Synaptic activity protects against AD and FTD-like pathology via autophagic-lysosomal degradation
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Synaptic activity protects against AD and FTD-like pathology via autophagic-lysosomal degradation
Authors
Keywords
-
Journal
MOLECULAR PSYCHIATRY
Volume 23, Issue 6, Pages 1530-1540
Publisher
Springer Nature
Online
2017-07-11
DOI
10.1038/mp.2017.142
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities
- (2017) Fiona M. Menzies et al. NEURON
- Evidence that Non-Fibrillar Tau Causes Pathology Linked to Neurodegeneration and Behavioral Impairments
- (2017) Kurt R. Brunden et al. JOURNAL OF ALZHEIMERS DISEASE
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
- (2016) Daniel J Klionsky et al. Autophagy
- Lysosomal dysfunction disrupts presynaptic maintenance and restoration of presynaptic function prevents neurodegeneration in lysosomal storage diseases
- (2016) Irene Sambri et al. EMBO Molecular Medicine
- A Phase II Study of Fornix Deep Brain Stimulation in Mild Alzheimer’s Disease
- (2016) Andres M. Lozano et al. JOURNAL OF ALZHEIMERS DISEASE
- Bilateral deep brain stimulation of the fornix for Alzheimer's disease: surgical safety in the ADvance trial
- (2016) Francisco A. Ponce et al. JOURNAL OF NEUROSURGERY
- Memory retrieval by activating engram cells in mouse models of early Alzheimer’s disease
- (2016) Dheeraj S. Roy et al. NATURE
- Neuronal activity enhances tau propagation and tau pathology in vivo
- (2016) Jessica W Wu et al. NATURE NEUROSCIENCE
- Deep Brain Stimulation Influences Brain Structure in Alzheimer's Disease
- (2015) Tejas Sankar et al. Brain Stimulation
- Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB
- (2015) Diego L. Medina et al. NATURE CELL BIOLOGY
- The storm before the quiet: neuronal hyperactivity and Aβ in the presymptomatic stages of Alzheimer's disease
- (2015) Anita Stargardt et al. NEUROBIOLOGY OF AGING
- Eating Locally: Microautophagy and Protein Turnover at the Synapse
- (2015) Peter S. McPherson NEURON
- Hsc70-4 Deforms Membranes to Promote Synaptic Protein Turnover by Endosomal Microautophagy
- (2015) Valerie Uytterhoeven et al. NEURON
- Synaptic activity and Alzheimer's disease: a critical update
- (2015) Davide Tampellini Frontiers in Neuroscience
- Rapamycin protects against Aβ-induced synaptotoxicity by increasing presynaptic activity in hippocampal neurons
- (2014) A.E. Ramírez et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Activity-Driven Local ATP Synthesis Is Required for Synaptic Function
- (2014) Vidhya Rangaraju et al. CELL
- Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB
- (2014) V. A. Polito et al. EMBO Molecular Medicine
- Neuronal activity regulates extracellular tau in vivo
- (2014) Kaoru Yamada et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Activity-Dependent Tau Protein Translocation to Excitatory Synapse Is Disrupted by Exposure to Amyloid-Beta Oligomers
- (2014) M. L. Frandemiche et al. JOURNAL OF NEUROSCIENCE
- Neural compensation in older people with brain amyloid-β deposition
- (2014) Jeremy A Elman et al. NATURE NEUROSCIENCE
- Physical exercise improves synaptic dysfunction and recovers the loss of survival factors in 3xTg-AD mouse brain
- (2014) Susana Revilla et al. NEUROPHARMACOLOGY
- Role of Endosomes and Lysosomes in Human Disease
- (2014) F. R. Maxfield Cold Spring Harbor Perspectives in Biology
- Physiological release of endogenous tau is stimulated by neuronal activity
- (2013) Amy M Pooler et al. EMBO REPORTS
- Tau degradation: The ubiquitin–proteasome system versus the autophagy-lysosome system
- (2013) Min Jae Lee et al. PROGRESS IN NEUROBIOLOGY
- The Ubiquitin-Proteasome System and the Autophagic-Lysosomal System in Alzheimer Disease
