Ammonia, Like K+, Stimulates the Na+, K+, 2 Cl− Cotransporter NKCC1 and the Na+,K+-ATPase and Interacts with Endogenous Ouabain in Astrocytes

Contributions of the Na+/K+-ATPase, NKCC1, and Kir4.1 to hippocampal K+clearance and volume responses

(2014) Brian Roland Larsen et al.   GLIA

Brain edema in acute liver failure: mechanisms and concepts

(2014) Kakulavarapu V. Rama Rao et al.   METABOLIC BRAIN DISEASE

Effects of canrenone in patients with metabolic syndrome

(2013) Giuseppe Derosa et al.   EXPERT OPINION ON PHARMACOTHERAPY

Ammonia triggers neuronal disinhibition and seizures by impairing astrocyte potassium buffering

(2013) Vinita Rangroo Thrane et al.   NATURE MEDICINE

Roles of Changes in Active Glutamine Transport in Brain Edema Development During Hepatic Encephalopathy: An Emerging Concept

(2013) Magdalena Zielińska et al.   NEUROCHEMICAL RESEARCH

Brain edema in acute liver failure and chronic liver disease: Similarities and differences

(2013) Cristina R. Bosoi et al.   NEUROCHEMISTRY INTERNATIONAL

Ammonia-induced Na,K-ATPase/ouabain-mediated EGF receptor transactivation, MAPK/ERK and PI3K/AKT signaling and ROS formation cause astrocyte swelling

(2013) Hongliang Dai et al.   NEUROCHEMISTRY INTERNATIONAL

Disruption of Ion Homeostasis in the Neurogliovascular Unit Underlies the Pathogenesis of Ischemic Cerebral Edema

(2013) Arjun Khanna et al.   Translational Stroke Research

Different roles of the cardiac Na+/Ca2+-exchanger in ouabain-induced inotropy, cell signaling, and hypertrophy

(2012) Yan Bai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cerebral Edema

(2012) Mai-Lan Ho et al.   AMERICAN JOURNAL OF ROENTGENOLOGY

Synergistic stimulation by potassium and ammonium of K+-phosphatase activity in gill microsomes from the crab Callinectes ornatus acclimated to low salinity: Novel property of a primordial pump

(2012) Daniela P. Garçon et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Ammonia-Lowering Strategies for the Treatment of Hepatic Encephalopathy

(2012) C F Rose   CLINICAL PHARMACOLOGY & THERAPEUTICS

Kir4.1 channels mediate a depolarization of hippocampal astrocytes under hyperammonemic conditions in situ

(2012) Jonathan Stephan et al.   GLIA

Cotransport of water by Na+-K+-2Cl−cotransporters expressed inXenopusoocytes: NKCC1versusNKCC2

(2012) Thomas Zeuthen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Decrease of glutathione content in the prefrontal cortical mitochondria of rats with acute hepatic encephalopathy: prevention by histidine

(2012) Joanna Ruszkiewicz et al.   METABOLIC BRAIN DISEASE

Requirement of Glycogenolysis for Uptake of Increased Extracellular K+ in Astrocytes: Potential Implications for K+ Homeostasis and Glycogen Usage in Brain

(2012) Junnan Xu et al.   NEUROCHEMICAL RESEARCH

Patterns of Brain Injury in Inborn Errors of Metabolism

(2012) Andrea L. Gropman   Seminars in Pediatric Neurology

Comparative Properties of Caveolar and Noncaveolar Preparations of Kidney Na+/K+-ATPase

(2011) Lijun Liu et al.   BIOCHEMISTRY

Na-K-Cl cotransporter-1 in the mechanism of cell swelling in cultured astrocytes after fluid percussion injury

(2011) Arumugam R. Jayakumar et al.   JOURNAL OF NEUROCHEMISTRY

Components of neuronal chloride transport in rat and human neocortex

(2011) Rudolf A. Deisz et al.   JOURNAL OF PHYSIOLOGY-LONDON

Ouabain increases iNOS-dependent nitric oxide generation which contributes to the hypertrophic effect of the glycoside: possible role of peroxynitrite formation

(2011) Xiaohong Tracey Gan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Ammonia-induced brain swelling and neurotoxicity in an organotypic slice model

(2011) Adam Back et al.   NEUROLOGICAL RESEARCH

Phosphorylation and Transport in the Na-K-2Cl Cotransporters, NKCC1 and NKCC2A, Compared in HEK-293 Cells

(2011) Anke Hannemann et al.   PLoS One

Bisphenol A and 17β-Estradiol Promote Arrhythmia in the Female Heart via Alteration of Calcium Handling

(2011) Sujuan Yan et al.   PLoS One

Glutamine as a mediator of ammonia neurotoxicity: A critical appraisal

(2010) Jan Albrecht et al.   BIOCHEMICAL PHARMACOLOGY

The Na–K–Cl cotransporter in the brain edema of acute liver failure

(2010) Arumugam R. Jayakumar et al.   JOURNAL OF HEPATOLOGY

Ammonium influx pathways into astrocytes and neurones of hippocampal slices

(2010) Tony Kelly et al.   JOURNAL OF NEUROCHEMISTRY

Cotransport of water by the Na+-K+-2Cl−cotransporter NKCC1 in mammalian epithelial cells

(2010) Steffen Hamann et al.   JOURNAL OF PHYSIOLOGY-LONDON

The Na–K–Cl Co-transporter in astrocyte swelling

(2010) Arumugam R. Jayakumar et al.   METABOLIC BRAIN DISEASE

Increased Na, K-ATPase α2 isoform gene expression by ammonia in astrocytes and in brain in vivo

(2010) Zhanxia Xue et al.   NEUROCHEMISTRY INTERNATIONAL

Astrocyte ERK phosphorylation precedes K+-induced swelling but follows hypotonicity-induced swelling

(2010) Liping Cai et al.   NEUROPATHOLOGY

Effect of canrenone on left ventricular mechanics in patients with mild systolic heart failure and metabolic syndrome: The AREA-in-CHF study

(2010) G. de Simone et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Spironolactone Attenuates Experimental Uremic Cardiomyopathy by Antagonizing Marinobufagenin

(2009) Jiang Tian et al.   HYPERTENSION

Effects of nicotine on K+ currents and nicotinic receptors in astrocytes of the hippocampal CA1 region

(2009) Miriam Hernández-Morales et al.   NEUROPHARMACOLOGY

Molecular Mechanisms of Ischemic Cerebral Edema: Role of Electroneutral Ion Transport

(2009) Kristopher T. Kahle et al.   PHYSIOLOGY

SPAK and OSR1: STE20 kinases involved in the regulation of ion homoeostasis and volume control in mammalian cells

(2008) Eric Delpire et al.   BIOCHEMICAL JOURNAL

Ammonium-evoked alterations in intracellular sodium and pH reduce glial glutamate transport activity

(2008) Tony Kelly et al.   GLIA

Na-K-Cl Cotransporter-1 in the Mechanism of Ammonia-induced Astrocyte Swelling

(2008) Arumugam R. Jayakumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE