Blood-Brain Barrier Permeability Is Exacerbated in Experimental Model of Hepatic Encephalopathy via MMP-9 Activation and Downregulation of Tight Junction Proteins

Role of dopaminergic and serotonergic neurotransmitters in behavioral alterations observed in rodent model of hepatic encephalopathy

(2015) Saurabh Dhanda et al.   BEHAVIOURAL BRAIN RESEARCH

TGFβ1 exacerbates blood–brain barrier permeability in a mouse model of hepatic encephalopathy via upregulation of MMP9 and downregulation of claudin-5

(2015) Matthew A McMillin et al.   LABORATORY INVESTIGATION

Friends or Foes: Matrix Metalloproteinases and Their Multifaceted Roles in Neurodegenerative Diseases

(2015) Marjana Brkic et al.   MEDIATORS OF INFLAMMATION

Aquaporin 9 expression is required for l-lactate to maintain retinal neuronal survival

(2015) Azusa Akashi et al.   NEUROSCIENCE LETTERS

Ethyl acetate fraction of Amomum xanthioides improves bile duct ligation-induced liver fibrosis of rat model via modulation of pro-fibrogenic cytokines

(2015) Hyeong-Geug Kim et al.   Scientific Reports

Bile acids permeabilize the blood brain barrier after bile duct ligation in rats via Rac1-dependent mechanisms

(2014) Matthew Quinn et al.   DIGESTIVE AND LIVER DISEASE

Hepatic encephalopathy in chronic liver disease: 2014 Practice Guideline by the American Association for the Study Of Liver Diseases and the European Association for the Study of the Liver

(2014) Hendrik Vilstrup et al.   HEPATOLOGY

Ammonia, Like K+, Stimulates the Na+, K+, 2 Cl− Cotransporter NKCC1 and the Na+,K+-ATPase and Interacts with Endogenous Ouabain in Astrocytes

(2014) Leif Hertz et al.   NEUROCHEMICAL RESEARCH

Ammonium Increases Ca2+ Signalling and Up-Regulates Expression of TRPC1 Gene in Astrocytes in Primary Cultures and in the In Vivo Brain

(2014) Chunguang Liang et al.   NEUROCHEMICAL RESEARCH

Dysbalance of Astrocyte Calcium under Hyperammonemic Conditions

(2014) Nicole Haack et al.   PLoS One

Synaptic plasticity in hepatic encephalopathy – A molecular perspective

(2013) Shuping Wen et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Expression of astrocytic genes coding for proteins implicated in neural excitation and brain edema is altered after acute liver failure

(2013) Kiran K. Thumburu et al.   JOURNAL OF NEUROCHEMISTRY

Lipopolysaccharide precipitates hepatic encephalopathy and increases blood-brain barrier permeability in mice with acute liver failure

(2013) Anne Chastre et al.   LIVER INTERNATIONAL

Aquaporin-4 deletion in mice reduces encephalopathy and brain edema in experimental acute liver failure

(2013) Kakulavarapu V. Rama Rao et al.   NEUROBIOLOGY OF DISEASE

Brain edema in acute liver failure and chronic liver disease: Similarities and differences

(2013) Cristina R. Bosoi et al.   NEUROCHEMISTRY INTERNATIONAL

Distinct Patterns of Cerebral Extravasation by Evans Blue and Sodium Fluorescein in Rats

(2013) Lola Fenghuei Yen et al.   PLoS One

Systemic oxidative stress is implicated in the pathogenesis of brain edema in rats with chronic liver failure

(2012) Cristina R. Bosoi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Ammonia increases paracellular permeability of rat brain endothelial cells by a mechanism encompassing oxidative/nitrosative stress and activation of matrix metalloproteinases

(2012) Marta Skowrońska et al.   JOURNAL OF NEUROCHEMISTRY

Endothelial-astrocytic interactions in acute liver failure

(2012) A. R. Jayakumar et al.   METABOLIC BRAIN DISEASE

Alterations in NADPH oxidase expression and blood–brain barrier in bile duct ligation-treated young rats: Effects of melatonin

(2012) Yu-Chieh Chen et al.   NEUROCHEMISTRY INTERNATIONAL

Delayed increase of astrocytic aquaporin 4 after juvenile traumatic brain injury: Possible role in edema resolution?

(2012) A.M. Fukuda et al.   NEUROSCIENCE

Occludin dislocation in brain capillary endothelium of rats with bile duct ligation induced cholestasis

(2012) Adamantios G. Mavrakis et al.   NEUROSCIENCE LETTERS

Aquaporins in Cerebrovascular Disease: A Target for Treatment of Brain Edema

(2011) J. Badaut et al.   CEREBROVASCULAR DISEASES

Altered occludin expression in brain capillaries induced by obstructive jaundice in rats

(2010) Konstantinos Faropoulos et al.   BRAIN RESEARCH

Calcium dyshomeostasis and pathological calcium signalling in neurological diseases

(2010) Maiken Nedergaard et al.   CELL CALCIUM

Role of aquaporin-4 in the development of brain oedema in liver failure

(2010) Gavin Wright et al.   JOURNAL OF HEPATOLOGY

Transporters involved in the hepatic uptake of 99mTc-mebrofenin and indocyanine green

(2010) Wilmar de Graaf et al.   JOURNAL OF HEPATOLOGY

Ammonium influx pathways into astrocytes and neurones of hippocampal slices

(2010) Tony Kelly et al.   JOURNAL OF NEUROCHEMISTRY

Tumour necrosis factor-α affects blood-brain barrier permeability and tight junction-associated occludin in acute liver failure

(2010) Sa Lv et al.   LIVER INTERNATIONAL

High and Low Molecular Weight Fluorescein Isothiocyanate (FITC)–Dextrans to Assess Blood-Brain Barrier Disruption: Technical Considerations

(2010) Angelika Hoffmann et al.   Translational Stroke Research

Disruptions of occludin and claudin-5 in brain endothelial cells in vitro and in brains of mice with acute liver failure

(2009) Feng Chen et al.   HEPATOLOGY

Ammonia and the neutrophil in the pathogenesis of hepatic encephalopathy in cirrhosis

(2009) Debbie L. Shawcross et al.   HEPATOLOGY

Reduction of lipoxidative load by secretory phospholipase A2 inhibition protects against neurovascular injury following experimental stroke in rat

(2009) Md Nasrul Hoda et al.   Journal of Neuroinflammation

Matrix metalloproteinases and their multiple roles in neurodegenerative diseases

(2009) Gary A Rosenberg   LANCET NEUROLOGY

Experimental models of hepatic encephalopathy: ISHEN guidelines

(2009) Roger F. Butterworth et al.   LIVER INTERNATIONAL

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

Alterations in expression of genes coding for proteins of the neurovascular unit in ischemic liver failure

(2009) Kei Sawara et al.   NEUROCHEMISTRY INTERNATIONAL

Altered expression and distribution of aquaporin-9 in the liver of rat with obstructive extrahepatic cholestasis

(2008) Giuseppe Calamita et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Characterization of time-related changes after experimental bile duct ligation

(2008) P. Georgiev et al.   BRITISH JOURNAL OF SURGERY

Na-K-Cl Cotransporter-1 in the Mechanism of Ammonia-induced Astrocyte Swelling

(2008) Arumugam R. Jayakumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased blood brain barrier permeability is not a primary determinant for lethality of West Nile virus infection in rodents

(2008) J. D. Morrey et al.   JOURNAL OF GENERAL VIROLOGY

Altered Expression of Zonula Occludens-2 Precedes Increased Blood–Brain Barrier Permeability in a Murine Model of Fulminant Hepatic Failure

(2008) Naoki Shimojima et al.   JOURNAL OF INVESTIGATIVE SURGERY

MMPs in the central nervous system: Where the good guys go bad

(2007) S AGRAWAL et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY