Toll-Like Receptor 2-Mediated Glial Cell Activation in a Mouse Model of Cuprizone-Induced Demyelination

Combination of cuprizone and experimental autoimmune encephalomyelitis to study inflammatory brain lesion formation and progression

(2017) Bernhard Josef Rüther et al.   GLIA

Formyl Peptide Receptor 1-Mediated Glial Cell Activation in a Mouse Model of Cuprizone-Induced Demyelination

(2017) Kai Bihler et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Cuprizone-Containing Pellets Are Less Potent to Induce Consistent Demyelination in the Corpus Callosum of C57BL/6 Mice

(2017) Tanja Hochstrasser et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Innate immune regulation of autoimmunity in multiple sclerosis: Focus on the role of Toll-like receptor 2

(2017) Md Jakir Hossain et al.   JOURNAL OF NEUROIMMUNOLOGY

Effect of Intrastriatal 6-OHDA Lesions on Extrastriatal Brain Structures in the Mouse

(2017) Birte Becker et al.   MOLECULAR NEUROBIOLOGY

Activation of the astrocytic Nrf2/ARE system ameliorates the formation of demyelinating lesions in a multiple sclerosis animal model

(2016) T. Draheim et al.   GLIA

Thalamus Degeneration and Inflammation in Two Distinct Multiple Sclerosis Animal Models

(2016) Nina Wagenknecht et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Lack of Toll-like receptor 2 results in higher mortality of bacterial meningitis by impaired host resistance

(2016) Martin Böhland et al.   JOURNAL OF NEUROIMMUNOLOGY

Neurodegeneration Triggers Peripheral Immune Cell Recruitment into the Forebrain

(2016) M. Scheld et al.   JOURNAL OF NEUROSCIENCE

Lack of Proinflammatory Cytokine Interleukin-6 or Tumor Necrosis Factor Receptor-1 Results in a Failure of the Innate Immune Response after Bacterial Meningitis

(2016) Lea-Jessica Albrecht et al.   MEDIATORS OF INFLAMMATION

Impact of Exercise on Innate Immunity in Multiple Sclerosis Progression and Symptomatology

(2016) Alison Barry et al.   Frontiers in Physiology

High-mobility group box 1 in multiple sclerosis

(2015) Zohara Sternberg et al.   IMMUNOLOGIC RESEARCH

CXCL10 Triggers Early Microglial Activation in the Cuprizone Model

(2015) Tim Clarner et al.   JOURNAL OF IMMUNOLOGY

Anatomical Distribution of Cuprizone-Induced Lesions in C57BL6 Mice

(2015) Johannes Goldberg et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

HMGB1 expression patterns during the progression of experimental autoimmune encephalomyelitis

(2015) Yan Sun et al.   JOURNAL OF NEUROIMMUNOLOGY

Absence of CCL2 and CCL3 Ameliorates Central Nervous System Grey Matter But Not White Matter Demyelination in the Presence of an Intact Blood–Brain Barrier

(2015) Katharina Janssen et al.   MOLECULAR NEUROBIOLOGY

Lesion Expansion in Experimental Demyelination Animal Models and Multiple Sclerosis Lesions

(2015) René Große-Veldmann et al.   MOLECULAR NEUROBIOLOGY

Activation and Regulation of NLRP3 Inflammasome by Intrathecal Application of SDF-1a in a Spinal Cord Injury Model

(2015) Adib Zendedel et al.   MOLECULAR NEUROBIOLOGY

TLR2 – an innate immune checkpoint in multiple sclerosis

(2015) Md Jakir Hossain et al.   Oncotarget

Demyelination during multiple sclerosis is associated with combined activation of microglia/macrophages by IFN-γ and alpha B-crystallin

(2014) Malika Bsibsi et al.   ACTA NEUROPATHOLOGICA

Lack of formyl peptide receptor 1 and 2 leads to more severe inflammation and higher mortality in mice with of pneumococcal meningitis

