cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein–DNA ladders
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein–DNA ladders
Authors
Keywords
-
Journal
NATURE
Volume 549, Issue 7672, Pages 394-398
Publisher
Springer Nature
Online
2017-09-13
DOI
10.1038/nature23890
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP
- (2017) K. L. Jønsson et al. Nature Communications
- Filament assemblies in foreign nucleic acid sensors
- (2016) Jungsan Sohn et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Human Monocytes Engage an Alternative Inflammasome Pathway
- (2016) Moritz M. Gaidt et al. IMMUNITY
- Type I interferon–mediated monogenic autoinflammation: The type I interferonopathies, a conceptual overview
- (2016) Mathieu P. Rodero et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Regulation and function of the cGAS–STING pathway of cytosolic DNA sensing
- (2016) Qi Chen et al. NATURE IMMUNOLOGY
- Sensing of HSV-1 by the cGAS–STING pathway in microglia orchestrates antiviral defence in the CNS
- (2016) Line S. Reinert et al. Nature Communications
- PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1
- (2015) Sunnie M. Yoh et al. CELL
- The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy
- (2015) Robert O. Watson et al. Cell Host & Microbe
- Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1
- (2015) Ruth Wassermann et al. Cell Host & Microbe
- Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis
- (2015) Angela C. Collins et al. Cell Host & Microbe
- Mitochondrial DNA stress primes the antiviral innate immune response
- (2015) A. Phillip West et al. NATURE
- Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA
- (2015) Anna-Maria Herzner et al. NATURE IMMUNOLOGY
- Synthesis of an arrayed sgRNA library targeting the human genome
- (2015) Tobias Schmidt et al. Scientific Reports
- ATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA
- (2015) Charlotte Lässig et al. eLife
- Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production
- (2014) Michael J. White et al. CELL
- Apoptotic Caspases Prevent the Induction of Type I Interferons by Mitochondrial DNA
- (2014) Anthony Rongvaux et al. CELL
- Listeria monocytogenes induces IFN expression through an IFI16-, cGAS- and STING-dependent pathway
- (2014) K. Hansen et al. EMBO JOURNAL
- OutKnocker: a web tool for rapid and simple genotyping of designer nuclease edited cell lines
- (2014) Jonathan L. Schmid-Burgk et al. GENOME RESEARCH
- The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop
- (2014) Xu Zhang et al. Cell Reports
- Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase
- (2013) Pu Gao et al. CELL
- Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization
- (2013) Xin Li et al. IMMUNITY
- Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING
- (2013) Xu Zhang et al. MOLECULAR CELL
- Structural mechanism of cytosolic DNA sensing by cGAS
- (2013) Filiz Civril et al. NATURE
- Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP
- (2013) Andrea Ablasser et al. NATURE
- Cyclic GMP-AMP Synthase Is an Innate Immune Sensor of HIV and Other Retroviruses
- (2013) D. Gao et al. SCIENCE
- C/EBPα Induces Highly Efficient Macrophage Transdifferentiation of B Lymphoma and Leukemia Cell Lines and Impairs Their Tumorigenicity
- (2013) Francesca Rapino et al. Cell Reports
- Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING
- (2012) Christian K Holm et al. NATURE IMMUNOLOGY
- Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
- (2012) L. Sun et al. SCIENCE
- REFMAC5 for the refinement of macromolecular crystal structures
- (2011) Garib N. Murshudov et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Human mitochondrial transcription factor A induces a U-turn structure in the light strand promoter
- (2011) Anna Rubio-Cosials et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The mitochondrial transcription and packaging factor Tfam imposes a U-turn on mitochondrial DNA
- (2011) Huu B Ngo et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Jalview Version 2--a multiple sequence alignment editor and analysis workbench
- (2009) A. M. Waterhouse et al. BIOINFORMATICS
- HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses
- (2009) Hideyuki Yanai et al. NATURE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now