Pharmacological Rescue of Hippocampal Fear Learning Deficits in Fragile X Syndrome
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Pharmacological Rescue of Hippocampal Fear Learning Deficits in Fragile X Syndrome
Authors
Keywords
Fragile X syndrome, Hippocampus, Rac1 inhibitor, Learning
Journal
MOLECULAR NEUROBIOLOGY
Volume 55, Issue 7, Pages 5951-5961
Publisher
Springer Nature
Online
2017-11-11
DOI
10.1007/s12035-017-0819-5
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Increased Training Intensity Induces Proper Membrane Localization of Actin Remodeling Proteins in the Hippocampus Preventing Cognitive Deficits: Implications for Fragile X Syndrome
- (2017) L. A. Martinez et al. MOLECULAR NEUROBIOLOGY
- Co-regulation of mRNA translation by TDP-43 and Fragile X Syndrome protein FMRP
- (2016) Pritha Majumder et al. ACTA NEUROPATHOLOGICA
- Hippocampal Activation of Rac1 Regulates the Forgetting of Object Recognition Memory
- (2016) Yunlong Liu et al. CURRENT BIOLOGY
- Inability to activate Rac1-dependent forgetting contributes to behavioral inflexibility in mutants of multiple autism-risk genes
- (2016) Tao Dong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of Rac1 Activity in the Hippocampus Impairs the Forgetting of Contextual Fear Memory
- (2015) Lizhu Jiang et al. MOLECULAR NEUROBIOLOGY
- Labelling and optical erasure of synaptic memory traces in the motor cortex
- (2015) Akiko Hayashi-Takagi et al. NATURE
- NNZ-2566, a Novel Analog of (1–3) IGF-1, as a Potential Therapeutic Agent for Fragile X Syndrome
- (2015) Robert M. J. Deacon et al. NEUROMOLECULAR MEDICINE
- 7, 8-Dihydroxyflavone induces synapse expression of AMPA GluA1 and ameliorates cognitive and spine abnormalities in a mouse model of fragile X syndrome
- (2015) Mi Tian et al. NEUROPHARMACOLOGY
- Deletion of Fmr1 Alters Function and Synaptic Inputs in the Auditory Brainstem
- (2015) Sarah E. Rotschafer et al. PLoS One
- Reversal of activity-mediated spine dynamics and learning impairment in a mouse model of Fragile X syndrome
- (2014) Bernadett Boda et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- The Rac1 Inhibitor NSC23766 Suppresses CREB Signaling by Targeting NMDA Receptor Function
- (2014) H. Hou et al. JOURNAL OF NEUROSCIENCE
- Early Social Enrichment Rescues Adult Behavioral and Brain Abnormalities in a Mouse Model of Fragile X Syndrome
- (2014) Diego Oddi et al. NEUROPSYCHOPHARMACOLOGY
- Distribution of fragile X mental retardation protein in the human auditory brainstem
- (2014) K. Beebe et al. NEUROSCIENCE
- Failed Stabilization for Long-Term Potentiation in the Auditory Cortex of Fmr1 Knockout Mice
- (2014) Sungchil Yang et al. PLoS One
- Differential role of Rac in the basolateral amygdala and cornu ammonis 1 in the reconsolidation of auditory and contextual Pavlovian fear memory in rats
- (2014) Ping Wu et al. PSYCHOPHARMACOLOGY
- Rho GTPase signaling at the synapse: Implications for intellectual disability
- (2013) Wei Ba et al. EXPERIMENTAL CELL RESEARCH
- Memory, navigation and theta rhythm in the hippocampal-entorhinal system
- (2013) György Buzsáki et al. NATURE NEUROSCIENCE
- Exploring the Multifactorial Nature of Autism Through Computational Systems Biology: Calcium and the Rho GTPase RAC1 Under the Spotlight
- (2013) Fares Zeidán-Chuliá et al. NEUROMOLECULAR MEDICINE
- CYFIP1 Coordinates mRNA Translation and Cytoskeleton Remodeling to Ensure Proper Dendritic Spine Formation
- (2013) Silvia De Rubeis et al. NEURON
- Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486
- (2013) B. M. Dolan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The challenges of clinical trials in fragile X syndrome
- (2013) Sébastien Jacquemont et al. PSYCHOPHARMACOLOGY
- Impairment of fragile X mental retardation protein-metabotropic glutamate receptor 5 signaling and its downstream cognates ras-related C3 botulinum toxin substrate 1, amyloid beta A4 precursor protein, striatal-enriched protein tyrosine phosphatase, and homer 1, in autism: a postmortem study in cerebellar vermis and superior frontal cortex
- (2013) S Fatemi et al. Molecular Autism
- Maladaptive Dendritic Spine Remodeling Contributes to Diabetic Neuropathic Pain
- (2012) A. M. Tan et al. JOURNAL OF NEUROSCIENCE
- Evidence for a Fragile X Mental Retardation Protein-Mediated Translational Switch in Metabotropic Glutamate Receptor-Triggered Arc Translation and Long-Term Depression
- (2012) F. Niere et al. JOURNAL OF NEUROSCIENCE
- Genetic reduction of muscarinic M4 receptor modulates analgesic response and acoustic startle response in a mouse model of fragile X syndrome (FXS)
- (2011) Surabi Veeraragavan et al. BEHAVIOURAL BRAIN RESEARCH
- Modulation of dendritic spines and synaptic function by Rac1: A possible link to Fragile X syndrome pathology
- (2011) Odelia Y.N. Bongmba et al. BRAIN RESEARCH
- The 'invisible hand': regulation of RHO GTPases by RHOGDIs
- (2011) Rafael Garcia-Mata et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Bidirectional Regulation of Dendritic Voltage-Gated Potassium Channels by the Fragile X Mental Retardation Protein
- (2011) Hye Young Lee et al. NEURON
- Pharmacological inactivation of the small GTPase Rac1 impairs long-term plasticity in the mouse hippocampus
- (2011) Luis A. Martinez et al. NEUROPHARMACOLOGY
- Therapeutic Strategies in Fragile X Syndrome: Dysregulated mGluR Signaling and Beyond
- (2011) Christina Gross et al. NEUROPSYCHOPHARMACOLOGY
- Forgetting Is Regulated through Rac Activity in Drosophila
- (2010) Yichun Shuai et al. CELL
- Regulation of Synaptic Rac1 Activity, Long-Term Potentiation Maintenance, and Learning and Memory by BCR and ABR Rac GTPase-Activating Proteins
- (2010) D. Oh et al. JOURNAL OF NEUROSCIENCE
- Physiological Activation of Synaptic Rac>PAK (p-21 Activated Kinase) Signaling Is Defective in a Mouse Model of Fragile X Syndrome
- (2010) L. Y. Chen et al. JOURNAL OF NEUROSCIENCE
- Evidence for social anxiety and impaired social cognition in a mouse model of fragile X syndrome.
- (2008) Caitlyn H. McNaughton et al. BEHAVIORAL NEUROSCIENCE
- Neuropathic Pain Memory Is Maintained by Rac1-Regulated Dendritic Spine Remodeling after Spinal Cord Injury
- (2008) A. M. Tan et al. JOURNAL OF NEUROSCIENCE
- α-Tocopherol Protects Against Oxidative Stress in the Fragile X Knockout Mouse: an Experimental Therapeutic Approach for the Fmr1 Deficiency
- (2008) Yolanda de Diego-Otero et al. NEUROPSYCHOPHARMACOLOGY
- Advances in the Treatment of Fragile X Syndrome
- (2008) R. J. Hagerman et al. PEDIATRICS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started