Rational Design of Nucleoside–Bile Acid Conjugates Incorporating a Triazole Moiety for Anticancer Evaluation and SAR Exploration

1,2,3-Triazolyl ester of Ketorolac: A “Click Chemistry”-based highly potent PAK1-blocking cancer-killer

(2017) Binh Cao Quan Nguyen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Fluorous-tag assisted synthesis of bile acid–bisphosphonate conjugates via orthogonal click reactions: an access to potential anti-resorption bone drugs

(2017) Chiara Massarenti et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

NO Photoreleaser-Deoxyadenosine and -Bile Acid Derivative Bioconjugates as Novel Potential Photochemotherapeutics

(2016) Maria Luisa Navacchia et al.   ACS Medicinal Chemistry Letters

Design and strategies for bile acid mediated therapy and imaging

(2016) Md Nurunnabi et al.   RSC Advances

Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters

(2014) Zachary Lee Johnson et al.   eLife

Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases

(2013) Lars Petter Jordheim et al.   NATURE REVIEWS DRUG DISCOVERY

Synthesis and in vitro cytotoxicity of deoxyadenosine–bile acid conjugates linked with 1,2,3-triazole

(2013) Daniela Perrone et al.   NEW JOURNAL OF CHEMISTRY

Zidovudine and Ursodeoxycholic Acid Conjugation: Design of a New Prodrug Potentially Able To Bypass the Active Efflux Transport Systems of the Central Nervous System

(2012) Alessandro Dalpiaz et al.   MOLECULAR PHARMACEUTICS

Metal-Free Efficient, General and Facile Iododecarboxylation Method with Biodegradable Co-Products

(2011) Kseniya Kulbitski et al.   ADVANCED SYNTHESIS & CATALYSIS

Transporters, Trojan horses and therapeutics: suitability of bile acid and peptide transporters for drug delivery

(2011) Werner Kramer   BIOLOGICAL CHEMISTRY

Bile acids and colon cancer: Solving the puzzle with nuclear receptors

(2011) Chiara Degirolamo et al.   TRENDS IN MOLECULAR MEDICINE

Natural compounds for cancer treatment and prevention

(2009) Stefania Nobili et al.   PHARMACOLOGICAL RESEARCH

Bile Acids: Chemistry, Pathochemistry, Biology, Pathobiology, and Therapeutics

(2008) A. F. Hofmann et al.   CELLULAR AND MOLECULAR LIFE SCIENCES