Exome Array Analysis Identifies a Common Variant inIL27Associated with Chronic Obstructive Pulmonary Disease

Control for Population Structure and Relatedness for Binary Traits in Genetic Association Studies via Logistic Mixed Models

(2016) Han Chen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes

(2015) Michael H. Cho et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Immunobiology of Interleukin-27

(2015) Hiroki Yoshida et al.   Annual Review of Immunology

Suppression of NLRX1 in chronic obstructive pulmonary disease

(2015) Min-Jong Kang et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

(2015) Jennifer Wessel et al.   Nature Communications

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

A Common 16p11.2 Inversion Underlies the Joint Susceptibility to Asthma and Obesity

(2014) Juan R. González et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Association of Low-Frequency and Rare Coding-Sequence Variants with Blood Lipids and Coronary Heart Disease in 56,000 Whites and Blacks

(2014) Gina M. Peloso et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Beyond GWAS in COPD: Probing the Landscape between Gene-Set Associations, Genome-Wide Associations and Protein-Protein Interaction Networks

(2014) Merry-Lynn Noelle McDonald et al.   HUMAN HEREDITY

Genetic control of gene expression at novel and established chronic obstructive pulmonary disease loci

(2014) Peter J. Castaldi et al.   HUMAN MOLECULAR GENETICS

A general framework for estimating the relative pathogenicity of human genetic variants

(2014) Martin Kircher et al.   NATURE GENETICS

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

(2014) Jason Flannick et al.   NATURE GENETICS

Minor histocompatibility antigens: past, present, and future

(2014) Eric Spierings   TISSUE ANTIGENS

Non-emphysematous chronic obstructive pulmonary disease is associated with diabetes mellitus

(2014) Craig P Hersh et al.   BMC Pulmonary Medicine

Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis

(2014) Michael H Cho et al.   Lancet Respiratory Medicine

Update in Chronic Obstructive Pulmonary Disease 2012

(2013) MeiLan K. Han et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Heritability of Chronic Obstructive Pulmonary Disease and Related Phenotypes in Smokers

(2013) Jin J. Zhou et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The NLR protein, NLRX1, and its partner, TUFM, reduce type I interferon, and enhance autophagy

(2013) Yu Lei et al.   Autophagy

APOM and high-density lipoprotein cholesterol are associated with lung function and per cent emphysema

(2013) K. M. Burkart et al.   EUROPEAN RESPIRATORY JOURNAL

Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility

(2013) Mateusz Siedlinski et al.   HUMAN GENETICS

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Pleiotropy in complex traits: challenges and strategies

(2013) Nadia Solovieff et al.   NATURE REVIEWS GENETICS

Optimal Unified Approach for Rare-Variant Association Testing with Application to Small-Sample Case-Control Whole-Exome Sequencing Studies

(2012) Seunggeun Lee et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-Wide Association Studies IdentifyCHRNA5/3andHTR4in the Development of Airflow Obstruction

(2012) Jemma B. Wilk et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease

(2012) Jørgen Vestbo et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Mitochondrial Proteins NLRX1 and TUFM Form a Complex that Regulates Type I Interferon and Autophagy

(2012) Yu Lei et al.   IMMUNITY

Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion

(2012) Jeroen R Huyghe et al.   NATURE GENETICS

Genome-Wide Joint Meta-Analysis of SNP and SNP-by-Smoking Interaction Identifies Novel Loci for Pulmonary Function

(2012) Dana B. Hancock et al.   PLoS Genetics

Rare-Variant Association Testing for Sequencing Data with the Sequence Kernel Association Test

(2011) Michael C. Wu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

IL-27 Is Elevated in Patients With COPD and Patients With Pulmonary TB and Induces Human Bronchial Epithelial Cells to Produce CXCL10

(2011) Ju Cao et al.   CHEST

A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13

(2011) M. H. Cho et al.   HUMAN MOLECULAR GENETICS

The G82S Polymorphism Promotes Glycosylation of the Receptor for Advanced Glycation End Products (RAGE) at Asparagine 81

(2011) Sun Jin Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

(2011) María Soler Artigas et al.   NATURE GENETICS

Genome-Wide Association Analysis of Autoantibody Positivity in Type 1 Diabetes Cases

(2011) Vincent Plagnol et al.   PLoS Genetics

Anti-Tissue Antibodies Are Related to Lung Function in Chronic Obstructive Pulmonary Disease

(2010) Belén Núñez et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects

(2010) Kai Wang et al.   HUMAN MOLECULAR GENETICS

Genome-wide meta-analyses identify multiple loci associated with smoking behavior

(2010)   NATURE GENETICS

Variants in FAM13A are associated with chronic obstructive pulmonary disease

(2010) Michael H Cho et al.   NATURE GENETICS

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Multiple Independent Loci at Chromosome 15q25.1 Affect Smoking Quantity: a Meta-Analysis and Comparison with Lung Cancer and COPD

(2010) Nancy L. Saccone et al.   PLoS Genetics

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Genome-wide association study identifies five loci associated with lung function

(2009) Emmanouela Repapi et al.   NATURE GENETICS

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function

(2009) Dana B Hancock et al.   NATURE GENETICS

Common variants at five new loci associated with early-onset inflammatory bowel disease

(2009) Marcin Imielinski et al.   NATURE GENETICS

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

(2009) Jeffrey C Barrett et al.   NATURE GENETICS

Alpha1-Antitrypsin Deficiency

(2009) Edwin K. Silverman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Immunologic Aspects of Chronic Obstructive Pulmonary Disease

(2009) Manuel G. Cosio et al.   NEW ENGLAND JOURNAL OF MEDICINE

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Genome-Wide Association Study of Pulmonary Function Measures in the Framingham Heart Study

(2009) Jemma B. Wilk et al.   PLoS Genetics

A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci

(2009) Sreekumar G. Pillai et al.   PLoS Genetics

The Many “Small COPDs”

(2008) Stephen I. Rennard et al.   CHEST

Association of Interleukin (IL)-12 and IL-27 Gene Polymorphisms with Chronic Obstructive Pulmonary Disease in a Chinese Population

(2008) Na Huang et al.   DNA AND CELL BIOLOGY

Structural Basis for Pattern Recognition by the Receptor for Advanced Glycation End Products (RAGE)

(2008) Jingjing Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Risk of Both Ulcerative Colitis and Crohn’s Disease in a Population Suffering from COPD

(2008) Anders Ekbom et al.   LUNG