Human islets and dendritic cells generate post-translationally modified islet autoantigens

Role of dendritic cells in the initiation, progress and modulation of systemic autoimmune diseases

(2015) Juan Pablo Mackern-Oberti et al.   AUTOIMMUNITY REVIEWS

Proinsulin multi-peptide immunotherapy induces antigen-specific regulatory T cells and limits autoimmunity in a humanized model

(2015) V. B. Gibson et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Discovery of a Selective Islet Peptidome Presented by the Highest-Risk HLA-DQ8transMolecule

(2015) Menno van Lummel et al.   DIABETES

Innate and adaptive immunity to human beta cell lines: implications for beta cell therapy

(2015) Cornelis R. van der Torren et al.   DIABETOLOGIA

The Role of Dendritic Cell Subsets and Innate Immunity in the Pathogenesis of Type 1 Diabetes and Other Autoimmune Diseases

(2015) Jeffrey D. Price et al.   Frontiers in Immunology

Self-Antigen Expression in the Peripheral Immune System: Roles in Self-Tolerance and Type 1 Diabetes Pathogenesis

(2014) Rebecca Fuhlbrigge et al.   Current Diabetes Reports

Proinsulin-Specific, HLA-DQ8, and HLA-DQ8-Transdimer–Restricted CD4+T Cells Infiltrate Islets in Type 1 Diabetes

(2014) Vimukthi Pathiraja et al.   DIABETES

Anakinra and Tocilizumab Enhance Survival and Function of Human Islets during Culture: Implications for Clinical Islet Transplantation

(2013) Afaf Sahraoui et al.   CELL TRANSPLANTATION

Dendritic cells in tolerance and autoimmune diabetes

(2013) Sylvie Guerder et al.   CURRENT OPINION IN IMMUNOLOGY

Posttranslational Modification of HLA-DQ Binding Islet Autoantigens in Type 1 Diabetes

(2013) M. van Lummel et al.   DIABETES

Genetically Engineered Human Islets Protected From CD8-mediated Autoimmune Destruction In Vivo

(2013) Arnaud Zaldumbide et al.   MOLECULAR THERAPY

Changing faces, unmasking the beta-cell

(2013) Menno van Lummel et al.   Current Opinion in Endocrinology Diabetes and Obesity

Transglutaminase 2 transamidation activity during first-phase insulin secretion: natural substrates in INS-1E

(2012) Lucia Russo et al.   ACTA DIABETOLOGICA

Tolerogenic dendritic cells impede priming of naïve CD8+T cells and deplete memory CD8+T cells

(2012) Fleur S. Kleijwegt et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

(2012) Ken T. Coppieters et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Type 1 Diabetes-associated HLA-DQ8 Transdimer Accommodates a Unique Peptide Repertoire

(2011) Menno van Lummel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Protein Pathways in 1,25-Dihydroxyvitamin D3 and Dexamethasone Modulated Tolerogenic Human Dendritic Cells

(2011) Gabriela Bomfim Ferreira et al.   JOURNAL OF PROTEOME RESEARCH

Islet inflammation and CXCL10 in recent-onset type 1 diabetes

(2010) B. O. Roep et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Induction of Treg by monocyte-derived DC modulated by vitamin D3or dexamethasone: Differential role for PD-L1

(2009) Wendy W. J. Unger et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Transglutaminase 2 is expressed and active on the surface of human monocyte-derived dendritic cells and macrophages

(2009) Judit Hodrea et al.   IMMUNOLOGY LETTERS

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

Analysis of islet inflammation in human type 1 diabetes

(2008) A. Willcox et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY