Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes

Human islets and dendritic cells generate post-translationally modified islet autoantigens

(2016) R. J. McLaughlin et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Dendritic Cells Guide Islet Autoimmunity through a Restricted and Uniquely Processed Peptidome Presented by High-Risk HLA-DR

(2016) Menno van Lummel et al.   JOURNAL OF IMMUNOLOGY

Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion

(2016) T. Delong et al.   SCIENCE

Neoantigens and Microenvironment in Type 1 Diabetes: Lessons from Antitumor Immunity

(2016) Maria J.L. Kracht et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Discovery of a Selective Islet Peptidome Presented by the Highest-Risk HLA-DQ8transMolecule

(2015) Menno van Lummel et al.   DIABETES

Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers

(2015) Suna Onengut-Gumuscu et al.   NATURE GENETICS

Large-Scale Characterization of Natural Ligands Explains the Unique Gluten-Binding Properties of HLA-DQ2

(2014) D. Stepniak et al.   JOURNAL OF IMMUNOLOGY

Translating DRiPs: MHC class I immunosurveillance of pathogens and tumors

(2014) L. C. Anton et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Posttranslational Modification of HLA-DQ Binding Islet Autoantigens in Type 1 Diabetes

(2013) M. van Lummel et al.   DIABETES

Genetically Engineered Human Islets Protected From CD8-mediated Autoimmune Destruction In Vivo

(2013) Arnaud Zaldumbide et al.   MOLECULAR THERAPY

Changing faces, unmasking the beta-cell

(2013) Menno van Lummel et al.   Current Opinion in Endocrinology Diabetes and Obesity

CD8 T cell autoreactivity to preproinsulin epitopes with very low human leucocyte antigen class I binding affinity

(2012) J. R. F. Abreu et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

ER Stress as a Trigger for  -Cell Dysfunction and Autoimmunity in Type 1 Diabetes

(2012) B. O'Sullivan-Murphy et al.   DIABETES

Circulating Preproinsulin Signal Peptide-Specific CD8 T Cells Restricted by the Susceptibility Molecule HLA-A24 Are Expanded at Onset of Type 1 Diabetes and Kill  -Cells

(2012) D. Kronenberg et al.   DIABETES

Post-transcriptional control of candidate risk genes for type 1 diabetes by rare genetic variants

(2012) V M de Jong et al.   GENES AND IMMUNITY

Pancreas Organ Weight in Individuals With Disease-Associated Autoantibodies at Risk for Type 1 Diabetes

(2012) Martha Campbell-Thompson et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

(2012) Ken T. Coppieters et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Amsterdamming DRiPs

(2012) Jonathan W. Yewdell   MOLECULAR IMMUNOLOGY

The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines

(2012) Décio L. Eizirik et al.   PLoS Genetics

Non-conventional sources of peptides presented by MHC class I

(2011) Shelley R. Starck et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Type 1 Diabetes-associated HLA-DQ8 Transdimer Accommodates a Unique Peptide Repertoire

(2011) Menno van Lummel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Simultaneous Detection of Circulating Autoreactive CD8+ T-Cells Specific for Different Islet Cell-Associated Epitopes Using Combinatorial MHC Multimers

(2010) J. H. Velthuis et al.   DIABETES

Role of a ribosome-associated E3 ubiquitin ligase in protein quality control

(2010) Mario H. Bengtson et al.   NATURE

Induction of Treg by monocyte-derived DC modulated by vitamin D3or dexamethasone: Differential role for PD-L1

(2009) Wendy W. J. Unger et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families

(2009) J M M Howson et al.   GENES AND IMMUNITY

Translationally Optimal Codons Associate with Structurally Sensitive Sites in Proteins

(2009) T. Zhou et al.   MOLECULAR BIOLOGY AND EVOLUTION

The role of inflammation in insulitis and β-cell loss in type 1 diabetes

(2009) Décio L. Eizirik et al.   Nature Reviews Endocrinology

Insulin as an autoantigen in NOD/human diabetes

(2008) Li Zhang et al.   CURRENT OPINION IN IMMUNOLOGY

The Unfolded Protein Response: A Pathway That Links Insulin Demand with β-Cell Failure and Diabetes

(2008) Donalyn Scheuner et al.   ENDOCRINE REVIEWS

A Distinct Translation Initiation Mechanism Generates Cryptic Peptides for Immune Surveillance

(2008) Shelley R. Starck et al.   PLoS One