Recurrent noncoding regulatory mutations in pancreatic ductal adenocarcinoma

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Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer

(2016) Akihiro Fujimoto et al.   NATURE GENETICS

MiR-132, miR-15a and miR-16 synergistically inhibit pituitary tumor cell proliferation, invasion and migration by targeting Sox5

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RUNX3 Controls a Metastatic Switch in Pancreatic Ductal Adenocarcinoma

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Whole genomes redefine the mutational landscape of pancreatic cancer

(2015) Nicola Waddell et al.   NATURE

Identification of significantly mutated regions across cancer types highlights a rich landscape of functional molecular alterations

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Recurrent somatic mutations in regulatory regions of human cancer genomes

(2015) Collin Melton et al.   NATURE GENETICS

The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer

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Cis-regulatory somatic mutations and gene-expression alteration in B-cell lymphomas

(2015) Anthony Mathelier et al.   GENOME BIOLOGY

Determination and Inference of Eukaryotic Transcription Factor Sequence Specificity

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Genome-Wide Investigation of Regional Blood-Based DNA Methylation Adjusted for Complete Blood Counts Implicates BNC2 in Ovarian Cancer

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Genome-wide analysis of noncoding regulatory mutations in cancer

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Systematic analysis of noncoding somatic mutations and gene expression alterations across 14 tumor types

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An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element

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The Tumor Suppressor Ikaros Shapes the Repertoire of Notch Target Genes in T Cells

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HOXB7 mRNA is overexpressed in pancreatic ductal adenocarcinomas and its knockdown induces cell cycle arrest and apoptosis

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Cancer statistics, 2013

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Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity

(2013) Austin M Dulak et al.   NATURE GENETICS

WASF3 regulates miR-200 inactivation by ZEB1 through suppression of KISS1 leading to increased invasiveness in breast cancer cells

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The role of KCNQ1 in mouse and human gastrointestinal cancers

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FoxQ1 Promotes Glioma Cells Proliferation and Migration by Regulating NRXN3 Expression

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TERT promoter mutations in bladder cancer affect patient survival and disease recurrence through modification by a common polymorphism

(2013) P. S. Rachakonda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

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TERT Promoter Mutations in Familial and Sporadic Melanoma

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Highly Recurrent TERT Promoter Mutations in Human Melanoma

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Integrative Annotation of Variants from 1092 Humans: Application to Cancer Genomics

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Gastric inhibitory polypeptide receptor (GIPR) is a promising target for imaging and therapy in neuroendocrine tumors

(2013) Scott K. Sherman et al.   SURGERY

Targeting phosphodiesterase 3B enhances cisplatin sensitivity in human cancer cells

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The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells

(2012) T. Gutschner et al.   CANCER RESEARCH

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

(2012) Andrew V. Biankin et al.   NATURE

An integrated encyclopedia of DNA elements in the human genome

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Bone morphogenetic protein 7: A broad-spectrum growth factor with multiple target therapeutic potency

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Lhx6 and Lhx8 Coordinately Induce Neuronal Expression of Shh that Controls the Generation of Interneuron Progenitors

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Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer

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PAX6 Is Expressed in Pancreatic Cancer and Actively Participates in Cancer Progression through Activation of the MET Tyrosine Kinase Receptor Gene

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CpG methylation analysis of the MEG3 and SNRPN imprinted genes in acute myeloid leukemia and myelodysplastic syndromes

(2009) Leonidas Benetatos et al.   LEUKEMIA RESEARCH

MicroRNA-21 modulates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistance

(2009) T. Moriyama et al.   MOLECULAR CANCER THERAPEUTICS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

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Identification of a panel of sensitive and specific DNA methylation markers for squamous cell lung cancer

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Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

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