Systematic Validation of a Refined All-Atom Force Field for Phosphatidylcholine Lipids

(2012) Joakim P. M. Jämbeck et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Discovery of an Auto-Regulation Mechanism for the Maltose ABC Transporter MalFGK2

(2012) Huan Bao et al.   PLoS One

Molecular Interaction Studies Using Microscale Thermophoresis

(2011) Moran Jerabek-Willemsen et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Catalytic activity of MsbA reconstituted in nanodisc particles is modulated by remote interactions with the bilayer

(2011) Takeaki Kawai et al.   FEBS LETTERS

Specific Lipids Modulate the Transporter Associated with Antigen Processing (TAP)

(2011) Christian Schölz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformational Analysis of Human ATP-binding Cassette Transporter ABCB1 in Lipid Nanodiscs and Inhibition by the Antibodies MRK16 and UIC2

(2011) Tasha K. Ritchie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cryo-EM structure of the ribosome–SecYE complex in the membrane environment

(2011) Jens Frauenfeld et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Conformation of peptides bound to the transporter associated with antigen processing (TAP)

(2011) M. Herget et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ABC proteins in antigen translocation and viral inhibition

(2010) David Parcej et al.   Nature Chemical Biology

Improved side-chain torsion potentials for the Amber ff99SB protein force field

(2010) Kresten Lindorff-Larsen et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Protein-binding assays in biological liquids using microscale thermophoresis

(2010) Christoph J. Wienken et al.   Nature Communications

The mechanism of ABC transporters: general lessons from structural and functional studies of an antigenic peptide transporter

(2009) Erik Procko et al.   FASEB JOURNAL

Membrane protein assembly into Nanodiscs

(2009) Timothy H. Bayburt et al.   FEBS LETTERS

Purification and Reconstitution of the Antigen Transport Complex TAP

(2009) Meike Herget et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ABC transporters: the power to change

(2009) Douglas C. Rees et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural arrangement of the transmission interface in the antigen ABC transport complex TAP

(2009) G. Oancea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA