Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis

Desmoplakin Variants Are Associated with Idiopathic Pulmonary Fibrosis

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Exome Array Analysis Identifies a Common Variant inIL27Associated with Chronic Obstructive Pulmonary Disease

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Genome-wide imputation study identifies novel HLA locus for pulmonary fibrosis and potential role for auto-immunity in fibrotic idiopathic interstitial pneumonia

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Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis–emphysema

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Integrative Tissue-Specific Functional Annotations in the Human Genome Provide Novel Insights on Many Complex Traits and Improve Signal Prioritization in Genome Wide Association Studies

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Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci

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Leveraging Multi-ethnic Evidence for Mapping Complex Traits in Minority Populations: An Empirical Bayes Approach

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Leveraging Functional-Annotation Data in Trans-ethnic Fine-Mapping Studies

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A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes

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Suppression of NLRX1 in chronic obstructive pulmonary disease

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Genetic studies of body mass index yield new insights for obesity biology

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Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture

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Partitioning heritability by functional annotation using genome-wide association summary statistics

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LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

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HaploReg v4: systematic mining of putative causal variants, cell types, regulators and target genes for human complex traits and disease

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Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

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Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank

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Second-generation PLINK: rising to the challenge of larger and richer datasets

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A Common 16p11.2 Inversion Underlies the Joint Susceptibility to Asthma and Obesity

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SNPsea: an algorithm to identify cell types, tissues and pathways affected by risk loci

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The clinical and genetic features of COPD-asthma overlap syndrome

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Telomerase mutations in smokers with severe emphysema

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Defining the role of common variation in the genomic and biological architecture of adult human height

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Selecting causal genes from genome-wide association studies via functionally coherent subnetworks

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Quality control and conduct of genome-wide association meta-analyses

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Gene Ontology Consortium: going forward

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Genetic regulation of gene expression in the lung identifiesCST3andCD22as potential causal genes for airflow obstruction

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MTCL1 crosslinks and stabilizes non-centrosomal microtubules on the Golgi membrane

(2014) Yoshinori Sato et al.   Nature Communications

Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics

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Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis

(2014) Michael H Cho et al.   Lancet Respiratory Medicine

The NLR protein, NLRX1, and its partner, TUFM, reduce type I interferon, and enhance autophagy

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The novel PAR-1-binding protein MTCL1 has crucial roles in organizing microtubules in polarizing epithelial cells

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Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis

(2013) Tasha E Fingerlin et al.   NATURE GENETICS

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

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Refining Susceptibility Loci of Chronic Obstructive Pulmonary Disease with Lung eqtls

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Genome-Wide Association Studies IdentifyCHRNA5/3andHTR4in the Development of Airflow Obstruction

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Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease

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Molecular Signature of Smoking in Human Lung Tissues

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The Mitochondrial Proteins NLRX1 and TUFM Form a Complex that Regulates Type I Interferon and Autophagy

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Large-scale association analysis identifies new risk loci for coronary artery disease

(2012) Panos Deloukas et al.   NATURE GENETICS

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

(2012) Jian Yang et al.   NATURE GENETICS

The pathogenesis of COPD and IPF: Distinct horns of the same devil?

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Lung eQTLs to Help Reveal the Molecular Underpinnings of Asthma

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Genome-Wide Joint Meta-Analysis of SNP and SNP-by-Smoking Interaction Identifies Novel Loci for Pulmonary Function

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The Association of Genome-Wide Significant Spirometric Loci with Chronic Obstructive Pulmonary Disease Susceptibility

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Opportunities and Challenges in the Genetics of COPD 2010: An International COPD Genetics Conference Report

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Transethnic meta-analysis of genomewide association studies

(2011) Andrew P. Morris   GENETIC EPIDEMIOLOGY

A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13

(2011) M. H. Cho et al.   HUMAN MOLECULAR GENETICS

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

(2011) María Soler Artigas et al.   NATURE GENETICS

Lung Volumes and Emphysema in Smokers with Interstitial Lung Abnormalities

(2011) George R. Washko et al.   NEW ENGLAND JOURNAL OF MEDICINE

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

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GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Polymorphisms in Surfactant Protein–D Are Associated with Chronic Obstructive Pulmonary Disease

(2010) Marilyn G. Foreman et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

METAL: fast and efficient meta-analysis of genomewide association scans

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Sequence variants at CHRNB3–CHRNA6 and CYP2A6 affect smoking behavior

(2010) Thorgeir E Thorgeirsson et al.   NATURE GENETICS

Genome-wide meta-analyses identify multiple loci associated with smoking behavior

(2010)   NATURE GENETICS

Variants in FAM13A are associated with chronic obstructive pulmonary disease

(2010) Michael H Cho et al.   NATURE GENETICS

A Large-Scale, Consortium-Based Genomewide Association Study of Asthma

(2010) Miriam F. Moffatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

i-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study

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Serum surfactant protein D is steroid sensitive and associated with exacerbations of COPD

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Genome-wide association study identifies five loci associated with lung function

(2009) Emmanouela Repapi et al.   NATURE GENETICS

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function

(2009) Dana B Hancock et al.   NATURE GENETICS

A Genome-Wide Association Study of Pulmonary Function Measures in the Framingham Heart Study

(2009) Jemma B. Wilk et al.   PLoS Genetics

A Genome-Wide Investigation of SNPs and CNVs in Schizophrenia

(2009) Anna C. Need et al.   PLoS Genetics

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Bayes factors for genome-wide association studies: comparison withP-values

(2008) Jon Wakefield   GENETIC EPIDEMIOLOGY