Reversal of activity-mediated spine dynamics and learning impairment in a mouse model of Fragile X syndrome

Lovastatin Corrects Excess Protein Synthesis and Prevents Epileptogenesis in a Mouse Model of Fragile X Syndrome

(2013) Emily K. Osterweil et al.   NEURON

Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486

(2013) B. M. Dolan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impairment of TrkB-PSD-95 Signaling in Angelman Syndrome

(2013) Cong Cao et al.   PLOS BIOLOGY

Lifting the Mood on Treating Fragile X

(2012) Emily K. Osterweil et al.   BIOLOGICAL PSYCHIATRY

LTP Induction Translocates Cortactin at Distant Synapses in Wild-Type But Not Fmr1 Knock-Out Mice

(2012) R. R. Seese et al.   JOURNAL OF NEUROSCIENCE

Alteration of Synaptic Network Dynamics by the Intellectual Disability Protein PAK3

(2012) A. Dubos et al.   JOURNAL OF NEUROSCIENCE

Structural plasticity upon learning: regulation and functions

(2012) Pico Caroni et al.   NATURE REVIEWS NEUROSCIENCE

Genetic Removal of p70 S6 Kinase 1 Corrects Molecular, Synaptic, and Behavioral Phenotypes in Fragile X Syndrome Mice

(2012) Aditi Bhattacharya et al.   NEURON

Chronic Pharmacological mGlu5 Inhibition Corrects Fragile X in Adult Mice

(2012) Aubin Michalon et al.   NEURON

Delayed administration of a PTEN inhibitor BPV improves functional recovery after experimental stroke

(2012) L. Mao et al.   NEUROSCIENCE

PI3K-PKB/Akt Pathway

(2012) B. A. Hemmings et al.   Cold Spring Harbor Perspectives in Biology

Phosphoinositide-3-Kinase Activation Controls Synaptogenesis and Spinogenesis in Hippocampal Neurons

(2011) G. Cuesto et al.   JOURNAL OF NEUROSCIENCE

Fragile X Mental Retardation Protein Regulates New Neuron Differentiation in the Adult Olfactory Bulb

(2011) S. Scotto-Lomassese et al.   JOURNAL OF NEUROSCIENCE

Toward Fulfilling the Promise of Molecular Medicine in Fragile X Syndrome

(2010) Dilja D. Krueger et al.   Annual Review of Medicine

PTEN is recruited to the postsynaptic terminal for NMDA receptor-dependent long-term depression

(2010) Sandra Jurado et al.   EMBO JOURNAL

Loss of the Fragile X Mental Retardation Protein Decouples Metabotropic Glutamate Receptor Dependent Priming of Long-Term Potentiation From Protein Synthesis

(2010) Benjamin D. Auerbach et al.   JOURNAL OF NEUROPHYSIOLOGY

Excess Phosphoinositide 3-Kinase Subunit Synthesis and Activity as a Novel Therapeutic Target in Fragile X Syndrome

(2010) C. Gross et al.   JOURNAL OF NEUROSCIENCE

Dysregulation of mTOR Signaling in Fragile X Syndrome

(2010) A. Sharma et al.   JOURNAL OF NEUROSCIENCE

Delayed Stabilization of Dendritic Spines in Fragile X Mice

(2010) A. Cruz-Martin et al.   JOURNAL OF NEUROSCIENCE

Physiological Activation of Synaptic Rac>PAK (p-21 Activated Kinase) Signaling Is Defective in a Mouse Model of Fragile X Syndrome

(2010) L. Y. Chen et al.   JOURNAL OF NEUROSCIENCE

Fragile X Mental Retardation Protein Is Required for Synapse Elimination by the Activity-Dependent Transcription Factor MEF2

(2010) Brad E. Pfeiffer et al.   NEURON

Dendritic spine instability and insensitivity to modulation by sensory experience in a mouse model of fragile X syndrome

(2010) Feng Pan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabotropic glutamate receptor-dependent long-term potentiation

(2009) R. Anwyl   NEUROPHARMACOLOGY

Ras Signaling Mechanisms Underlying Impaired GluR1-Dependent Plasticity Associated with Fragile X Syndrome

(2008) H. Hu et al.   JOURNAL OF NEUROSCIENCE

LTP Promotes a Selective Long-Term Stabilization and Clustering of Dendritic Spines

(2008) Mathias De Roo et al.   PLOS BIOLOGY