- (2013) Y. Ihara et al. Cold Spring Harbor Perspectives in Medicine
- Tau Clearance Mechanisms and Their Possible Role in the Pathogenesis of Alzheimer Disease
- (2013) Adrianne S. Chesser et al. Frontiers in Neurology
- The Synaptic Accumulation of Hyperphosphorylated Tau Oligomers in Alzheimer Disease Is Associated With Dysfunction of the Ubiquitin-Proteasome System
- (2012) Hwan-Ching Tai et al. AMERICAN JOURNAL OF PATHOLOGY
- Increased Cerebral Metabolism After 1 Year of Deep Brain Stimulation in Alzheimer Disease
- (2012) Gwenn S. Smith et al. ARCHIVES OF NEUROLOGY
- Stimulation of autophagy is neuroprotective in a mouse model of human tauopathy
- (2012) Véronique Schaeffer et al. Autophagy
- Stimulation of autophagy reduces neurodegeneration in a mouse model of human tauopathy
- (2012) Véronique Schaeffer et al. BRAIN
- Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons
- (2012) Sandra Maday et al. JOURNAL OF CELL BIOLOGY
- The divergence–convergence model of acquired neuroprotection
- (2012) Carlos Bas-Orth et al. MECHANISMS OF DEVELOPMENT
- p62 Stages an Interplay Between the Ubiquitin-Proteasome System and Autophagy in the Heart of Defense Against Proteotoxic Stress
- (2012) Huabo Su et al. TRENDS IN CARDIOVASCULAR MEDICINE
- Transcriptional Activation of Lysosomal Exocytosis Promotes Cellular Clearance
- (2011) Diego L. Medina et al. DEVELOPMENTAL CELL
- Impaired -Amyloid Secretion in Alzheimer's Disease Pathogenesis
- (2011) D. Tampellini et al. JOURNAL OF NEUROSCIENCE
- Stimulation of Entorhinal Cortex Promotes Adult Neurogenesis and Facilitates Spatial Memory
- (2011) S. S. D. Stone et al. JOURNAL OF NEUROSCIENCE
- Autophagy failure in Alzheimer's disease—locating the primary defect
- (2011) Ralph A. Nixon et al. NEUROBIOLOGY OF DISEASE
- Hippocampal synaptic plasticity in Alzheimer’s disease: what have we learned so far from transgenic models?
- (2011) Cristina Marchetti et al. REVIEWS IN THE NEUROSCIENCES
- Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer’s disease
- (2010) Gunnar K. Gouras et al. ACTA NEUROPATHOLOGICA
- A phase I trial of deep brain stimulation of memory circuits in Alzheimer's disease
- (2010) Adrian W. Laxton et al. ANNALS OF NEUROLOGY
- (Re-)activation of neurons in aging and dementia: Lessons from the hypothalamus
- (2010) Dick F. Swaab et al. EXPERIMENTAL GERONTOLOGY
- Molecular Interplay between Mammalian Target of Rapamycin (mTOR), Amyloid-β, and Tau
- (2010) Antonella Caccamo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Effects of Synaptic Modulation on -Amyloid, Synaptophysin, and Memory Performance in Alzheimer's Disease Transgenic Mice
- (2010) D. Tampellini et al. JOURNAL OF NEUROSCIENCE
- Synapse loss in dementias
- (2010) Ryan Clare et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Longitudinal fMRI in elderly reveals loss of hippocampal activation with clinical decline
- (2010) J. L. O'Brien et al. NEUROLOGY
- Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing
- (2009) Yipeng Wang et al. HUMAN MOLECULAR GENETICS
- Synaptic Activity Reduces Intraneuronal A , Promotes APP Transport to Synapses, and Protects against A -Related Synaptic Alterations
- (2009) D. Tampellini et al. JOURNAL OF NEUROSCIENCE
- Amyloid Deposition Is Associated with Impaired Default Network Function in Older Persons without Dementia
- (2009) Reisa A. Sperling et al. NEURON
- Autophagic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression
- (2008) Tadanori Hamano et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Genetic inactivation of p62 leads to accumulation of hyperphosphorylated tau and neurodegeneration
- (2008) J. Ramesh Babu et al. JOURNAL OF NEUROCHEMISTRY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now