Presenilin-1 Delta E9 Mutant Induces STIM1-Driven Store-Operated Calcium Channel Hyperactivation in Hippocampal Neurons

Attenuated presenilin-1 endoproteolysis enhances store-operated calcium currents in neuronal cells

(2016) Maria Ryazantseva et al.   JOURNAL OF NEUROCHEMISTRY

SOCE in neurons: Signaling or just refilling?

(2015) Lukasz Majewski et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Ca2+channel inhibitor 2-APB reverses β-amyloid-induced LTP deficit in hippocampus by blocking BAX and caspase-3 hyperactivation

(2015) Wei-Yan Hu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Combined single channel and single molecule detection identifies subunit composition of STIM1-activated transient receptor potential canonical (TRPC) channels

(2015) Alexander Asanov et al.   CELL CALCIUM

Phenotypic rescue of a Drosophila model of mitochondrial ANT1 disease

(2014) S. Vartiainen et al.   Disease Models & Mechanisms

STIM1 and STIM2 Proteins Differently Regulate Endogenous Store-operated Channels in HEK293 Cells

(2014) Alexey Shalygin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Familial Alzheimer’s disease–associated presenilin-1 alters cerebellar activity and calcium homeostasis

(2014) Diego Sepulveda-Falla et al.   JOURNAL OF CLINICAL INVESTIGATION

Store-Operated CRAC Channels Regulate Gene Expression and Proliferation in Neural Progenitor Cells

(2014) A. Somasundaram et al.   JOURNAL OF NEUROSCIENCE

Native store-operated calcium channels are functionally expressed in mouse spinal cord dorsal horn neurons and regulate resting calcium homeostasis

(2014) Jingsheng Xia et al.   JOURNAL OF PHYSIOLOGY-LONDON

Reduced Synaptic STIM2 Expression and Impaired Store-Operated Calcium Entry Cause Destabilization of Mature Spines in Mutant Presenilin Mice

(2014) Suya Sun et al.   NEURON

Physiological Function and Characterization of TRPCs in Neurons

(2014) Yuyang Sun et al.   Cells

Analysis of calcium homeostasis in fresh lymphocytes from patients with sporadic Alzheimer's disease or mild cognitive impairment

(2013) Anna Jaworska et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Familial Alzheimer's disease-linked presenilin-1 mutation M146V affects store-operated calcium entry: Does gain look like loss?

(2013) M. Ryazantseva et al.   BIOCHIMIE

Involvement of presenilin holoprotein upregulation in calcium dyshomeostasis of Alzheimer's disease

(2013) Kamran Honarnejad et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Pharmacological and Genetic Reversal of Age-Dependent Cognitive Deficits Attributable to Decreased presenilin Function

(2013) S. M. J. McBride et al.   JOURNAL OF NEUROSCIENCE

Dysregulation of neural calcium signaling in Alzheimer disease, bipolar disorder and schizophrenia

(2013) Michael J. Berridge   Prion

The Presenilin-1 ΔE9 Mutation Results in Reduced γ-Secretase Activity, but Not Total Loss of PS1 Function, in Isogenic Human Stem Cells

(2013) Grace Woodruff et al.   Cell Reports

A critical role for STIM1 in filopodial calcium entry and axon guidance

(2013) Sangwoo Shim et al.   Molecular Brain

Cellular consequences of the expression of Alzheimer's disease-causing presenilin 1 mutations in human neuroblastoma (SH-SY5Y) cells

(2012) John P. Boyle et al.   BRAIN RESEARCH

Store-operated Ca2+ entry in hippocampal neurons: Regulation by protein tyrosine phosphatase PTP1B

(2012) David J. Koss et al.   CELL CALCIUM

STIM1 is necessary for store-operated calcium entry in turning growth cones

(2012) Camilla B. Mitchell et al.   JOURNAL OF NEUROCHEMISTRY

Muscarinic receptor activation determines the effects of store-operated Ca2+-entry on excitability and energy metabolism in pyramidal neurons

(2011) Oliver Kann et al.   CELL CALCIUM

Neuronal Store-Operated Calcium Entry Pathway as a Novel Therapeutic Target for Huntington's Disease Treatment

(2011) Jun Wu et al.   CHEMISTRY & BIOLOGY

Transient Receptor Potential Channel 1 (TRPC1) Reduces Calcium Permeability in Heteromeric Channel Complexes

(2011) Ursula Storch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of a Drosophila Alzheimer's Disease Model: Pharmacological Rescue of Cognitive Defects

(2011) Ranjita Chakraborty et al.   PLoS One

Differential Roles for STIM1 and STIM2 in Store-Operated Calcium Entry in Rat Neurons

(2011) Joanna Gruszczynska-Biegala et al.   PLoS One

Local Ca2+ Entry Via Orai1 Regulates Plasma Membrane Recruitment of TRPC1 and Controls Cytosolic Ca2+ Signals Required for Specific Cell Functions

(2011) Kwong Tai Cheng et al.   PLOS BIOLOGY

Review Article: Genetics of Alzheimer Disease

(2010) Lynn M. Bekris et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

Inositol 1,4,5-Trisphosphate Receptor and dSTIM Function in Drosophila Insulin-Producing Neurons Regulates Systemic Intracellular Calcium Homeostasis and Flight

(2010) N. Agrawal et al.   JOURNAL OF NEUROSCIENCE

Age-dependent cognitive impairment in a Drosophila Fragile X model and its pharmacological rescue

(2009) Catherine H. Choi et al.   BIOGERONTOLOGY

Intracellular Ca2+ signaling and store-operated Ca2+ entry are required in Drosophila neurons for flight

(2009) G. Venkiteswaran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STIM2 Regulates Capacitive Ca2+ Entry in Neurons and Plays a Key Role in Hypoxic Neuronal Cell Death

(2009) A. Berna-Erro et al.   Science Signaling

Alzheimer's disease: insights from Drosophila melanogaster models

(2009) Aileen Moloney et al.   TRENDS IN BIOCHEMICAL SCIENCES

Excess protein synthesis in Drosophila Fragile X mutants impairs long-term memory

(2008) François V Bolduc et al.   NATURE NEUROSCIENCE