Nanoformulated natural therapeutics for management of streptozotocin-induced diabetes: potential use of curcumin nanoformulation

A newly developed silymarin nanoformulation as a potential antidiabetic agent in experimental diabetes

(2016) Yousra M El-Far et al.   Nanomedicine

Diabetes mellitus and oxidative stress—A concise review

(2016) Ullah Asmat et al.   SAUDI PHARMACEUTICAL JOURNAL

Curcumin enhances recovery of pancreatic islets from cellular stress induced inflammation and apoptosis in diabetic rats

(2015) Kahkashan Rashid et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Recent advances in curcumin nanoformulation for cancer therapy

(2014) Wing-Hin Lee et al.   Expert Opinion on Drug Delivery

Silymarin Induces Expression of Pancreatic Nkx6.1 Transcription Factor and β-Cells Neogenesis in a Pancreatectomy Model

(2014) Claudia Soto et al.   MOLECULES

Engineered Silybin Nanoparticles Educe Efficient Control in Experimental Diabetes

(2014) Suvadra Das et al.   PLoS One

Nkx6.1 regulates islet  -cell proliferation via Nr4a1 and Nr4a3 nuclear receptors

(2014) J. S. Tessem et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of a novel curcumin derivative on insulin synthesis and secretion in streptozotocin-treated rat pancreatic islets in vitro

(2014) Mohammed Talaat Aziz et al.   Chinese Medicine

Reduction of lns-1 gene expression and tissue insulin levels in n5-STZ rats

(2013) Belinda Vargas Guerrero et al.   BIOLOGICAL RESEARCH

Insulin-Producing Cells from Adult Human Bone Marrow Mesenchymal Stem Cells Control Streptozotocin-Induced Diabetes in Nude Mice

(2013) Mahmoud M. Gabr et al.   CELL TRANSPLANTATION

Global gene expression profiling of pancreatic islets in mice during streptozotocin-induced  -cell damage and pancreatic Glp-1 gene therapy

(2013) J. M. Tonne et al.   Disease Models & Mechanisms

Curcumin improves expression of ghrelin through attenuating oxidative stress in gastric tissues of streptozotocin-induced diabetic gastroparesis rats

(2013) Luo Xu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Pdx-1 Activates Islet  - and  -Cell Proliferation via a Mechanism Regulated by Transient Receptor Potential Cation Channels 3 and 6 and Extracellular Signal-Regulated Kinases 1 and 2

(2013) H. L. Hayes et al.   MOLECULAR AND CELLULAR BIOLOGY

Effect of Silymarin in Pdx-1 expression and the proliferation of pancreatic β-cells in a pancreatectomy model

(2013) C. Soto et al.   PHYTOMEDICINE

Apoptosis rate and transcriptional response of pancreatic islets exposed to the PPAR gamma agonist Pioglitazone

(2013) Rodrigo N Lamounier et al.   Diabetology & Metabolic Syndrome

Signaling mechanisms of a water soluble curcumin derivative in experimental type 1 diabetes with cardiomyopathy

(2013) Mohamed Talaat Abdel Aziz et al.   Diabetology & Metabolic Syndrome

Epidermal Growth Factor and Gastrin on PDX1 Expression in Experimental Type 1 Diabetic Rats

(2012) Haiying Yu et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

The use of animal models in diabetes research

(2012) Aileen JF King   BRITISH JOURNAL OF PHARMACOLOGY

Dose-dependent effect in the inhibition of oxidative stress and anticlastogenic potential of ginger in STZ induced diabetic rats

(2012) Nirmala Kota et al.   FOOD CHEMISTRY

Anti-diabetic effect of Wen-pi-tang-Hab-Wu-ling-san extract in streptozotocin-induced diabetic rats

(2012) Yong-Ki Park et al.   INDIAN JOURNAL OF PHARMACOLOGY

Silymarin regulates the cytochrome P450 3A2 and glutathione peroxides in the liver of streptozotocin-induced diabetic rats

(2012) H. Malekinejad et al.   PHYTOMEDICINE

Regeneration of Pancreatic Non-β Endocrine Cells in Adult Mice following a Single Diabetes-Inducing Dose of Streptozotocin

(2012) Yanqing Zhang et al.   PLoS One

Novel role of curcumin combined with bone marrow transplantation in reversing experimental diabetes: Effects on pancreatic islet regeneration, oxidative stress, and inflammatory cytokines

(2011) Mona F. El-Azab et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The antihyperglycemic effect of curcumin in high fat diet fed rats. Role of TNF-α and free fatty acids

(2011) Mohamed A. El-Moselhy et al.   FOOD AND CHEMICAL TOXICOLOGY

Curcumin: An Anti-Inflammatory Molecule from a Curry Spice on the Path to Cancer Treatment

(2011) Purusotam Basnet et al.   MOLECULES

Intracellular ROS Protection Efficiency and Free Radical-Scavenging Activity of Curcumin

(2011) Abolfazl Barzegar et al.   PLoS One

d-saccharic acid-1,4-lactone ameliorates alloxan-induced diabetes mellitus and oxidative stress in rats through inhibiting pancreatic beta-cells from apoptosis via mitochondrial dependent pathway

(2011) Semantee Bhattacharya et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Protective effects of nanoparticulate coenzyme Q10 and curcumin on inflammatory markers and lipid metabolism in streptozotocin-induced diabetic rats: a possible remedy to diabetic complications

(2011) Venkat Ratnam Devadasu et al.   Drug Delivery and Translational Research

Glutathione Peroxidase-1 in Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities

(2010) Edith Lubos et al.   ANTIOXIDANTS & REDOX SIGNALING

Curcumin suppresses the dynamic instability of microtubules, activates the mitotic checkpoint and induces apoptosis in MCF-7 cells

(2010) Mithu Banerjee et al.   FEBS Journal

Effect of Experimental Diabetes and STZ on Male Fertility Capacity. Study in Rats

(2010) L. Navarro-Casado et al.   JOURNAL OF ANDROLOGY

Curcumin and obesity: evidence and mechanisms

(2010) Lini Alappat et al.   NUTRITION REVIEWS

Pdx1 and other factors that regulate pancreatic β-cell survival

(2009) K. Fujimoto et al.   DIABETES OBESITY & METABOLISM

Curcumin prevents diabetes-associated abnormalities in the kidneys by inhibiting p300 and nuclear factor-κB

(2009) Jane Chiu et al.   NUTRITION

Novel role of curcumin in the prevention of cytokine-induced islet death in vitro and diabetogenesis in vivo

(2008) M Kanitkar et al.   BRITISH JOURNAL OF PHARMACOLOGY

Antioxidant and radical scavenging properties of curcumin

(2008) Tuba Ak et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Dietary Curcumin Significantly Improves Obesity-Associated Inflammation and Diabetes in Mouse Models of Diabesity

(2008) Stuart P. Weisberg et al.   ENDOCRINOLOGY

Stimulation of Human and Rat Islet  -Cell Proliferation with Retention of Function by the Homeodomain Transcription Factor Nkx6.1

(2008) J. C. Schisler et al.   MOLECULAR AND CELLULAR BIOLOGY