G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells

Defining the consequences of genetic variation on a proteome-wide scale

(2016) Joel M. Chick et al.   NATURE

Concise Review: Control of Cell Fate Through Cell Cycle and Pluripotency Networks

(2016) Ben Boward et al.   STEM CELLS

Cyclin-dependent Kinase-mediated Sox2 Phosphorylation Enhances the Ability of Sox2 to Establish the Pluripotent State

(2015) Juan Ouyang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quiescent Sox2+ Cells Drive Hierarchical Growth and Relapse in Sonic Hedgehog Subgroup Medulloblastoma

(2014) Robert J. Vanner et al.   CANCER CELL

Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells

(2014) Mario L. Suvà et al.   CELL

Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis

(2014) Alban Ordureau et al.   MOLECULAR CELL

SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma

(2014) Soufiane Boumahdi et al.   NATURE

Cyclin C is a haploinsufficient tumour suppressor

(2014) Na Li et al.   NATURE CELL BIOLOGY

DNMT-dependent suppression of microRNA regulates the induction of GBM tumor-propagating phenotype by Oct4 and Sox2

(2014) H Lopez-Bertoni et al.   ONCOGENE

Prominin-1 (CD133) Defines Both Stem and Non-Stem Cell Populations in CNS Development and Gliomas

(2014) Karl Holmberg Olausson et al.   PLoS One

Defining an essential transcription factor program for naive pluripotency

(2014) S.- J. Dunn et al.   SCIENCE

Cyclin-dependent kinases

(2014) Marcos Malumbres   GENOME BIOLOGY

The Cell-Cycle State of Stem Cells Determines Cell Fate Propensity

(2013) Siim Pauklin et al.   CELL

The multiple roles for Sox2 in stem cell maintenance and tumorigenesis

(2013) Kuancan Liu et al.   CELLULAR SIGNALLING

Esrrb Is a Pivotal Target of the Gsk3/Tcf3 Axis Regulating Embryonic Stem Cell Self-Renewal

(2012) Graziano Martello et al.   Cell Stem Cell

Cyclin E Constrains Cdk5 Activity to Regulate Synaptic Plasticity and Memory Formation

(2011) Junko Odajima et al.   DEVELOPMENTAL CELL

A Distinct Role for Pin1 in the Induction and Maintenance of Pluripotency

(2011) Mayuko Nishi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24– stem cell–like breast cancer cells in human tumors

(2011) Lauren L.C. Marotta et al.   JOURNAL OF CLINICAL INVESTIGATION

Chemical Genetic Screen for AMPKα2 Substrates Uncovers a Network of Proteins Involved in Mitosis

(2011) Max R. Banko et al.   MOLECULAR CELL

Identification of a SOX2-dependent subset of tumor- and sphere-forming glioblastoma cells with a distinct tyrosine kinase inhibitor sensitivity profile

(2011) Daniel Hägerstrand et al.   NEURO-ONCOLOGY

Activation of Neural and Pluripotent Stem Cell Signatures Correlates with Increased Malignancy in Human Glioma

(2011) Johan Holmberg et al.   PLoS One

Genetic and Epigenetic Modifications of Sox2 Contribute to the Invasive Phenotype of Malignant Gliomas

(2011) Marta M. Alonso et al.   PLoS One

PEST Motif Sequence Regulating Human NANOG for Proteasomal Degradation

(2011) Suresh Ramakrishna et al.   STEM CELLS AND DEVELOPMENT

A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression

(2010) Edward L. Huttlin et al.   CELL

A High Proliferation Rate Is Required for Cell Reprogramming and Maintenance of Human Embryonic Stem Cell Identity

(2010) Sergio Ruiz et al.   CURRENT BIOLOGY

Phosphorylation stabilizes Nanog by promoting its interaction with Pin1

(2010) M. Moretto-Zita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WWP2 promotes degradation of transcription factor OCT4 in human embryonic stem cells

(2009) Huiming Xu et al.   CELL RESEARCH

Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse

(2009) J. Rossant et al.   DEVELOPMENT

Acetylation of Sox2 Induces its Nuclear Export in Embryonic Stem Cells

(2009) Gretchen A. Baltus et al.   STEM CELLS

The ground state of embryonic stem cell self-renewal

(2008) Qi-Long Ying et al.   NATURE

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

(2008) Ittai Ben-Porath et al.   NATURE GENETICS

Expression and functional analysis of G1 to S regulatory components reveals an important role for CDK2 in cell cycle regulation in human embryonic stem cells

(2008) I Neganova et al.   ONCOGENE

SOX2Silencing in Glioblastoma Tumor-Initiating Cells Causes Stop of Proliferation and Loss of Tumorigenicity

(2008) Rosaria Maria Rita Gangemi et al.   STEM CELLS

Cdx2 acts downstream of cell polarization to cell-autonomously promote trophectoderm fate in the early mouse embryo

(2007) Amy Ralston et al.   DEVELOPMENTAL BIOLOGY