Characterisation of Nav1.7 functional expression in rat dorsal root ganglia neurons by using an electrical field stimulation assay

Insensitivity to pain induced by a potent selective closed-state Nav1.7 inhibitor

(2017) M. Flinspach et al.   Scientific Reports

The structure, dynamics and selectivity profile of a NaV1.7 potency-optimised huwentoxin-IV variant

(2017) Sassan Rahnama et al.   PLoS One

Nav1.7 and other voltage-gated sodium channels as drug targets for pain relief

(2016) Edward C Emery et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia

(2016) Lishuang Cao et al.   Science Translational Medicine

Analgesic Effects of GpTx-1, PF-04856264 and CNV1014802 in a Mouse Model of NaV1.7-Mediated Pain

(2016) Jennifer Deuis et al.   Toxins

Voltage gated sodium channels as drug discovery targets

(2015) Sharan K Bagal et al.   Channels

Voltage-Gated Sodium Channels: Structure, Function, Pharmacology, and Clinical Indications

(2015) Manuel de Lera Ruiz et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Small-Molecule Photoactivatable Optical Sensor of Transmembrane Potential

(2015) Vincent Grenier et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Primary erythromelalgia: a review

(2015) Zhaoli Tang et al.   Orphanet Journal of Rare Diseases

The Specification and Maturation of Nociceptive Neurons from Human Embryonic Stem Cells

(2015) Erin M. Boisvert et al.   Scientific Reports

No Gain, No Pain: NaV1.7 as an Analgesic Target

(2014) Glenn F. King et al.   ACS Chemical Neuroscience

Characterizing Human Stem Cell–derived Sensory Neurons at the Single-cell Level Reveals Their Ion Channel Expression and Utility in Pain Research

(2014) Gareth T Young et al.   MOLECULAR THERAPY

Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts

(2014) Brian J Wainger et al.   NATURE NEUROSCIENCE

High-fidelity optical reporting of neuronal electrical activity with an ultrafast fluorescent voltage sensor

(2014) François St-Pierre et al.   NATURE NEUROSCIENCE

Pharmacological characterisation of ligand- and voltage-gated ion channels expressed in human iPSC-derived forebrain neurons

(2014) Jeffrey L. Dage et al.   PSYCHOPHARMACOLOGY

Contrasting Properties of α7-Selective Orthosteric and Allosteric Agonists Examined on Native Nicotinic Acetylcholine Receptors

(2013) JasKiran K. Gill et al.   PLoS One

Voltage-gated sodium channels at 60: structure, function and pathophysiology

(2012) William A. Catterall   JOURNAL OF PHYSIOLOGY-LONDON

Optical recording of action potentials in mammalian neurons using a microbial rhodopsin

(2011) Joel M Kralj et al.   NATURE METHODS

Comparative study of voltage-gated sodium channel α-subunits in non-overlapping four neuronal populations in the rat dorsal root ganglion

(2011) Tetsuo Fukuoka et al.   NEUROSCIENCE RESEARCH

Calcium-dependent inhibition of T-type calcium channels by TRPV1 activation in rat sensory neurons

(2011) Valentina Comunanza et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Pungency of TRPV1 agonists is directly correlated with kinetics of receptor activation and lipophilicity

(2010) Daniel Ursu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Single-cell analysis of sodium channel expression in dorsal root ganglion neurons

(2010) Cojen Ho et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

NaV1.7 Gain-of-Function Mutations as a Continuum: A1632E Displays Physiological Changes Associated with Erythromelalgia and Paroxysmal Extreme Pain Disorder Mutations and Produces Symptoms of Both Disorders

(2008) M. Estacion et al.   JOURNAL OF NEUROSCIENCE

Paroxysmal extreme pain disorder mutations within the D3/S4-S5 linker of Nav1.7 cause moderate destabilization of fast inactivation

(2008) Brian W. Jarecki et al.   JOURNAL OF PHYSIOLOGY-LONDON

ProTx-II, a Selective Inhibitor of NaV1.7 Sodium Channels, Blocks Action Potential Propagation in Nociceptors

(2008) W. A. Schmalhofer et al.   MOLECULAR PHARMACOLOGY