(2014) Sandra Oldekamp et al.   IMMUNOLOGY

Initial Immunopathogenesis of Multiple Sclerosis: Innate Immune Response

(2013) Norma Y. Hernández-Pedro et al.   Clinical & Developmental Immunology

APC binds intermediate filaments and is required for their reorganization during cell migration

(2013) Yasuhisa Sakamoto et al.   JOURNAL OF CELL BIOLOGY

Cuprizone-Induced Demyelination as a Tool to Study Remyelination and Axonal Protection

(2013) Adib Zendedel et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Astrocytes regulate myelin clearance through recruitment of microglia during cuprizone-induced demyelination

(2012) Thomas Skripuletz et al.   BRAIN

Pathology of Multiple Sclerosis

(2012) Markus Kipp et al.   CNS & Neurological Disorders-Drug Targets

In Vitro and In Vivo Models of Multiple Sclerosis

(2012) Baukje J. van der Star et al.   CNS & Neurological Disorders-Drug Targets

Myelin debris regulates inflammatory responses in an experimental demyelination animal model and multiple sclerosis lesions

(2012) Tim Clarner et al.   GLIA

The innate immune system in demyelinating disease

(2012) Lior Mayo et al.   IMMUNOLOGICAL REVIEWS

Innate immunity in the central nervous system

(2012) Richard M. Ransohoff et al.   JOURNAL OF CLINICAL INVESTIGATION

Inflammatory Response and Chemokine Expression in the White Matter Corpus Callosum and Gray Matter Cortex Region During Cuprizone-Induced Demyelination

(2012) J. P. Buschmann et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

CpG oligodeoxynucleotides induce the expression of the antimicrobial peptide cathelicidin in glial cells

(2012) Lars-Ove Brandenburg et al.   JOURNAL OF NEUROIMMUNOLOGY

Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential

(2011) Mark L. Hanke et al.   CLINICAL SCIENCE

Corticosteroids Impair Remyelination in the Corpus Callosum of Cuprizone-Treated Mice

(2011) T. Clarner et al.   JOURNAL OF NEUROENDOCRINOLOGY

T cells in multiple sclerosis and experimental autoimmune encephalomyelitis

(2010) J. M. Fletcher et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Glial Amyloid Precursor Protein Expression is Restricted to Astrocytes in an Experimental Toxic Model of Multiple Sclerosis

(2010) Tim Clarner et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Hyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2

(2010) J. A. Sloane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cuprizone animal model: new insights into an old story

(2009) Markus Kipp et al.   ACTA NEUROPATHOLOGICA

Preactive lesions in multiple sclerosis

(2009) Paul van der Valk et al.   CURRENT OPINION IN NEUROLOGY

Innate immunity and neuroinflammation in the CNS: The role of microglia in Toll-like receptor-mediated neuronal injury

(2009) Seija Lehnardt   GLIA

Microglia in Infectious Diseases of the Central Nervous System

(2009) Monica M. Mariani et al.   Journal of Neuroimmune Pharmacology

Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE

(2009) Mauricio F Farez et al.   NATURE IMMUNOLOGY

Cortical Demyelination Is Prominent in the Murine Cuprizone Model and Is Strain-Dependent

(2008) Thomas Skripuletz et al.   AMERICAN JOURNAL OF PATHOLOGY

17β-estradiol and progesterone prevent cuprizone provoked demyelination of corpus callosum in male mice

(2008) Peter Acs et al.   GLIA

Pivotal Advance: HMGB1 expression in active lesions of human and experimental multiple sclerosis

(2008) Åsa Andersson et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Brain-Region-Specific Astroglial Responses In Vitro After LPS Exposure

(2008) Markus Kipp et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

MHC class II exacerbates demyelination in vivo independently of T cells

(2008) Meenaxi M. Hiremath et al.   JOURNAL OF NEUROIMMUNOLOGY